FASEB 3rd International Conference on Retinoids

January 22, 2016

Bethesda, MD - This SRC is the third international retinoid conference. With the discovery of the nuclear retinoid receptors, retinoic acid receptors (RARs) and retinoid X receptors (RXRs), the retinoid field has been implicated in new areas of scientific inquiry including metabolism, metabolic diseases, and neurobiology. The demonstration that RXRs serve as master regulators and signal integrators facilitated transcriptional crosstalk with retinoids and other nuclear receptor superfamily members has broadened interest in retinoid biology and pharmacology. Efforts to study retinoid down-stream signaling effects accelerated discoveries made beyond the nuclear receptors themselves.

Progress has been made in identifying, cloning, and analyzing a family of enzymes critical for the synthesis and degradation of retinoids. Many proteins involved in regulation of retinoid metabolism, homeostasis, and signaling pathways are being explored as potential therapeutic and preventive targets. While retinoid toxicities have limited their application in the clinic, the recent discovery of retinoid receptor selective agonists and antagonists and of multiple novel non-genomic retinoid signaling pathways provided ample opportunities to refine retinoid chemistry and to broaden clinical applications. Receptorselective retinoids retain desired pharmacologic activities, but have reduced toxicities. Exciting examples are the of rexinoids to treat Alzheimer's disease and the physiologic morphogen for T regulatory cells. Timely communication of cutting-edge insights in this field is needed to advance retinoid basic science and biology and to realize public health benefits from this.

FASEB has announced a total of 36 Science Research Conferences (SRC) in 2016. Registration opens January 7, 2016. For more information about an SRC, view preliminary programs, or find a listing of all our 2016 SRCs, please visit http://www.faseb.org/SRC.
Since 1982, FASEB SRC has offered a continuing series of inter-disciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes. In efforts to expand the SRC series, potential organizers are encouraged to contact SRC staff at SRC@faseb.org. Proposal guidelines can be found at http://www.faseb.org/SRC.

FASEB is composed of 30 societies with more than 125,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Federation of American Societies for Experimental Biology

Related Biology Articles from Brightsurf:

Experimental Biology press materials available now
Though the Experimental Biology (EB) 2020 meeting was canceled in response to the COVID-19 outbreak, EB research abstracts are being published in the April 2020 issue of The FASEB Journal.

Structural biology: Special delivery
Bulky globular proteins require specialized transport systems for insertion into membranes.

Cell biology: All in a flash!
Scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich have developed a tool to eliminate essential proteins from cells with a flash of light.

A biology boost
Assistance during the first years of a biology major leads to higher retention of first-generation students.

Cell biology: Compartments and complexity
Ludwig-Maximilians-Universitaet (LMU) in Munich biologists have taken a closer look at the subcellular distribution of proteins and metabolic intermediates in a model plant.

Cell biology: The complexity of division by two
Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have identified a novel protein that plays a crucial role in the formation of the mitotic spindle, which is essential for correct segregation of a full set of chromosomes to each daughter cell during cell division.

Cell biology: Dynamics of microtubules
Filamentous polymers called microtubules play vital roles in chromosome segregation and molecular transport.

The biology of color
Scientists are on a threshold of a new era of color science with regard to animals, according to a comprehensive review of the field by a multidisciplinary team of researchers led by professor Tim Caro at UC Davis.

Kinky biology
How and why proteins fold is a problem that has implications for protein design and therapeutics.

A new tool to decipher evolutionary biology
A new bioinformatics tool to compare genome data has been developed by teams from the Max F.

Read More: Biology News and Biology Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.