Brightsurf Science News & Current Events

October 17, 2020
Results from the cobra-reduce trial reported at TCT Connect
For patients undergoing percutaneous coronary intervention (PCI) that also require oral anticoagulation, treatment with a nanotechnology polymer-coated stent plus 14-day dual anti-platelet therapy (DAPT) did not reduce bleeding or establish non-inferior outcomes for thrombotic events compared with a drug-eluting stent (DES) and standard three or six-month DAPT therapy.

Echo from the past makes rice paddies a good home for wetland plants
Tokyo, Japan - Researchers from Tokyo Metropolitan University studied the biodiversity of wetland plants over time in rice paddies in the Tone River basin, Japan.

Molecular design strategy reveals near infrared-absorbing hydrocarbon
The lessons learned from a near infrared absorbing, bowl-shaped molecule made only from hydrogen and carbon atoms offers insights for future organic conductors.

Wearable pressure-sensitive devices for medical use
Novel design and strategic use of materials in a pressure-sensitive adhesive strip.

Oncotarget: Induction of phenotypic changes in HER2-postive breast cancer cells
The cover for issue 30 of Oncotarget features Figure 4, ''RNAseq results demonstrating differences between normal, cancer, and redirected cells,'' by Frank-Kamenetskii, et al. which reported that the influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not.

Results from the optimize trial reported at TCT Connect
The OPTIMIZE randomized trial comparing a novel, low-profile drug-eluting stent (DES) facilitating transradial access (TR) and direct stenting (DS) to existing DES did not establish non-inferiority of the new stent based on the prespecified study statistical analysis plan, likely due to the definition of periprocedural target vessel myocardial infarction (TVMI) coupled with a large proportion of high-sensitive cardiac troponin assays used in the trial.

Old methods prove true for studying proteins
A decades-old technique for probing protein motions proves more accurate than current practices.

Results from host-reduce-polytech-ACS trial reported at TCT Connect
A randomized clinical trial found that drug-eluting stents (DES) with durable polymers are non-inferior to DES with biodegradable polymers in patients with acute coronary syndrome (ACS).
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