Nav: Home

New WHO international fetal growth charts

January 24, 2017

A research article published in PLOS Medicine contributes to the evidence base regarding the use of population charts for detection of fetal growth disorders and how best to determine risk of complications.

In the article, Torvid Kiserud from the University of Bergen, Norway, and colleagues establish the World Health Organization fetal growth charts for head and abdominal circumference, length of the thigh bone, and fetal weight using ultrasound measurements during pregnancy. The researchers included 1,387 healthy women with low-risk pregnancies and unconstrained nutritional and social background from ten countries in Africa, Asia, Europe, and South America, and found that fetal growth showed considerable natural variation, differing significantly between countries, and that fetal growth was to a small extent influenced by maternal age, height, weight, and parity, and by fetal sex. These findings suggest that WHO charts for growth in estimated fetal weight are more suitable for international use than those commonly applied today, but may need to be adjusted for local clinical use to increase their diagnostic and predictive performance.
-end-
Research Article

Funding:

UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Health Organization. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests:

I have read the journal's policy and the authors of this manuscript have the following competing interests: GP is a WHO statistical consultant and has a contract to give statistical support to the Fetal Growth Study. GP has worked with WHO for 15 years and has a relationship with WHO, both paid (contracts) and unpaid. GP is also a good friend of many of the investigators involved in this study. LDP is a Board Member of the Perinatal Quality Foundation, a nonprofit organization related to the Society for Maternal Fetal Medicine. LDP has received research support from General Electric Medical Systems unrelated to fetal growth. LDP also lectures 1 or 2 times per year at an educational meeting supported by General Electric Medical Systems unrelated to fetal growth.

Citation:

Kiserud T, Piaggio G, Carroli G, Widmer M, Carvalho J, Neerup Jensen L, et al. (2017) The World Health Organization Fetal Growth Charts: A Multinational Longitudinal Study of Ultrasound Biometric Measurements and Estimated Fetal Weight. PLoS Med 14(1): e1002220. doi:10.1371/journal.pmed.1002220

Author Affiliations:

Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
Medical Statistics Department, London School of Hygiene &Tropical Medicine, London, United Kingdom
Statistika Consultoria, São Paulo, Brazil
Centro Rosarino de Estudios Perinatales, Rosario, Argentina
Department of Reproductive Health and Research, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research,
Development and Research Training in Human Reproduction, World Health Organization, Geneva, Switzerland
Center of Fetal Medicine, Department of Obstetrics, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas,
Campinas, Brazil
Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, George Washington University,
Washington, District of Columbia, United States of America
Service de Gynecologie Obstetrique, Hôpital Antoine Beclere, AP-HP, Université Paris Sud, Clamart, France
Department for Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
École de Santé Publique, Faculté de Medecine, Université de Kinshasa, Kinshasa, Democratic Republic of the Congo
Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
División de Obstetricia y Ginecología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
Institute of Developmental Sciences, University of Southampton, Southampton, United Kingdom
David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States of America
Center for Fetal Medicine and Women's Ultrasound, Los Angeles, California, United States of America

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002220

PLOS

Related Fetal Growth Articles:

Replicating fetal bone growth process could help heal large bone defects
To treat large gaps in long bones, like the femur, which often can result in amputation, researched developed a process in a rodent model that partially recreates the bone growth process that occurs before birth.
Fetal growth inhibited by cocktail of chemicals in the mother
For the first time, researchers have shown that a combination of perfluorinated substances in the mother significantly inhibits child growth.
Shift work for mothers associated with reduced fetal growth and longer pregnancies
New research published in The Journal of Physiology indicates shift work exposure in mothers can result in reduced fetal growth and longer pregnancies, even when the shift work is only carried out early in pregnancy.
Study finds air purifiers may benefit fetal growth
A new study led by SFU health sciences researchers Prabjit Barn and Ryan Allen reveals fetal growth may improve if pregnant women use portable air purifiers inside their homes.
Joslin researchers report excessive fetal growth despite well-controlled type 1 diabetes
A new study has shown that despite excellent glycemic control and low glycemic variability throughout their pregnancies, women with type 1 diabetes tended to give birth to infants who were large for gestational age.
More Fetal Growth News and Fetal Growth Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Erasing The Stigma
Many of us either cope with mental illness or know someone who does. But we still have a hard time talking about it. This hour, TED speakers explore ways to push past — and even erase — the stigma. Guests include musician and comedian Jordan Raskopoulos, neuroscientist and psychiatrist Thomas Insel, psychiatrist Dixon Chibanda, anxiety and depression researcher Olivia Remes, and entrepreneur Sangu Delle.
Now Playing: Science for the People

#537 Science Journalism, Hold the Hype
Everyone's seen a piece of science getting over-exaggerated in the media. Most people would be quick to blame journalists and big media for getting in wrong. In many cases, you'd be right. But there's other sources of hype in science journalism. and one of them can be found in the humble, and little-known press release. We're talking with Chris Chambers about doing science about science journalism, and where the hype creeps in. Related links: The association between exaggeration in health related science news and academic press releases: retrospective observational study Claims of causality in health news: a randomised trial This...