Brightsurf Science News & Current Events

April 19, 2015
Investigational personalized cellular therapy tolerated well by patients
Genetically modified versions of patients' own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Perelman School of Medicine at the University of Pennsylvania.

New subsets of lung cancer with KRAS gene mutations identified
Mutations of the KRAS gene are commonly known to lead to cancer.

Schools must track academic progress of homeless students, researchers argue
Schools must track the academic progress of homeless students with as much care as they track special education, Title I and English language learner students, according to researchers at University of the Pacific.

Getting foster youth through college will take structured support, study concludes
The college graduation rate for students who have lived in foster care is 3 percent, among the lowest of any demographic group in the country.

For many US teachers, the classroom is a lonely place
Compared to their peers around the globe, US teachers continue to work largely in isolation, engaging less often in collaborative teaching and feedback that can transform teaching and learning, according to a Boston College professor and leading expert on teaching and school leadership.

Penn Medicine: Immunotherapy drug pembrolizumab shows promise for mesothelioma patients
The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

New combo of immunotherapy drugs is safe, shrinks tumors in metastatic melanoma patients
Once again, researchers at Penn's Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.

Yale-NUS, NUS and UT Austin researchers establish theoretical framework for graphene physics
A team of researchers from Yale-NUS College, the National University of Singapore and the University of Texas at Austin, USA, have established a theoretical framework to understand the elastic and electronic properties of graphene.

The Lancet Infectious Diseases: Leading doctors warn that sepsis deaths will not be curbed without radical rethink of research strategy
Leading doctors today warn that medical and public recognition of sepsis -- thought to contribute to between a third and a half of all hospital deaths -- must improve if the number of deaths from this common and potentially life-threatening condition are to fall.

Seeking new targets for ovarian cancer treatment
Identifying molecular changes that occur in tissue after chemotherapy could be crucial in advancing treatments for ovarian cancer, according to research from Magee-Womens Research Institute and Foundation and the University of Pittsburgh Cancer Institute presented today at the American Association for Cancer Research Annual Meeting 2015.

Broccoli sprout extract promising for head and neck cancer prevention
Broccoli sprout extract protects against oral cancer in mice and proved tolerable in a small group of healthy human volunteers, the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, announced today at the American Association for Cancer Research (AACR) Annual Meeting in Philadelphia.

Literacy app improves school readiness in at-risk preschoolers
Using mobile apps in preschool classrooms may help improve early literacy skills and boost school readiness for low-income children, according to research by NYU's Steinhardt School of Culture, Education, and Human Development.

Shared risk factors lead to diabetes, heart disease and cancer, says major AACR symposium
In a major symposium at the American Association for Cancer Research Annual Meeting 2015, University of Colorado Cancer Center investigator Tim Byers, M.D., M.P.H., describes research showing the link between cancer, diabetes and cardiovascular disease.

Gene signatures predict doxorubicin response in K9 osteosarcoma
University of Colorado Cancer Center members at CSU Flint Animal Cancer Center present at AACR 2015, a gene expression model that predicts canine osteosarcoma response to doxorubicin, potentially allowing veterinary oncologists to better choose which drug to use with their patients.

Animal study shows why long-time consumption of soyfoods reduces breast cancer recurrence
Women diagnosed with breast cancer are often told not to eat soyfoods or soy-based supplements because they can interfere with anti-estrogen treatment.

Driver of non-small cell lung cancer, FGFR1, also in 23 percent of small cell lung cancer
University of Colorado Cancer Center research presented at AACR 2015 shows that promising treatments in development for non-small cell lung cancer may be applicable to small cell lung cancer, as well.
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