Brightsurf Science News & Current Events

December 09, 2017
International team identifies genetic model for predicting primary myelofibrosis outcomes
A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

Physical activity data, emojis on Apple Watch correlated with patient-reported outcomes
Wearable activity monitors, such as the Apple Watch, provide objective, continuous activity data that correlate with established patient-reported outcomes for cancer patients, according to a poster presentation by Mayo Clinic researchers that was presented at the American Society of Hematology Annual Meeting in Atlanta.

Immunotherapy drug nearly eliminates severe acute graft-versus-host disease
Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology (ASH) Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

Study explores use of checkpoint inhibitors after relapse from donor stem cell transplant
Immunotherapy agents known as checkpoint inhibitors have shown considerable promise in patients with hematologic cancers who relapse after a transplant with donor stem cells.

St. Jude gene therapy improves immunity in babies with 'bubble boy' disease
Preliminary findings indicate gene therapy pioneered at St. Jude Children's Research Hospital is safe and effective for babies with a devastating inherited disorder that leaves them with little or no immune protection.

For leukemia patients, transfusion needs may delay hospice care
Researchers report that thousands of leukemia patients who received frequent transfusions had very short stays in hospice at the end of life, suggesting that transfusion dependence presents a barrier to making meaningful use of palliative care.

A bird in the bush is worth $223,851 in the hand
The arrival of a single Black-backed Oriole bird in rural Pennsylvania - 5000 kilometres from its usual home in Mexico - was worth an estimated $US 223,851 to the economy from bird watchers flocking to see it.
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