Product Description One million cells in our bodies die every second--they commit suicide by a mechanism known as apoptosis. Apoptosis is essential for survival of the body as a whole and has critical roles in various developmental processes and the immune system.In Cell Death, Douglas Green provides a clear and comprehensive view of apoptosis and other cell death mechanisms. Taking a bottom-up approach, he starts with the enzymes that perform the execution process (a family of proteases termed caspases) and examines their cellular targets and the ways in which they are activated. He then looks at the molecular machinery that links signals that cause cell death to caspases, emphasizing the importance of the BCL-2 family of proteins and the role of cytochrome c released from mitochondria. The final stage of the process, phagocytic removal of dead or dying cells, is also covered.Green outlines the roles of apoptosis and death mechanisms such as necrosis in embryogenesis, neuronal selection, and the development of self-tolerance in the immune system. In addition, he explains how cell death defends the body against cancer and traces the evolutionary origins of the apoptosis machinery back over a billion years. This new edition contains critical new information on recent exciting advances in the field, such as new forms for cell death and important insights into the mechanisms and control of apoptosis. The book is thus of great use to all biologists interested in how cells function in the context of multicellular organisms and will appeal to everyone from undergraduates encountering the topic for the first time to researchers actively working in the field.
Best Science Podcasts 2018
We have hand picked the best science podcasts for 2018. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
The Right To Speak Should all speech, even the most offensive, be allowed on college campuses? And is hearing from those we deeply disagree with ... worth it? This hour, TED speakers explore the debate over free speech. Guests include recent college graduate Zachary Wood, political scientist Jeffrey Howard, novelist Elif Shafak, and journalist and author James Kirchick.
#486 Volcanoes This week we're talking volcanoes. Because there are few things that fascinate us more than the amazing, unstoppable power of an erupting volcano. First, Jessica Johnson takes us through the latest activity from the Kilauea volcano in Hawaii to help us understand what's happening with this headline-grabbing volcano. And Janine Krippner joins us to highlight some of the lesser-known volcanoes that can be found in the USA, the different kinds of eruptions we might one day see at them, and how damaging they have the potential to be. Related links: Kilauea status report at USGS A beginner's guide to Hawaii's otherworldly...