Brightsurf Science News & Current Events

December 07, 2013
Genetic mutations and molecular alterations may explain racial differences in head and neck cancers
A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.

International gene therapy trial for 'bubble boy' disease shows promising early results
Researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome, a fatal genetic immunodeficiency also known as

Survey: Knowledge about HPV vaccine effectiveness lacking
Knowledge about the efficacy of the human papillomavirus (HPV) vaccine in preventing cervical cancer was lacking in the majority of survey respondents for whom the information would be relevant, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec.

Rare cause of anemia in newborns often overlooked, research suggests
Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

T cell immunotherapy: Promising results in children and adults with leukemia
Nearly 90 percent of children and adults with a highly aggressive form of acute lymphoblastic leukemia showed no evidence of cancer after receiving a novel, personalized cell therapy that reprograms a patient's immune system.

High-tech gene-therapy advances offer hope for patients with hard-to-treat blood disorders
A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology Annual Meeting and Exposition in New Orleans.

Advances in stem cell transplantation strategies show promise to improve availability, success
Hematopoietic stem cell transplantation, once considered an effective yet risky alternative to drug therapy for blood cancer, has become more accessible and successful in a wide range of patients as a result of major advances in transplant strategies and technologies.

Penn Medicine team reports on study of first 59 leukemia patients who received cell therapy
Three and a half years after beginning a clinical trial which demonstrated the first successful and sustained use of genetically engineered T cells to fight leukemia, a research team from the University of Pennsylvania will announce the latest data on 59 adults and children with advanced blood cancers that have failed to respond to standard therapies.

Age shouldn't limit access to transplants for MDS, study suggests
Patients with myelodysplastic syndromes who were as old as 74 fared as well with stem cell transplantation as did patients in the 60-to-65 age range, according to a study from Dana-Farber Cancer Institute presented at the annual meeting of the American Society of Hematology.

An important discovery of marine fossils in the upper part of the Permian Linxi Formation, China
Large numbers of marine fossils have been discovered for the first time in the limestone of the upper part of the Linxi Formation in the Guandi section, Linxi County, eastern Inner Mongolia.

Certain genetic alterations may explain head and neck cancer survival disparities
Certain genetic alterations to the PAX gene family may be responsible for survival disparities seen between African-American and non-Latino white men with head and neck cancer, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec.
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