Brightsurf Science News & Current Events

June 04, 2018
Proxies who watch advanced care planning video more likely to withhold feeding tubes
Researchers from Hebrew SeniorLife's Institute for Aging Research (IFAR) and Massachusetts General Hospital (MGH) have discovered that nursing home residents with advanced dementia are more likely to have advance directives that indicate they did should not get feeding tubes after their proxies viewed a 12-minute video on advance care planning.

Study: Exercise mitigates genetic effects of obesity later in life
A new study suggests, for the first time in women over age 70, that working up a sweat can reduce the influence one's genes have on obesity.

First study of neoadjuvant use of PARP inhibitor shows promise for early-stage, BRCA+ breast cancer patients
In a small Phase II study of early-stage breast cancer patients with BRCA1/2 mutations, researchers at The University of Texas MD Anderson Cancer Center found that more than half of the women who took the PARP inhibitor talazoparib once daily prior to surgery had no evidence of disease at the time of surgery.

Try togetherness: Study promotes cooperative weed management to curb herbicide resistance
In the fight against herbicide resistance, farmers are working with a shrinking toolkit.

Dementia patients could remain at home longer thanks to ground breaking technology
Innovative new technology will enable people with dementia to receive round the clock observation and live independently in their own homes, a new study in the Journal PL0S One reports.

More frequent screening after prostate cancer treatment not linked to improved survival
A study by a UNC Lineberger Comprehensive Cancer Center researcher and colleagues assessed whether monitoring prostate cancer patients following treatment with a PSA test every three months versus once a year would provide a long-term survival benefit.

'Miracle treatment' long-term success for babies with diabetes
Half of all cases of neonatal diabetes are caused by a mutation in the KCNJ11 gene, involved in keeping insulin-producing cells in the pancreas working properly.

New mechanisms discovered to separate air
Unlike the windows of your house, nanoscale holes in graphene (named as 'nanowindows') can selectively choose which type of air molecules can pass through.

Engineered cotton uses weed-suppression chemical as nutrient
A newly developed fertilizer system will provide nutrition to engineered cotton crops worldwide and a deadly dose to weeds that are increasingly herbicide resistant, according to a Texas A&M AgriLife Research study.

When it comes to school recess, a quality playground experience matters
Playground safety, access to play equipment, peer conflict resolution and quality engagement between adults and students are among the factors that contribute to a quality recess experience, new research from Oregon State University shows.

Novel PET imaging noninvasively pinpoints colitis inflammation
A novel positron emission tomography (PET) imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease.

Direct coupling of the Higgs boson to the top quark observed
An observation made by the CMS experiment at CERN unambiguously demonstrates the interaction of the Higgs boson and top quarks, which are the heaviest known subatomic particles.

Training the next generation of One Health professionals
There are now at least 45 'One Health' programs in the U.S. alone.

Global warming can be limited to 1.5°C by changing how we travel, heat homes, use devices
Global warming can be limited to 1.5°C by unprecedented improvements in the energy efficiency of everyday activities, according to new research from an international team of scientists at IIASA.

Increased follow-up does not benefit colorectal cancer patients
Logically, it would seem that more follow-up testing of cancer patients must be better than less - but this is not the case for patients who undergo surgery for colorectal cancer.

Regular exercise may be more beneficial for men than post-menopausal women
The blood vessels of middle-aged men and women adapt differently to regular exercise according to new research being presented today at the British Cardiovascular Society conference in Manchester.

Asthma and flu: a double whammy
Vaccinating asthmatic pre-schoolers against influenza would dramatically reduce their risk of being hospitalized after an attack, Canadian researchers find.

Inflammatory signals in heart muscle cells linked to atrial fibrillation
Interfering with inflammatory signals produced by heart muscle cells might someday provide novel therapeutic strategies for atrial fibrillation, according to an international team of researchers.

Trauma from parents' youth linked to poorer health, asthma in their own children
A Drexel University study found that for each type of adverse childhood experience a parent went through, their children had 19 percent higher odds of poorer health.

HIV vaccine elicits antibodies in animals that neutralize dozens of HIV strains
An experimental vaccine regimen based on the structure of a vulnerable site on HIV elicited antibodies in mice, guinea pigs and monkeys that neutralize dozens of HIV strains from around the world.

Acute coronary syndrome patients with short sleep have double odds of hospital readmission
Pilot data from a recent study suggest that patients with short sleep have over two times the odds of readmission than those with sufficient sleep duration during the month following acute coronary syndrome evaluation.

'Carbon bubble' coming that could wipe trillions from the global economy
Unlike current expectations, new research suggests that the prospects of the fossil-fuel industry are not bright, and that its demise may have profound economic and geopolitical consequences.

NASA spots tropical depression 05W approaching China's Hainan Island
In July of 2016, Tropical Cyclone 05W was approaching Hainan Island, China.

NIST atomic clock comparison confirms key assumptions of 'Einstein's elevator'
By comparing different types of remote atomic clocks, physicists at the National Institute of Standards and Technology (NIST) have performed the most accurate test ever of a key principle underlying Albert Einstein's famous theory of general relativity, which describes how gravity relates to space and time.

New algorithm determines ideal caffeine dosage and timing for alertness
According to a recent study, a newly developed algorithm may be the key to optimizing alertness with caffeine.

Childhood cancer survivors more likely to experience sleep problems as adults
Preliminary results from a study of childhood cancer survivors show that they are more likely to experience sleep problems and daytime sleepiness as adults, and those who report poor sleep have a greater likelihood of persistent or worsened emotional distress.

Designer materials with completely random structures might enable quantum computing
Topological randomness may be the answer for lossless electronics and making the nuts and bolts of quantum computers.

Brain structure may predict diet success
Differences in the structure of the prefrontal cortex predict an individual's ability to make healthier food choices, according to a new analysis of previous research in healthy men and women.

New algorithm fuses quality and quantity in satellite imagery
Using a new algorithm, University of Illinois researchers may have found the solution to an age-old dilemma plaguing satellite imagery -- whether to sacrifice high spatial resolution in the interest of generating images more frequently, or vice versa.

On the origins of agriculture, researchers uncover new clues
Researchers have uncovered evidence that underscores one long-debated theory: that agriculture arose out of moments of surplus, when environmental conditions were improving, and populations lived in greater densities.

Hats on for Easter Island statues
How do you put a 13-ton hat on a giant statue?

Limited health literacy is a major barrier to heart disease prevention and treatment
Limited health literacy is a major barrier to heart health and managing heart disease and stroke.

Improving patient transfer from ICU to ward: Resources, communication and culture
A new study has identified important factors that can improve the transfer of patients from the intensive care unit (ICU) to a general hospital ward, a high-risk transition in which breakdowns in communication, medical errors and adverse events resulting in readmission can occur.

Heart attack blood test sensitive enough to be used in portable device
A new blood test being developed to diagnose heart attacks could one day be carried out on a simple handheld device, giving a rapid diagnosis in A&E departments without the need for samples to be sent to a lab, according to new research presented today at the British Cardiovascular Society Conference in Manchester.

The health effect of air pollution from traffic
What would happen if all petrol and diesel-powered vehicles were removed from a smaller European city?

Doctors drive 3,000 miles to state conversation on male body image
Working toward your fitness goals can have some great health benefits, but how much is too much?

New cardiac pump device more effective, less costly than standard pump
Investigators from Brigham and Women's Hospital presented evidence that a next-generation cardiac pump device not only improves long-term outcomes but may also decrease cost of care over time for heart failure patients.

A major step towards individualized cancer therapy
Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in the US succeeded in establishing a versatile, powerful and convenient model to analyze human cancer.

New NSF special report released ahead of World Oceans Day: Catch a Wave! The Science of Summer

Personalized cancer vaccine may increase long-term survival in patients with deadly brain cancer
An international Phase III study led by researchers at UCLA has found that a personalized GBM vaccine may increase long-term survival in some patients.

Thank the moon for Earth's lengthening day
A new study that reconstructs the deep history of our planet's relationship to the moon shows that 1.4 billion years ago, a day on Earth lasted just over 18 hours.

Functional MRI reveals memory in sleeping toddlers
Our ability to remember past events develops rapidly in the first couple of years of life, but it's not clear exactly how this happens.

Mixed signals from poisonous moths
Poisonous moths use bright red spots to warn predators to avoid them -- but natural variation in these wing markings doesn't provide clear indications of how toxic individual moths might be -- new research shows.

Chinese researchers achieve 3D underwater acoustic carpet cloak first with 'Black Panther'-like features
A research team led by professor YANG Jun from the Institute of Acoustics (IOA) of the Chinese Academy of Sciences designed and fabricated a 3D underwater acoustic carpet cloak (UACC) using transformation acoustics.

Globular clusters 4 billion years younger than previously thought
Globular clusters could be up to 4 billion years younger than previously thought, new research led by the University of Warwick has found.

Idera Pharmaceuticals presents clinical data from the ILLUMINATE-204 trial of the combination of tilsotolimod and ipilimumab for anti-PD-1 refractory metastatic melanoma at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting
Idera Pharmaceuticals Inc., a clinical-stage biopharmaceutical company developing toll-like receptor and RNA therapeutics for patients with rare cancers and rare diseases, announced results from the ongoing ILLUMINATE-204 trial investigating tilsotolimod, Idera's intratumorally-delivered Toll-like Receptor 9 agonist, in combination with ipilimumab (Yervoy®).

Findings could lead to treatment of hepatitis B
Researchers have gained new insights into the virus that causes hepatitis B -- a life-threatening and incurable infection that afflicts more than 250 million people worldwide.

High-sensitivity troponin test reduces risk of future heart attack
The newer high-sensitivity troponin test discovers smaller amounts of heart-specific proteins, troponins, than the older troponin test and thus identifies more myocardial infarction patients than before.

Unlocking the genome
A team led by Prof. Stein Aerts (VIB-KU Leuven) uncovers how access to relevant DNA regions is orchestrated in epithelial cells.

English translation of IQWiG's updated General Methods now available
IQWiG published its updated methods in 2017, including new chapters on HTA topics proposed by the public and on the assessment of high-risk medical devices.

Study finds 2.6 percent mortality rate among children hospitalized for stroke
A major international study has found that 2.6 percent of infants and children hospitalized for stroke die in the hospital.

Light exposure during sleep may increase insulin resistance
According to preliminary results from a new study, nighttime light exposure during sleep may affect metabolic function.

Preschool home visiting program improves academic performance
A program of home visits designed to help families enhance school readiness for their preschool children had by the third grade improved academic performance, eased the social-emotional adjustment to school, and reduced problems at home for the children.

New study points to a potential 'Achilles heel' in brain cancer
Scientists at Virginia Commonwealth University believe they have uncovered an 'Achilles heel' of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer.

Hepatitis C guideline recommends screening for all people born 1945-1975
A key recommendation in a new Canadian guideline on managing chronic hepatitis C virus (HCV) is to screen all people born between 1945 and 1975 for the disease, a departure from previous guidelines.

Polarized cells give the heart its fully developed form
When it first starts to develop, the heart is a simple tube.

Alien apocalypse: Can any civilization make it through climate change?
Does the universe contain planets with truly sustainable civilizations? Or does every civilization that may have arisen in the cosmos last only a few centuries before it falls to the climate change it triggers?

Hard yet profitable
Researchers from the HSE Institute of Education surveyed teachers in vocational secondary schools in the Moscow Region, and compared the new advantages and disadvantages brought by the new conditions in their lives.

'Carbon bubble' coming that could wipe trillions from the global economy -- study
Macroeconomic simulations show rates of technological change in energy efficiency and renewable power are likely to cause a sudden drop in demand for fossil fuels, potentially sparking a global financial crisis.

Childhood cancer: The four survival strategies of tumor cells
Cancer cells in children tend to develop by following four main trajectories -- and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows.

A great majority of Mozambican adolescent girls are willing to be vaccinated against HPV
A study in Mozambique reveals that a majority of adolescent girls interviewed would be willing to get vaccinated against Human Papilloma Virus (HPV) if the vaccine was available in the country.

This monkey can plan out their foraging routes just like a human
Vervet monkeys can plan their foraging routes just like humans.

ASCO & NEJM: AI plus ovarian suppression yields benefit in high-risk younger breast cancer patients
Premenopausal women with hormone receptor-positive, HER2-negative breast cancer and a high risk of recurrence who are treated with an aromatase inhibitor plus ovarian function suppression may gain 10 to 15 percent improvement in freedom from distant recurrence at eight years, according to a new clinical trial analysis reported at the annual meeting of the American Society of Clinical Oncology.

Resolving molecule information in dynamic lipid membrane with metasurfaces
Researchers at EPFL (Switzerland) and their colleagues from the USA introduce a mid-infrared biosensor based on a novel multi-resonant metasurface, which, for the first time, is able to distinguish multiple analytes in heterogeneous biological samples non-destructively, in real-time and with high sensitivity.

Toxic toad invasion puts Madagascar's predators at risk, genetic evidence confirms
The recent introduction of the common Asian toad to Madagascar has led to fears that the toxic amphibian could wreak havoc on the island's already severely threatened fauna.

Spironolactone may be an alternative to antibiotics in women's acne treatment
In a finding that suggests the potential for practice change that would reduce the use of antibiotics in dermatology, researchers in the Perelman School of Medicine at the University of Pennsylvania have found the diuretic drug spironolactone may be just as effective as antibiotics for the treatment of women's acne.

New findings demonstrate how the food we eat affects biochemical signals in the gut
For years, researchers have studied how the body's microbiome impacts virtually every aspect of human health ranging from the immune system to mental wellness.

How does alcohol influence the development of Alzheimer's disease?
Research from the University of Illinois at Chicago has found that some of the genes affected by alcohol and inflammation are also implicated in processes that clear amyloid beta -- the protein that forms globs of plaques in the brain and which contributes to neuronal damage and the cognitive impairment associated with Alzheimer's disease.

The search for the origin of mast cells
A team of researchers from CNRS, INSERM and Aix-Marseille Université (AMU) at the Centre of immunology Marseille-Luminy, together with the Singapore Immunology Network, has proven that not all of the immune system's important mast cells are produced in bone marrow, as was previously thought.

Timing is everything to build kidneys from scratch
Perfectly punctual or fashionably late, it takes all kinds to build a kidney.

Long thought silent because of ice, study shows east Antarctica seismically active
Half of Antarctica has long thought to be seismically dormant, but a Drexel University researcher tripled the number of recorded earthquakes by monitoring for just one year.

Guppies change their eye color to deter rivals
Tiny fish called Trinidadian guppies turn their eyes black to warn other fish when they are feeling aggressive, new research shows.

Spooky quantum particle pairs fly like weird curveballs
Some particles that can be in two places at the same time and are not just particles but also waves, in this case, fermions, appear to move in even weirder ways than previously thought.

An abusive boss today might mean a better boss tomorrow
When bosses yell at you, your day can be ruined.

BU: Medicaid expansion increases volume and quality of care in rural areas
New study from Boston University School of Public Health finds that the first two years of Medicaid expansion were associated with increased coverage, better quality care, and more service use at rural community health centers.

Study links short and long sleep durations with excess heart age
Preliminary results from a new study show that excess heart age (EHA) appeared to be lowest among adults who reported sleeping seven hours per 24-hour period.

Easter Islanders used rope, ramps to put giant hats on famous statues
The ancient people of Easter Island, or Rapa Nui, were able to move massive stone hats and place them on top of statues with little effort and resources, using a parbuckling technique, according to new research from a collaboration that included investigators from Binghamton University, State University at New York.

Study suggests Earth could have supported continental crust, life earlier than thought
The early Earth might have been habitable much earlier than thought, according to new research from a group led by University of Chicago scientists.

Upgrading the toolbox for Duchenne muscular dystrophy research with a new rabbit model
Research to improve our understanding of Duchenne muscular dystrophy (DMD), and the development of new therapies, has previously relied on mouse models.

A change in bacteria's genetic code holds promise of longer-lasting drugs
By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

NFL teams play better during night games thanks to circadian advantages
Pilot data from a recent study suggest that NFL teams have better performance during night games versus afternoon games due to advantages from circadian rhythms.

Non-pharmacologic approaches improve outcomes for infants with neonatal abstinence syndrome
A quality improvement (QI) initiative at Boston Medical Center that focused on using non-pharmacologic approaches to care for infants with neonatal abstinence syndrome (NAS) yielded positive short-term outcomes for both the mothers and infants.

Preschool program preps kids for academic success through elementary school
A program that helps low-income parents prepare their children for school has benefits that extend beyond kindergarten and into into third grade, including performing better academically, acquiring better social emotional skills and needing fewer additional school services.

Storm's coming: New technique for simulation of extreme weather events
A Japanese researcher at Kanazawa University developed a new method for generating data for ensemble simulation of extreme weather phenomena.

Researchers lengthen intervals between blood draws for warfarin patients
A new study finds stable patients on blood thinners may not need to get their blood drawn as often as they currently do.

New nanoparticles help to detect serious scarring of wounds
A new way of seeing when heavy wound scars are forming, and providing doctors the chance to intervene, has been developed by scientists from Nanyang Technological University, Singapore (NTU Singapore) and Northwestern University in the United States.

When and where did the drought occur severely in the Yellow River basin during the last 55 years?
Drought is one of the severe natural disasters to impact human society and occurs widely and frequently in China.

New algorithm enhances ptychographic image reconstruction
Researchers from Berkeley Lab's Computational Research Division, the University of Texas at Dallas and Tianjin Normal University have developed an algorithmic model that enhances the image reconstruction capabilities of an algorithmic framework and computer software used to reconstruct millions of phases of ptychographic image data per second.

HIV study reveals new group of men at risk of infection
A study of HIV infection has identified a distinct group of men at risk of infection who have sex with other men, but are not open about their sexuality.

I saw that. Brain mechanisms create confidence about things seen
At the threshold of what we call consciousness is a brain function that makes you feel confidently aware that you are actually seeing what you see.

A non-negligible role of supports in atomically dispersed catalysts direct involvement in catalysis
Are the active sites of atomically dispersed catalysts limited to the dispersed metal atoms alone?

Novel gene in red blood cells may help adult newts regenerate limbs
Adult newts can repeatedly regenerate body parts. Researchers from Japan, including the University of Tsukuba, and the University of Daytona, have identified Newtic1, a gene that is expressed in clumps of red blood cells in the circulating blood.

Rutgers-led research could lead to more efficient electronics
A Rutgers-led team of physicists has demonstrated a way to conduct electricity between transistors without energy loss, opening the door to low-power electronics and, potentially, quantum computing that would be far faster than today's computers.

MIT researchers devise new way to make light interact with matter
Researchers at MIT and Technion have devised a new way to make light interact with matter.

T cells alone are sufficient to establish and maintain HIV infection in the brain
A new study by University of North Carolina School of Medicine researchers has found that T cells, a type of white blood cell and an essential part of the immune system, are sufficient by themselves to establish and maintain an HIV infection in the brain.

Chemical traces from star formation cast light on cosmic history
Fresh insight into intense star formation in distant galaxies is changing researchers' ideas about cosmic history.

Researchers study aquatic beetles native only to central Wyoming
The known range of the narrow-footed Hygrotus diving beetle, which also can fly, is in central Wyoming, in the Powder River Basin and one site in the Wind River Basin.

New approach to immunotherapy leads to complete response in breast cancer patient
A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in a patient who was unresponsive to all other treatments.

Collective gravity, not Planet Nine, may explain the orbits of 'detached objects'
Bumper car-like interactions at the edges of our solar system -- and not a mysterious ninth planet -- may explain the dynamics of strange bodies called 'detached objects,' according to a new study.

Preschool and school-age irritability predict reward-related brain function
Preschool irritability and concurrent irritability were uniquely associated with aberrant patterns of reward-related brain connectivity, highlighting the importance of developmental timing of irritability for brain function, finds a study published in the June 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP).

In MS, disintegrating brain lesions may indicate the disease is getting worse
For decades, clinicians treating multiple sclerosis (MS) have interpreted the appearance of new or expanding brain lesions on magnetic resonance imaging (MRI) scans as a sign that a patient's disease is getting worse.

ALMA and VLT find too many massive stars in starburst galaxies, near and far
Astronomers using ALMA and the VLT have discovered that both starburst galaxies in the early Universe and a star-forming region in a nearby galaxy contain a much higher proportion of massive stars than is found in more peaceful galaxies.

Does increased supervision of resident physicians reduce medical errors?
Increased supervision of residents by attending physicians who joined patient rounds didn't significantly reduce medical errors but residents reported decreased autonomy.

ChemMaps lets researchers navigate the chemical universe
A new online service -- ChemMaps -- allows users to interactively navigate the chemical space of over 8,000 drugs and 47,000 environmental compounds in 3D and real time.

NOvA experiment sees strong evidence for antineutrino oscillation
The NOvA collaboration has announced its first results using antineutrinos, and has seen strong evidence of muon antineutrinos oscillating into electron antineutrinos over long distances, a phenomenon that has never been unambiguously observed.

Gene linked to intellectual ability affects memory replay in mice
Researchers at the RIKEN Center for Brain Science in Japan have discovered that a gene associated with human intellectual ability is necessary for normal memory formation in mice.

Stanford study casts doubt on the predictive value of earthquake foreshocks
A Stanford-led study questions previous findings about the value of foreshocks as warning signs that a big earthquake is coming, instead showing them to be indistinguishable from ordinary earthquakes.

Self-sustaining loop of chemical reactions could revolutionize drug production
Experts from the University of Nottingham have created a self-sustaining circuit of reactions which is a greener and more efficient method of chemical production.

Medicaid expansion produces significant health benefits, study finds
The first peer-reviewed comprehensive analysis of the effects of Medicaid expansion paints a picture of significant improvements in various health outcomes consistent with the original goals of the Affordable Care Act, also known as Obamacare.

Male guppies grow larger brains in response to predator exposure -- but not females
Male guppies exposed to predators in the wild or in captivity have heavier brains than those living in relatively predator-free conditions, according to new research published in the journal Functional Ecology.

Study links screen time to insomnia symptoms and depressive symptoms in adolescents
Preliminary results from a new study indicate that greater amounts of daily screen time are associated with more insomnia symptoms and shorter sleep duration among adolescents.

Did extreme fluctuations in oxygen, not a gradual rise, spark the Cambrian explosion?
Five hundred and forty million years ago, during the Cambrian period, life suddenly went nuts.

Wireless system can power devices inside the body
MIT researchers have developed a new way to power and communicate with devices implanted deep within the human body.

Inadequate sleep could cost countries billions
Inadequate sleep is a public health problem affecting more than one in three adults worldwide.

Researchers find new way to estimate magma beneath Yellowstone supervolcano
Researchers at Washington State University and the University of Idaho have found a new way to estimate how fast magma is recharging beneath the Yellowstone supervolcano.

Blood formation: Researchers engineer human bone marrow tissue
Researchers have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time.

Cancer fighting effects of aspirin revealed in bowel tumor study
Researchers at the University of Edinburgh have shed light on how taking aspirin can help to stave off bowel cancer.

Does negative political advertising actually work?
While many may dread campaign season because of pervasiveness of negative political advertising, a new study in the INFORMS journal Marketing Science has found that negative political advertising actually works, but perhaps not in the way that many may assume.

New study finds plant protein, fiber, nuts lower cholesterol, improve blood pressure
A new meta-analysis finds that a diet that includes plant protein, fiber, nuts, and plant sterols lowers cholesterol and improves other markers for heart health.

New invention safely transports unknown, deep-dwelling fishes to the ocean's surface
Strange and beautiful fishes from the ocean's deep and lesser-known twilight zone reefs are hitching a ride to the surface thanks to the newly invented SubCAS (or Submersible Chamber for Ascending Specimens).

Experimental drug restores some bladder function after spinal cord injury, study finds
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function, new research suggests.

NCI-MATCH precision medicine clinical trial releases new findings
The released data is from three treatment arms, all single-arm phase 2 studies: the drug taselisib in patients with mutations in the PIK3CA gene (Arm I); the drug ado-trastuzumab emtansine (T-DM1) in patients with HER2-overexpressing tumors (Arm Q); and the drug AZD4547 in patients with mutations in the FGFR pathway (Arm W).

Beyond conventional solution-process for 2-D heterostructure
Recently, researchers from Nanjing Tech University, China, demonstrated a facile wet-chemical method to directly grow organic-inorganic hybrid perovskite (MAPbBr3, MA = CH3NH3+) NCs on surfaces of dispersible MoS2 nanosheets.

Capturing light in a waveguide array
Cheaper and more efficient photonic devices, such as lasers, optical fibers, and other light sources may be possible with confined light that is unaffected by imperfections in the material that confines it.

Future robots need no motors
The mechanical engineering team at the University of Hong Kong led by Professor Alfonso Ngan Hing-wan, Chair Professor in Materials Science and Engineering, have created a novel actuating material that can be powered by visible light, electricity, and other stimuli, and which may replace traditional bulky motors and pneumatic actuators with ones similar to mammalian skeletal muscles in the future.

How binging creates alcohol tolerance in flies
Repeated exposure to large quantities of alcohol may lead to tolerance by reducing the activity of a protein that regulates communication between neurons, according to a study of fruit flies published in eNeuro.

The role of cohesin in genome 3D structure helps for a better understanding of tumor cells
The genome spatial organization depends on a number of factors, the cohesin protein complex being one of them.

Checkpoint inhibitor shrinks advanced squamous cell skin cancer
Clinical trials show that an immune checkpoint inhibitor shrinks the tumors of nearly half of patients with an incurable, advanced form of a common skin cancer, an international team led by a researcher at The University of Texas MD Anderson Cancer Center reports in the New England Journal of Medicine.

Speed-accuracy tradeoff turns up gain in the brain
Widespread changes in neural activity enable people to quickly make a decision by 'turning up the gain in the brain,' suggests a human study published in eNeuro.

Two-step process underpins upkeep of key protein in cell division
Two complementary processes enable a critical protein, known as CENP-A, to be replenished to enable cells to divide, detailed analysis shows.

Digital, mobile advances will define future of cardiology
The future of cardiovascular care will be transformed by advances in artificial intelligence, digital health technology, and mobile as a means to prevent and treat heart disease, according to several review articles published today in a Journal of the American College of Cardiology Focus Seminar on the Future Technology of Cardiovascular Care.

Gap in substance abuse data could have long-term implications, study finds
A policy of redacting Medicare claims that included diagnosis or procedure codes related to substance abuse was in effect from 2013-2017, just as the Affordable Care Act and the opioid epidemic were drastically changing the healthcare landscape.

Physicists use terahertz flashes to uncover state of matter hidden by superconductivity
A research team led by Jigang Wang of Iowa State University and the Ames Laboratory has developed a new quantum switching scheme that gives them access to new and hidden states of matter.

Sleep paralysis and hallucinations are prevalent in student athletes
Pilot data from a recent study suggest that sleep paralysis and dream-like hallucinations as you are falling asleep or waking up are widespread in student athletes and are independently associated with symptoms of depression.

Bright warning colors on poison dart frogs also act as camouflage
Poison dart frogs are well known for their deadly toxins and bright colors, which have made them a classic example of warning coloration.

Density gradient ultracentrifugation for colloidal nanostructures separation and investigation
Density gradient ultracentrifugation (DGUC), as an efficient way of sorting colloidal nanoparticles, can realize the separation according to their differences in chemistry, structure, size and/or morphology.

Poor sleep at night could mean decreased work productivity in the morning
Preliminary results from a new study suggest that several sleep-related symptoms are associated with decreased work productivity.

Massive AI Twitter probe draws heat map of entrepreneurial personality
A QUT-led study using artificial intelligence has proved a Twitter-based personality estimate is as successful in predicting local differences in actual entrepreneurial activity as regional personality data collected by means of millions of standard personality tests.

Scientists find pre-earthquake activity in central Alaska
New research from University of Alaska Fairbanks Geophysical Institute professor Carl Tape may help future work in early warning systems for earthquakes.

Biomaterial particles educate immune system to accept transplanted islets
By instructing key immune system cells to accept transplanted insulin-producing islets, researchers have opened a potentially new pathway for treating type 1 diabetes. is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to