Nav: Home

Specific Technologies announces new results and a major new NIAID grant award

January 04, 2017

January 4, 2016 - MOUNTAIN VIEW, California Specific Technologies, which has developed a new diagnostic paradigm combining detection with ID of microorganisms growing in culture, today announces development of a new paradigm for the quantitative determination of antibiotic efficacy, within hours of positive blood culture, with minimal sample preparation and at a low cost. Together with the SpecID blood culture system, this antibiotic susceptibility testing (AST) system, SpeciFAST, offers phenotypic MIC matching CLSI gold standard results, in most cases within 3 hours from positive blood culture, while greatly simplifying workflow, and all at the cost of current practices which take days longer.

The new technology, initially developed for use directly with positive blood culture samples (it does not require removal of red blood cells), is equally suited for use with standard emulsions obtained from colonies, making it a candidate replacement platform for legacy systems in modern microbiology laboratories.

In conjunction with the announcement of this innovation, Specific Technologies has received notice of a new $2.9M National Institutes of Health award for development of this antibiotic susceptibility testing (AST) system. This is the fourth grant the Company has received from the NIH for the development of a disruptive system to increase the speed of time-to-answer for blood infection, a life-threatening condition where time is of the essence, even while reducing lab cost.

"The alarming increase in antibiotic resistant infections combined with a dearth of new antibiotics has increased the demand for rapid, reliable and affordable antibiotic susceptibility determination," said Gary Procop, Director of Molecular Microbiology, Virology, Mycology and Parasitology at the Cleveland Clinic Foundation. "We look forward to working with Specific to evaluate this promising new technology, and are delighted that NIAID has seen fit to so strongly support this work."

In awarding this funding, the NIAID study section concluded, "The panel agreed that the proposed antimicrobial susceptibility testing platform with better sensitivity and speed of detection compared to existing methods is of high biomedical significance and clinical impact because of its potential to improve detection, treatment, monitoring, and surveillance of microbial antibiotic resistance that can impact the overall antibiotic stewardship and reduce the global trends of emerging antibiotic microbial resistance, mortality, and healthcare costs. A significant clinical need, promising technology, convincing scientific premise based on impressive preliminary data, and high probability of success are strengths of this application. Moreover, thoughtful commercialization strategy, rigorous scientific and engineering design, and well-planned clinical collaborations are strengths."

"These new developments and recent grant award further demonstrate the broad and disruptive capabilities of our underlying technology for microbiology diagnostics," said Paul A. Rhodes, Ph.D., CEO of Specific Technologies. "We are developing a truly new diagnostic paradigm, based on the ability to monitor the unique pattern of volatiles emitted by all growing microorganisms. The impact is faster detection and ID of samples, and with SpeciFAST the fastest system yet-announced for phenotypic MIC determination."

"Our paradigm will be cost-effective, simple and easy to integrate into existing lab practice," said Rob Lozuk, President of Specific Technologies. "We have initiated collaborations with global thought leaders to accelerate development of this disruptive capability and look forward to broadly commercializing both SpecID and SpeciFAST."
-end-
About the SpecID System

During growth in culture, bacteria produce small molecule volatile metabolites unique to their species and strain. Utilizing a chemical fingerprint that combines detection and identification into a simple, automated single step using a low-cost disposable printed sensory array, the novel SpecID system identifies microorganism species and strain from the metabolomic signature of volatiles produced during growth.

About Specific Technologies

Specific Technologies has developed in vitro diagnostic systems based upon a unique, patented metabolomic signature technology that enables rapid identification of microorganisms. Its first commercial application applies this fundamental new platform to the detection and characterization of microorganisms causing blood stream infection, and to the rapid and low cost phenotypic determination of their antibiotic susceptibility. Specific Technologies is based in Mountain View, CA.

For press inquiries, please contact: press@specifictechnologies.net

Specific Technologies

Related Technology Articles:

October issue SLAS Technology now available
The October issue of SLAS Technology features the cover article, 'Role of Digital Microfl-uidics in Enabling Access to Laboratory Automation and Making Biology Programmable' by Varun B.
Robot technology for everyone or only for the average person?
Robot technology is being used more and more in health rehabilitation and in working life.
Novel biomarker technology for cancer diagnostics
A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden.
Technology innovation for neurology
TU Graz researcher Francesco Greco has developed ultra-light tattoo electrodes that are hardly noticeable on the skin and make long-term measurements of brain activity cheaper and easier.
April's SLAS Technology is now available
April's Edition of SLAS Technology Features Cover Article, 'CURATE.AI: Optimizing Personalized Medicine with Artificial Intelligence'.
Technology in higher education: learning with it instead of from it
Technology has shifted the way that professors teach students in higher education.
Post-lithium technology
Next-generation batteries will probably see the replacement of lithium ions by more abundant and environmentally benign alkali metal or multivalent ions.
Rethinking the role of technology in the classroom
Introducing tablets and laptops to the classroom has certain educational virtues, according to Annahita Ball, an assistant professor in the University at Buffalo School of Social Work, but her research suggests that tech has its limitations as well.
The science and technology of FAST
The Five hundred-meter Aperture Spherical radio Telescope (FAST), located in a radio quiet zone, with the targets (e.g., radio pulsars and neutron stars, galactic and extragalactic 21-cm HI emission).
AI technology could help protect water supplies
Progress on new artificial intelligence (AI) technology could make monitoring at water treatment plants cheaper and easier and help safeguard public health.
More Technology News and Technology Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: The Power Of Spaces
How do spaces shape the human experience? In what ways do our rooms, homes, and buildings give us meaning and purpose? This hour, TED speakers explore the power of the spaces we make and inhabit. Guests include architect Michael Murphy, musician David Byrne, artist Es Devlin, and architect Siamak Hariri.
Now Playing: Science for the People

#576 Science Communication in Creative Places
When you think of science communication, you might think of TED talks or museum talks or video talks, or... people giving lectures. It's a lot of people talking. But there's more to sci comm than that. This week host Bethany Brookshire talks to three people who have looked at science communication in places you might not expect it. We'll speak with Mauna Dasari, a graduate student at Notre Dame, about making mammals into a March Madness match. We'll talk with Sarah Garner, director of the Pathologists Assistant Program at Tulane University School of Medicine, who takes pathology instruction out of...
Now Playing: Radiolab

What If?
There's plenty of speculation about what Donald Trump might do in the wake of the election. Would he dispute the results if he loses? Would he simply refuse to leave office, or even try to use the military to maintain control? Last summer, Rosa Brooks got together a team of experts and political operatives from both sides of the aisle to ask a slightly different question. Rather than arguing about whether he'd do those things, they dug into what exactly would happen if he did. Part war game part choose your own adventure, Rosa's Transition Integrity Project doesn't give us any predictions, and it isn't a referendum on Trump. Instead, it's a deeply illuminating stress test on our laws, our institutions, and on the commitment to democracy written into the constitution. This episode was reported by Bethel Habte, with help from Tracie Hunte, and produced by Bethel Habte. Jeremy Bloom provided original music. Support Radiolab by becoming a member today at Radiolab.org/donate.     You can read The Transition Integrity Project's report here.