Combination Nicotine Replacement Therapies Are The Most Effective Means To Quit Smoking

January 29, 1999

(Nicotine nasal spray with nicotine patch for smoking cessation: randomised trial with six year follow up)

Combined methods of nicotine replacement therapy are more effective than using just one, says a study in this week's BMJ. Dr Thorsteinn Blondal and colleagues from National University Hospital in Iceland, along with researchers from Pharmacia and Upjohn in Sweden, found that patients combining the use of nicotine patches with nicotine nasal sprays were twice as likely to still be abstaining from smoking after five years than those who had only used patches.

In their study of 237 smokers over a six year period, the authors found that using a nicotine patch for five months in conjunction with a nicotine nasal spray and then continuing to use the spray only for a further seven months, was the most effective way of stopping smoking. They believe that this is because the patches release nicotine slowly, with the nasal spray delivering nicotine more rapidly, as and when the smoker needs to respond to any smoking urges.

Blondal et al conclude that by providing nicotine in several combinations, abstinence rates after six years can be double those of using a single method of nicotine replacement.


Dr Thorsteinn Blondal, Chest Physician, Reykjavik Health Care Centre, National University Hospital, Iceland


Related Smoking Articles from Brightsurf:

Smoking rates falling in adults, but stroke survivors' smoking rates remain steady
While the rate of Americans who smoke tobacco has fallen steadily over the last two decades, the rate of stroke survivors who smoke has not changed significantly.

What is your risk from smoking? Your network knows!
A new study from researchers at Penn's Annenberg School for Communication found that most people, smokers and non-smokers alike, were nowhere near accurate in their answers to questions about smoking's health effects.

Want to quit smoking? Partner up
Kicking the habit works best in pairs. That's the main message of a study presented today at EuroPrevent 2019, a scientific congress of the European Society of Cardiology (ESC).

Smoking and mortality in Asia
In this analysis of data from 20 studies conducted in China, Japan, South Korea, Singapore, Taiwan and India with more than 1 million participants, deaths associated with smoking continued to increase among men in Asia grouped by the years in which they were born.

Predictors of successfully quitting smoking among smokers registered at the quit smoking clinic at a public hospital in northeastern Malaysia
In the current issue of Family Medicine and Community Health, Nur Izzati Mohammad et al. consider how cigarette smoking is one of the risk factors leading to noncommunicable diseases such as cardiovascular and respiratory system diseases and cancer.

Restaurant and bar smoking bans do reduce smoking, especially among the highly educated
Smoking risk drops significantly in college graduates when they live near areas that have completely banned smoking in bars and restaurants, according to a new study in the American Journal of Epidemiology.

How the UK smoking ban increased wellbeing
Married women with children reported the largest increase in well-being following the smoking bans in the UK in 2006 and 2007 but there was no comparable increase for married men with children.

Smoking study personalizes treatment
A simple blood test is allowing Vanderbilt University Medical Center (VUMC) researchers to determine which patients should be prescribed varenicline (Chantix) to stop smoking and which patients could do just as well, and avoid side effects, by using a nicotine patch.

A biophysical smoking gun
While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons.

A case where smoking helped
A mutation in the hemoglobin of a young woman in Germany was found to cause her mild anemia.

Read More: Smoking News and Smoking Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to