Choice of anesthesia may affect breast cancer metastases

January 31, 2020

STONY BROOK, NY, January 29, 2020 - A new study led by Stony Brook University Cancer Center researchers to be published in Nature Communications suggests that the choice of anesthesia may change the metastatic process of breast cancer by affecting the cytokine and microenvironment.

Jun Lin, MD, PhD, of the Department of Anesthesiology in the Renaissance School of Medicine at Stony Brook University, and colleagues found that sevoflurane anesthesia leads to more metastatic burden in the lung after breast tumor resecting surgery than propofol in laboratory models.

The study findings may serve as a guide to design clinical trials for clinicians to optimize anesthesia choice for breast cancer surgery in order to achieve best long-term outcomes.
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Stony Brook University, widely regarded as a SUNY flagship, is going beyond the expectations of what today's public universities can accomplish. Since its founding in 1957, this young university has grown to become one of only four University Center campuses in the State University of New York (SUNY) system with over 26,000 students, more than 2,700 faculty members and 18 NCAA Division I athletic programs. Our faculty have earned numerous prestigious awards, including the Nobel Prize, Pulitzer Prize, Indianapolis Prize for animal conservation, Abel Prize and the inaugural Breakthrough Prize in Mathematics. The University offers students an elite education with an outstanding return on investment: U.S.News & World Report ranks Stony Brook among the top 40 public universities in the nation. Its membership in the Association of American Universities (AAU) places Stony Brook among the top 62 research institutions in North America. As part of the management team of Brookhaven National Laboratory, the University joins a prestigious group of universities that have a role in running federal R&D labs. Stony Brook University fuels Long island's economic growth. Its impact on the Long island economy amounts to $7.38 billion in increased output. Our state, country and world demand ambitious ideas, imaginative solutions and exceptional leadership to forge a better future for all. The students, alumni, researchers and faculty of Stony Brook University are prepared to meet this challenge.

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