Nav: Home

Review examines the pros and cons of surgery to reduce the risk of cancer

January 17, 2018

Genetic testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. Many guidelines recommend that gene carriers take certain steps, such as surgery, to reduce their risk of developing cancer. A new BJS (British Journal of Surgery) review explores the quality-of-life consequences of genetic testing and risk-reducing surgery.

The review notes that risk-reducing surgery almost uniformly decreases cancer anxiety and affects patients' quality of life, but it is irreversible and can be associated with short- and long-term side-effects.

"For some hereditary cancer syndromes, risk-reduction surgery increases life expectancy, decreases cancer anxiety, and is associated with improvements in quality of life; however, these procedures are irreversible and can be associated with marked early and late complications," said senior author Dr. Todd Tuttle, of the University of Minnesota, in Minneapolis.
-end-
This study forms part of the BJS Special Issue on Cancer Surgery in the Genomic Era, published online in January 2018. The issue is free to access.

Wiley

Related Genetic Testing Articles:

Genetic testing can pick out men at increased risk of testicular cancer
Testing for large numbers of genetic changes can identify men with over a 10-fold increased risk of testicular cancer, a new study shows.
The Angelina Jolie effect on breast cancer genetic testing
Pop culture icons can influence our fashion choices, dietary habits and brand preferences, but can celebrities also influence our medical decisions?
Studies probe value and impact of direct-to-consumer genetic testing
The latest results from the PGen study were published on Dec.
Prevalence of Ph-like ALL in adults underscores need for genetic testing, clinical trials
International research led by St. Jude Children's Research Hospital shows the high-risk subtype Ph-like ALL accounts for almost 25 percent of ALL cases in adults and may be treatable with available targeted therapies
ASHG Webinar Series: Genetic Testing in Children and Adolescents
This series of three free webinars, intended for primary care providers and specialists who treat children and adolescents, will help fill clinical gaps by teaching best practices in genetic testing.
Should patients be allowed to opt out of routine genetic testing of colorectal tumors?
Health-care providers support routine testing of colorectal tumors to identify more individuals who have the most common genetic condition responsible for such cancers, a new study suggests.
Expanded prenatal genetic testing may increase detection of carrier status for potentially serious genetic conditions
In an analysis that included nearly 350,000 adults of diverse racial and ethnic background, expanded carrier screening for up to 94 severe or profound conditions may increase the detection of carrier status for a variety of potentially serious genetic conditions compared with current recommendations from professional societies, according to a study appearing in the Aug.
New testing method developed for genetic mutation that causes pulmonary hypertension
Pulmonology and genetics experts from two Utah healthcare organizations have collaboratively developed a new diagnostic genomic testing method for a rare form of pulmonary hypertension caused by a genetic mutation they discovered three years ago.
Genetic testing for childhood cancer patients can identify cause and treatment potential
Combined whole exome tumor and blood sequencing in pediatric cancer patients revealed mutations that could help explain the cause of cancer or have the potential to impact clinical cancer care in 40 percent of patients in a study led by researchers from Baylor College of Medicine and Texas Children's Cancer Center.
Dog's recovery at Tufts highlights need for genetic testing, owner vigilance
The remarkable recovery of a dog nursed back to health from the brink of death by Cummings School of Veterinary Medicine at Tufts University highlights the value of a simple genetic test that can help owners determine if their pets are vulnerable to what in most cases is a safe, commonly used drug.

Related Genetic Testing Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Don't Fear Math
Why do many of us hate, even fear math? Why are we convinced we're bad at it? This hour, TED speakers explore the myths we tell ourselves and how changing our approach can unlock the beauty of math. Guests include budgeting specialist Phylecia Jones, mathematician and educator Dan Finkel, math teacher Eddie Woo, educator Masha Gershman, and radio personality and eternal math nerd Adam Spencer.
Now Playing: Science for the People

#517 Life in Plastic, Not Fantastic
Our modern lives run on plastic. It's in the computers and phones we use. It's in our clothing, it wraps our food. It surrounds us every day, and when we throw it out, it's devastating for the environment. This week we air a live show we recorded at the 2019 Advancement of Science meeting in Washington, D.C., where Bethany Brookshire sat down with three plastics researchers - Christina Simkanin, Chelsea Rochman, and Jennifer Provencher - and a live audience to discuss plastics in our oceans. Where they are, where they are going, and what they carry with them. Related links:...