Cedars-Sinai medical tip sheet for January 2002

January 04, 2002

RESEARCHERS AT CEDARS-SINAI'S MAXINE DUNITZ NEUROSURGICAL INSTITUTE REPORT PROMISING RESULTS IN STUDY USING GENE MODIFICATION TO DELIVER INTERLEUKIN 12 DIRECTLY INTO RESISTANT TYPE OF BRAIN TUMOR

In an article appearing in the Dec. 28, 2001, issue of Cancer Gene Therapy, physicians and scientists at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe an approach that "significantly prolonged" survival in mice with glioma - an extremely deadly type of brain cancer that is highly resistant to treatment. In the study, IL-12 was attached to an adenovirus and administered directly into tumors of the right corpus striatum of the brain. Mice receiving the genetically modified virus survived longer than those that received an adenovirus alone and those that were given normal saline solution. According to the paper's senior author, John S. Yu, M.D., IL-12 also improved the immune system's ability to infiltrate and kill tumor cells.

USING APPROPRIATE ALTERNATIVE THERAPIES TO TREAT THE COMMON COLD MAY HELP AVOID THE SPREAD OF ANTIBIOTIC RESISTANCE

With antibiotic resistance fast becoming one of the world's most pressing public health problems, Dr. Mary Hardy, Medical Director of Cedars-Sinai's Integrative Medicine program, recommends certain alternative therapies as a reasonable way to combat the inappropriate use of antibiotics to treat the common cold. "Herbs, vitamins and other tried-and-true home remedies can be quite effective in treating routine, minor cold symptoms," says Dr. Hardy. "Chicken soup, ecinacea, zinc lozenges, and vitamin C are only some of the available alternatives that boost the immune system and can limit the severity of a cold, sore throat, or flu."

KICK-START THE NEW YEAR WITH SIX TIPS FOR KICKING BAD HABITS

Biting your nails because you've just quit smoking? Drinking more coffee because you can't stop biting your nails? Biting off people's heads in the morning because you've quit drinking coffee? When kicking bad habits, sometimes we "bite off more than we can chew." The Thalians Department of Psychiatry at Cedars-Sinai Medical Center in Los Angeles offers tips on kicking those bad habits safely for a healthy, happier New Year.

BLAZING NEW TRAILS IN ORGAN TRANSPLANTS: CHAVEZ SISTERS HOPE TO INCREASE UNDERSTANDING AND AWARENESS OF LIVING DONOR ORGAN TRANSPLANT IN HISPANIC COMMUNITIES

The Chavez family has something extra to celebrate this New Year - the gift of life, given from one sister to another. After 10 years of living with liver disease, Juanita Chavez, 30, received on Nov. 13, a portion of her sister Maria Elena's liver. The sisters are the daughters of Dolores Huerta, co-founder of the United Farmer Workers of America, AFL-CIO (UFW), and Richard Chavez, a long-term UFW board member and the brother of Cesar Chavez, also a UFW co-founder. Following their successful transplant, the sisters and their family are on a mission to enhance understanding and awareness of living donor organ transplants - especially in Hispanic communities.

CEDARS-SINAI DOCTORS OFFER ADVICE ON STAYING HEALTHY DURING THE FLU SEASON AND OUT OF THE E.R.

As winter approaches, health care providers are gearing up for the onset of influenza or "flu" season. "Not only are more people are admitted to the hospital during these flu periods, they are hospitalized for longer periods of time," says Joel Geiderman, M.D., co-chair of the department of emergency medicine. For those patients visiting the E.R., this means that more beds are filled and there may be a longer waiting period for health services. This news release contains tips for coping with the flu.

"LIKE MAGIC!" IS HOW RODNEY BLAUER DESCRIBES THE RESULTS OF HIS TWO ENDOSCOPIC BRAIN SURGERIES IN LESS THAN A YEAR

After undergoing two highly specialized types of minimally invasive skull base brain surgery in less than a year - one for an acoustic neuroma that was accidentally discovered and one for relief of the debilitating facial pain known as trigeminal neuralgia - 69-year-old Rodney Blauer says he is feeling great this New Year. His brain tumor is gone, as is his facial pain. Strange as it may sound, Blauer is actually thankful for his trigeminal neuralgia, as diagnosis of it led to the accidental discovery of an unrelated, and potentially life-threatening, tumor on the opposite side of his brain. Both operations were performed by Hrayr K. Shahinian, M.D., director of the Skull Base Institute at Cedars-Sinai Medical Center.

NEW DIRECTOR OF PEDIATRIC ORTHOPEDIC SURGERY WILL ESTABLISH ADDITIONAL CLINICS AND EXPAND RANGE OF SERVICES AT CEDARS-SINAI MEDICAL CENTER

Robert Matthew Bernstein, MD, has been named director of Pediatric Orthopedic Surgery at Cedars-Sinai Medical Center's Ahmanson Pediatric Center. He will direct a variety of specialty clinics for children with scoliosis, spina bifida, limb deformities and other conditions, and will be leading a new initiative in pediatric orthopedic surgery to expand the Medical Center's pediatric orthopedic surgery program.
-end-


Cedars-Sinai Medical Center

Related Brain Articles from Brightsurf:

Glioblastoma nanomedicine crosses into brain in mice, eradicates recurring brain cancer
A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier in mice could deliver cancer-killing drugs directly to malignant brain tumors, new research from the University of Michigan shows.

Children with asymptomatic brain bleeds as newborns show normal brain development at age 2
A study by UNC researchers finds that neurodevelopmental scores and gray matter volumes at age two years did not differ between children who had MRI-confirmed asymptomatic subdural hemorrhages when they were neonates, compared to children with no history of subdural hemorrhage.

New model of human brain 'conversations' could inform research on brain disease, cognition
A team of Indiana University neuroscientists has built a new model of human brain networks that sheds light on how the brain functions.

Human brain size gene triggers bigger brain in monkeys
Dresden and Japanese researchers show that a human-specific gene causes a larger neocortex in the common marmoset, a non-human primate.

Unique insight into development of the human brain: Model of the early embryonic brain
Stem cell researchers from the University of Copenhagen have designed a model of an early embryonic brain.

An optical brain-to-brain interface supports information exchange for locomotion control
Chinese researchers established an optical BtBI that supports rapid information transmission for precise locomotion control, thus providing a proof-of-principle demonstration of fast BtBI for real-time behavioral control.

Transplanting human nerve cells into a mouse brain reveals how they wire into brain circuits
A team of researchers led by Pierre Vanderhaeghen and Vincent Bonin (VIB-KU Leuven, Université libre de Bruxelles and NERF) showed how human nerve cells can develop at their own pace, and form highly precise connections with the surrounding mouse brain cells.

Brain scans reveal how the human brain compensates when one hemisphere is removed
Researchers studying six adults who had one of their brain hemispheres removed during childhood to reduce epileptic seizures found that the remaining half of the brain formed unusually strong connections between different functional brain networks, which potentially help the body to function as if the brain were intact.

Alcohol byproduct contributes to brain chemistry changes in specific brain regions
Study of mouse models provides clear implications for new targets to treat alcohol use disorder and fetal alcohol syndrome.

Scientists predict the areas of the brain to stimulate transitions between different brain states
Using a computer model of the brain, Gustavo Deco, director of the Center for Brain and Cognition, and Josephine Cruzat, a member of his team, together with a group of international collaborators, have developed an innovative method published in Proceedings of the National Academy of Sciences on Sept.

Read More: Brain News and Brain Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.