The FASEB Journal: Fish oil supplementation can slow muscle loss during immobilization

January 10, 2019

A study published in The FASEB Journal demonstrated that dietary supplementation with omega-3 fatty acids (or fish oils) reduced the rate at which young women lost muscle mass during a period of immobilization.

To conduct the study, McGlory and colleagues separated 20 healthy young women into two groups: an omega-3 group and a sunflower oil control group. After consuming the relevant supplement for four weeks, participants had one of their legs immobilized for two weeks using a knee brace. Following the immobilization period, participants returned to normal daily activity for a two-week recovery period.

Researchers measured leg muscle size, mass, strength, and protein synthesis (known to regulate muscle size) before and after immobilization and following the recovery period. In the omega-3 group, the amount of muscle lost during immobilization was significantly lower than that of the control group.

"This novel study suggests that young women may be able to use omega-3 supplementation to slow muscle loss and enhance recovery in situations where one of their limbs is immobilized," explained Chris McGlory, PhD, Diabetes Canada Research Fellow working with Stuart Phillips, PhD, at McMaster University's Department of Kinesiology in Ontario, Canada. "These findings could have implications for muscle recovery following surgery such as ACL reconstruction."

In addition, following two weeks of regular daily activity, the omega-3 group experienced full return of skeletal muscle volume. This finding contradicts previous work in rodents showing inhibited recovery in atrophied muscle by omega-3 fatty acids following hindlimb immobilization.

"The interplay between dietary regimes and concurrent activity levels is not often addressed as squarely as it was in this study," said Thoru Pederson, PhD, Editor-in-Chief of The FASEB Journal.
-end-
This study was supported by a Canadian Institutes of Health Research Award.

The FASEB Journal is published by the Federation of the American Societies for Experimental Biology (FASEB). The world's most cited biology journal according to the Institute for Scientific Information, it has been recognized by the Special Libraries Association as one of the top 100 most influential biomedical journals of the past century. Receive monthly highlights for The FASEB Journal; subscribe at http://www.faseb.org/fjupdate.aspx.

FASEB is composed of 30 societies with more than 130,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and well-being by promoting research and education in biological and biomedical sciences through collaborative advocacy and service to our societies and their members.

Federation of American Societies for Experimental Biology

Related Dietary Supplementation Articles from Brightsurf:

Influence of vitamin D supplementation on a baby's gut microbiome
New research from the CHILD Cohort Study has shed light on the influence of vitamin D supplementation on a baby's developing gut microbiome.

Nitrate supplementation could help breathing and lung clearance in the elderly
New research published today in The Journal of Physiology shows that nitrate improves function in the diaphragm, the muscle involved in coughing and breathing, by improving power.

Vitamin D supplementation linked to potential improvements in blood pressure in children
Overweight and obese vitamin D-deficient children who took a relatively high dose of vitamin D every day for six months had lower blood pressure and improved insulin sensitivity than their peers who took a lower dose.

Common nutrient supplementation may hold the answers to combatting Al
In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease (AD).

Vitamin D supplementation not associated with reduced cardiovascular events
This study, called a meta-analysis, combined the results of 21 randomized clinical trials with about 83,000 patients to look at whether vitamin D supplementation was associated with reduced risk of cardiovascular disease events such as heart attack or stroke.

Follow-up of children for asthma after vitamin D supplementation in moms during pregnancy
This research letter reports on the follow-up of children for asthma whose mothers participated in a randomized clinical trial where they received high-dose vitamin D (2,400 IU/day) during the 24th week of pregnancy or placebo plus the recommended dose of 400 IU/day of vitamin D.

The FASEB Journal: Fish oil supplementation can slow muscle loss during immobilization
A study published in The FASEB Journal demonstrated that dietary supplementation with omega-3 fatty acids (or fish oils) reduced the rate at which young women lost muscle mass during a period of immobilization.

Coenzyme Q10 supplementation on metabolic profiles of patients with chronic kidney disease
This systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted to determine the effects of coenzyme Q10 (CoQ10) supplementation on metabolic profiles of patients diagnosed with chronic kidney disease (CKD).

Dietary fat is good? Dietary fat is bad? Coming to consensus
Which is better, a low-fat/high-carbohydrate diet or a high-fat/low-carbohydrate diet -- or is it the type of fat that matters?

Association of monthly high-dose vitamin D supplementation and cancer risk
Monthly high-dose vitamin D supplementation without calcium for up to four years wasn't associated with reduced cancer risk among adults in New Zealand.

Read More: Dietary Supplementation News and Dietary Supplementation Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.