Brightsurf Science News & Current Events

December 06, 2015
Study shows ibrutinib superior to traditional chemotherapy in untreated chronic leukemia patients
A multi-center, international, randomized, Phase III study of older untreated patients with chronic lymphocytic leukemia (CLL) demonstrated that ibrutinib, a kinase inhibitor, is significantly more effective than traditional chemotherapy with chlorambucil.

Researchers unravel mysteries of SCN8A mutation in epilepsy
Three studies presented at the American Epilepsy Society's (AES) 69th Annual Meeting explore the effects of mutations in the SCN8A gene, thought to underlie early infantile epileptic encephalopathy (EIEE) and other neurological conditions.

Radio shadow reveals tenuous cosmic gas cloud
Astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) have discovered the most tenuous molecular gas ever observed.

Study shows age doesn't affect survival outcomes in patients with MDS who receive a HCT
Prospective study, presented at the 57th Annual Meeting of the American Society of Hematology, shows age doesn't affect survival outcomes in patients with myelodysplastic syndrome (MDS) who receive a hematopoietic cell transplant.

New juvenile myoclinic epilepsy research from American Epilepsy Society's Annual Meeting
Researchers from Cardiff University, the University of Liverpool and Swansea University presented a new study revealing that people with drug-resistant juvenile myoclonic epilepsy have a 10 percent chance of having a common copy number variation.

Children with childhood leukemia benefit from prophylactic antibiotics
Prophylactic antibiotics significantly reduce the risk of serious bacterial infections in children during the critical first month of treatment for acute lymphoblastic leukemia (ALL), the most common childhood cancer, according to a US and Canadian study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

Matchmaker lets calcium flow
Among a wide variety of functions that impact nearly every aspect of cellular life, calcium signaling regulates the activity of T cells, which are an integral part of any effective immune response.

Early gene therapy results in Wiskott-Aldrich syndrome promising
Researchers reported promising preliminary outcomes for the first four children enrolled in a US gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the annual meeting of the American Society of Hematology.

To earn gratitude, put some effort into it
Researchers found that when done with high effort, the trivial courtesy of holding the door for others can inspire a 'thank you' or a favor in return, creating a virtuous cycle of gratitude.

IOF Young Investigator Awards recognize research excellence in the bone field
The International Osteoporosis Foundation (IOF) has presented the IOF Young Investigator Research Awards to the five young investigators in recognition of their outstanding research.

Personalized medicine studies reveal gene targets for epilepsy
Technological advances ranging from gene editing to next-generation sequencing offer unprecedented access to the human genome and promise to reshape the diagnosis and treatment of epilepsy.

Clinical trial results show new drug is better for CLL patients
Older adults with chronic lymphocytic leukemia may have an alternative to toxic chemotherapy as their first treatment, according to a national study to be reported online Dec.

Australian study finds 'no-drill' dentistry stops tooth decay
A University of Sydney study has revealed that tooth decay (dental caries) can be stopped, reversed, and prevented without the need for the traditional 'fill and drill' approach that has dominated dental care for decades.

Emerging technologies help advance the understanding, detection and control of epilepsy
A smartphone-induced EEG waveform and an intelligent algorithm for seizure detection are among the emerging technologies to be unveiled at the American Epilepsy Society's 69th Annual Meeting.

New vaccine strategy better protects high-risk cancer patients from flu
Yale Cancer Center researchers have developed a vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza.

Chronic lymphocytic leukemia mutations suggest new uses of existing cancer drugs
Mining the DNA of chronic lymphocytic leukemia (CLL) patients uncovered 12 mutations that may be targetable using therapies already available for other cancers, Penn Medicine researchers reported at the 57th annual meeting of the American Society of Hematology.

Frugal antibiotic prescribing associated with lower GP satisfaction scores
Reduced antibiotic prescribing is associated with lower patient satisfaction on the national General Practice Patient Survey, according to a new study by King's College London.
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