Brightsurf Science News & Current Events

June 04, 2016
Rucaparib shows clinical benefit in pancreatic cancer patients with BRCA mutation
The targeted therapy rucaparib, which has demonstrated robust clinical activity in ovarian cancer patients with a BRCA mutation, also showed promise in previously treated pancreatic cancer patients with the mutation.

Hispanic and black young adult cancer patients more likely to die of their disease
'What this means is that black and Hispanic young adult patients are almost 75 percent more likely to die after being diagnosed with liver cancer than are white young adult patients,' says University of Colorado Cancer Center researcher.

Study shows why immune-boosting therapy doesn't work for everyone with widespread melanoma
Patients who don't respond to treatments that use their own immune cells to destroy tumors, called tumor infiltrating lymphocytes, share changes in mechanisms that switch genes on or off in those cells, according to study results presented at the annual meeting of the American Society for Clinical Oncology (ASCO) on June 4, 2016 in Chicago.

Direct patient engagement through social media speeds recruitment to cancer research study
A crowd-sourcing strategy aimed at accelerating research into metastatic breast cancer has registered more than 2,000 patients from all 50 states in its first seven months, report researchers from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard at the American Society of Clinical Oncology Annual Meeting.

Moffitt: Radiation therapy with pembrolizumab, bevacizumab safe for glioma patients
Moffitt Cancer Center will present preliminary results from a phase 1 study testing whether the addition of pembrolizumab to radiation therapy and bevacizumab is safe and can control tumor growth for these patients.

Wnt stem cell signaling pathway implicated in colorectal cancer in patients under 50
A study of 4,699 tumor samples, presented at ASCO, finds Wnt pathway genes CTNNB1 and FAM123B specifically upregulated in colorectal cancer of patients under age 50.

New pre-surgery technique may make colostomy bags redundant for emergency bowel cancer patients
AN expandable tube that unblocks the bowel before surgery could lead to fewer cancer patients -- diagnosed as emergencies -- needing a colostomy bag.

Twice a day radiotherapy halves treatment time and is equally good at treating small cell lung cancer
HAVING radiotherapy once a day for six and a half weeks or twice a day for three weeks -- when combined with chemotherapy -- is equally good at treating small cell lung cancer that hasn't spread.

UTSW team find up to one-quarter of lung cancer patients ineligible for immunotherapy
A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C.

UH Seidman Cancer Center experts to present data at 52nd ASCO Annual Meeting
Researchers from University Hospitals Seidman Cancer Center and Case Western Reserve University School of Medicine will present data from several studies, including one that built an online tool used to estimate individualized survival for patients with newly-diagnosed glioblastoma (GBM), at American Society for Clinical Oncology Annual Meeting.

As colorectal cancer rate falls, diagnosis of late-stage cancer in young patients is up
University of Colorado Cancer Center study presented at the American Society for Clinical Oncology (ASCO) Annual Meeting 2016 finds that in patients over 50, the rate of CRC is falling at 2.5 percent per year while the rate of CRC in patients under 50 is rising at 0.8 percent per year.

MD Anderson study identifies significant cost differences between breast cancer chemotherapy regimens
Costs associated with different breast cancer chemotherapy regimens can vary significantly, regardless of effectiveness, according to new research from The University of Texas MD Anderson Cancer Center.
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