Nav: Home

Chronic kidney disease: Everyone's concern

January 31, 2019

Chronic kidney disease is defined as an abnormality of kidney structure or function that persists for more than three months. It is prevalent, affecting 10.4% of men and 11.8% of women, worldwide [3]. Chronic kidney disease can progress such that between 5.3 and 10.5 million people need kidney replacement therapy in the form of dialysis or transplantation. Although there are many who do not receive these treatments due to lack of resource or financial barriers.

The number of patients affected is growing. The unadjusted incidence rate of renal replacement therapy among all countries represented in the European Renal Registry was 121 per million in 2016 - compared to 117 per million population five years previously in 2011 [4]. This is largely explained by the significant rise in the previous decade by the number of people who suffer from diabetes and hypertension, conditions which can lead to chronic kidney disease. Approximately 425 million adults (20-79 years of age) were living with diabetes in 2017, and this figure will rise further to 629 million by 2045, according to the International Diabetes Federation [5]. The number of people affected by high blood pressure has increased from 594 million in 1975 to over 1.1 billion in 2015 [6]. Diabetes and hypertension are the two most common causes of kidney failure requiring dialysis: one in three patients on dialysis need renal replacement secondary to diabetes. In many instances, the development of diabetes and hypertension is avoidable.

"Against the background of ever-increasing numbers of patients with diabetes and hypertension, there is cause for concern that the incidence of chronic kidney disease, too, will continue to rise", explains ERA-EDTA President Professor Carmine Zoccali. "We are worried that we are only seeing the tip of the iceberg right now. This is why ERA-EDTA has decided to build awareness through education and to provide material to aid prevention."

It is not only the dramatic rise in incidence which is of concern but also the significant risk of ill health and death associated with chronic kidney disease. "Even, if many patients with impaired kidney function do not feel ill over a long period of time, they are at a particularly high risk of many other health outcomes, especially dangerous cardiac complications." A recently published study [7] showed that renal patients are very complex patients - they have more comorbidities and the highest risk of mortality, when compared to patients managed by other specialties including of infectious disease specialists, pulmonologists, hematologists, rheumatologists, gastroenterologists, cardiologists, endocrinologists, and family physicians.

"This means we have the most vulnerable patients, and the incidence of chronic kidney disease is increasing still further. This is why we have to raise our voices and take action now", explains Professor Zoccali. "Prevention of chronic kidney disease must become a general topic in public discourse."
-end-
Press Contact:
ERA-EDTA PRESS OFFICE
Dr Bettina Albers
Jakobstrasse 38
99423 Weimar
Germany
Tel. +49 3643/ 7764-23
Fax +49 3643/ 7764-52

[1] https://web.era-edta.org/uploads/180627-press-era-asn-isn.pdf

[2] http://www.era-edta.org/press/30-01-19-ERA-Card.pdf

[3] GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Jan 10;385(9963):117-71.

[4] ERA-EDTA Registry. Annual Report 2016 and 2011: https://www.era-edta-reg.org/index.jsp?p=14

[5] https://idf.org/52-about-diabetes.html

[6] http://www.bloodpressureuk.org/mediacentre/Newsreleases/1billionpeopleworldwidenowhavehighbloodpressure

[7] Marcello Tonelli et al. Comparison of the Complexity of Patients Seen by Different Medical Subspecialists in a Universal Health Care System. JAMA Netw Open. 2018;1(7): e184852. doi:10.1001/jamanetworkopen.2018.4852

About ERA-EDTA

With more than 11,000 members, the ERA-EDTA ("European Renal Association - European Dialysis and Transplant Association") is one of the biggest nephrology associations worldwide and one of the most important and prestigious European Medical Associations. It supports basic and clinical research in the fields of clinical nephrology, dialysis, renal transplantation and related subjects. It also supports a number of studies as well as research groups and has founded a special "Fellowship Programme" for young investigators as well as grant programmes. In order to involve young nephrologists in all its activities, ERA-EDTA has created the "Young Nephrologists' Platform" (YNP), a very active committee whose board includes members who are 40 years old or younger. In addition, it has established various working groups to promote the collaboration of nephrologists with other medical disciplines (e.g. cardiology, immunology). Furthermore, a "European Renal Best Practice" (ERBP) advisory board was established by the ERA-EDTA to draw up and publish guidelines and position statements. Another important goal of the ERA-EDTA is education: The series of CME courses combined with the annual congress offer an attractive scientific programme to cover the need for continuous medical education for doctors working in the fields of nephrology, dialysis and transplantation. The association's journals, NDT (Nephrology, Dialysis, Transplantation) and CKJ (Clinical Kidney Journal), are currently the leading nephrology journals in Europe; furthermore NDT-Educational is the Society's online educational journal , with free access for all users, as well as being a very important and useful feature of the NDT-Educational "Literature Review". The ERA-EDTA Registry is a large epidemiologic database comparing countries by assessing nephrology practices throughout Europe. ENP, the European Nephrology Portal, is the latest new initiative of ERA-EDTA, where all those interested in the activities of the Society can find everything that is happening, all in one place. Finally, ERA-EDTA is a member of the European Kidney Health Alliance (EKHA), a consortium of patients, nurses and foundations relating to renal issues that actively interacts with the European Parliament. For more information, please visit http://www.era-edta.org

ERA-EDTA

Related Diabetes Articles:

Maternal gestational diabetes linked to diabetes in children
Children and youth of mothers who had gestational diabetes during pregnancy are at increased risk of diabetes themselves, according to new research published in CMAJ (Canadian Medical Association Journal).
Two diabetes medications don't slow progression of type 2 diabetes in youth
In youth with impaired glucose tolerance or recent-onset type 2 diabetes, neither initial treatment with long-acting insulin followed by the drug metformin, nor metformin alone preserved the body's ability to make insulin, according to results published online June 25 in Diabetes Care.
People with diabetes visit the dentist less frequently despite link between diabetes, oral health
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University's Brody School of Medicine.
Diabetes, but not diabetes drug, linked to poor pregnancy outcomes
New research indicates that pregnant women with pre-gestational diabetes who take metformin are at a higher risk for adverse pregnancy outcomes -- such as major birth defects and pregnancy loss -- than the general population, but their increased risk is not due to metformin but diabetes.
New oral diabetes drug shows promise in phase 3 trial for patients with type 1 diabetes
A University of Colorado Anschutz Medical Campus study finds sotagliflozin helps control glucose and reduces the need for insulin in patients with type 1 diabetes.
Can continuous glucose monitoring improve diabetes control in patients with type 1 diabetes who inject insulin
Two studies in the Jan. 24/31 issue of JAMA find that use of a sensor implanted under the skin that continuously monitors glucose levels resulted in improved levels in patients with type 1 diabetes who inject insulin multiple times a day, compared to conventional treatment.
Complications of type 2 diabetes affect quality of life, care can lead to diabetes burnout
T2D Lifestyle, a national survey by Health Union of more than 400 individuals experiencing type 2 diabetes (T2D), reveals that patients not only struggle with commonly understood complications, but also numerous lesser known ones that people do not associate with diabetes.
A better way to predict diabetes
An international team of researchers has discovered a simple, accurate new way to predict which women with gestational diabetes will develop type 2 diabetes after delivery.
The Lancet Diabetes & Endocrinology: Older Americans with diabetes living longer without disability, US study shows
Older Americans with diabetes born in the 1940s are living longer and with less disability performing day to day tasks than those born 10 years earlier, according to new research published in The Lancet Diabetes & Endocrinology journal.
Reverse your diabetes -- and you can stay diabetes-free long-term
A new study from Newcastle University, UK, has shown that people who reverse their diabetes and then keep their weight down remain free of diabetes.
More Diabetes News and Diabetes Current Events

Top Science Podcasts

We have hand picked the top science podcasts of 2019.
Now Playing: TED Radio Hour

Risk
Why do we revere risk-takers, even when their actions terrify us? Why are some better at taking risks than others? This hour, TED speakers explore the alluring, dangerous, and calculated sides of risk. Guests include professional rock climber Alex Honnold, economist Mariana Mazzucato, psychology researcher Kashfia Rahman, structural engineer and bridge designer Ian Firth, and risk intelligence expert Dylan Evans.
Now Playing: Science for the People

#541 Wayfinding
These days when we want to know where we are or how to get where we want to go, most of us will pull out a smart phone with a built-in GPS and map app. Some of us old timers might still use an old school paper map from time to time. But we didn't always used to lean so heavily on maps and technology, and in some remote places of the world some people still navigate and wayfind their way without the aid of these tools... and in some cases do better without them. This week, host Rachelle Saunders...
Now Playing: Radiolab

Dolly Parton's America: Neon Moss
Today on Radiolab, we're bringing you the fourth episode of Jad's special series, Dolly Parton's America. In this episode, Jad goes back up the mountain to visit Dolly's actual Tennessee mountain home, where she tells stories about her first trips out of the holler. Back on the mountaintop, standing under the rain by the Little Pigeon River, the trip triggers memories of Jad's first visit to his father's childhood home, and opens the gateway to dizzying stories of music and migration. Support Radiolab today at Radiolab.org/donate.