Muscle-strengthening and conditioning in women associated with reduced risk of diabetes

January 14, 2014

Aerobic exercise is known to prevent type 2 diabetes, and muscle-strengthening alone or in combination with aerobic exercise improves diabetic control among those with diabetes. Although men who weight train have been found to have an associated reduced risk of developing diabetes, whether such an association exists for women has not been established.

In this week's PLOS Medicine, Anders Grøntved (Harvard School of Public Health, Boston, MA, USA, and University of Southern Denmark, Denmark) and colleagues prospectively followed up 99,316 middle-aged and older women for 8 years from the Nurses' Health Study ([NHS] 2000-2008) and Nurses' Health Study II ([NHSII] 2001-2009) who did not have diabetes at baseline, and determined whether their weekly time spent performing resistance exercise, lower intensity muscular conditioning exercises (yoga, stretching, toning), and aerobic moderate and vigorous physical activity (MVPA) reported at baseline and in 2004/2005 was associated wit h a reduced risk of new onset of diabetes.

During the 705,869 person years of follow-up, 3,491 women developed type 2 diabetes. They found that resistance exercise and lower intensity muscular conditioning exercises were both independently associated with a reduced risk for diabetes, even after adjusting for aerobic activity and many other potential confounding factors. Women who engaged in at least 150 min/week of aerobic activity and at least 60 min/week of muscle-strengthening activities had the most substantial risk reduction compared with inactive women (pooled RR = 0.33 [95% CI 0.29-0.38]). Limitations to the study were that physical activity was self-reported by questionnaire, and the study population consisted of nurses with mostly European ancestry.

The authors state, "The findings from our study...suggest that incorporating muscle-strengthening and conditioning activities with aerobic activity according to the current recommendation for physical activity provides substantial benefit for [diabetes] prevention in women." While women who followed current recommendations for both muscle-strengthening and aerobic activity had a substantially reduced risk of diabetes, even those who engaged in muscle-strengthening and aerobic activity at levels lower than currently recommended had a reduced risk of developing diabetes.
-end-
Funding: The study was supported by the National Institutes of Health grants: P01 CA87969, P30 DK46200, CA50385, DK 58845, and UM1 CA176726. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

Citation: Grøntved A, Pan A, Mekary RA, Stampfer M, Willett WC, et al. (2014) Muscle Strengthening and Conditioning Activities and Risk of Type 2 Diabetes: A Prospective Study in Two Cohorts of US Women. PLoS Med 11(1): e1001587. doi:10.1371/journal.pmed.1001587

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001587

Contact:

Todd Datz
Director of News and Online Communications
617-432-8413
tdatz@hsph.harvard.edu

PLOS

Related Diabetes Articles from Brightsurf:

New diabetes medication reduced heart event risk in those with diabetes and kidney disease
Sotagliflozin - a type of medication known as an SGLT2 inhibitor primarily prescribed for Type 2 diabetes - reduces the risk of adverse cardiovascular events for patients with diabetes and kidney disease.

Diabetes drug boosts survival in patients with type 2 diabetes and COVID-19 pneumonia
Sitagliptin, a drug to lower blood sugar in type 2 diabetes, also improves survival in diabetic patients hospitalized with COVID-19, suggests a multicenter observational study in Italy.

Making sense of diabetes
Throughout her 38-year nursing career, Laurel Despins has progressed from a bedside nurse to a clinical nurse specialist and has worked in medical, surgical and cardiac intensive care units.

Helping teens with type 1 diabetes improve diabetes control with MyDiaText
Adolescence is a difficult period of development, made more complex for those with Type 1 diabetes mellitus (T1DM).

Diabetes-in-a-dish model uncovers new insights into the cause of type 2 diabetes
Researchers have developed a novel 'disease-in-a-dish' model to study the basic molecular factors that lead to the development of type 2 diabetes, uncovering the potential existence of major signaling defects both inside and outside of the classical insulin signaling cascade, and providing new perspectives on the mechanisms behind insulin resistance in type 2 diabetes and possibly opportunities for the development of novel therapeutics for the disease.

Tele-diabetes to manage new-onset diabetes during COVID-19 pandemic
Two new case studies highlight the use of tele-diabetes to manage new-onset type 1 diabetes in an adult and an infant during the COVID-19 pandemic.

Genetic profile may predict type 2 diabetes risk among women with gestational diabetes
Women who go on to develop type 2 diabetes after having gestational, or pregnancy-related, diabetes are more likely to have particular genetic profiles, suggests an analysis by researchers at the National Institutes of Health and other institutions.

Maternal gestational diabetes linked to diabetes in children
Children and youth of mothers who had gestational diabetes during pregnancy are at increased risk of diabetes themselves, according to new research published in CMAJ (Canadian Medical Association Journal).

Two diabetes medications don't slow progression of type 2 diabetes in youth
In youth with impaired glucose tolerance or recent-onset type 2 diabetes, neither initial treatment with long-acting insulin followed by the drug metformin, nor metformin alone preserved the body's ability to make insulin, according to results published online June 25 in Diabetes Care.

People with diabetes visit the dentist less frequently despite link between diabetes, oral health
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University's Brody School of Medicine.

Read More: Diabetes News and Diabetes Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.