Nav: Home

Working it out: Researchers find exercise may help fight depression in seniors

February 07, 2019

The benefits of exercise are widely known but kinesiologists at McMaster University have for the first time found that physical activity may help fight depression in seniors by stimulating muscle-generated mood boosters.

The findings, published in the American Journal of Physiology--Cell Physiology, reveal that the underlying mechanisms which make us feel good when we exercise persist into old age and highlight the importance of staying active.

"A previous study demonstrated these mechanisms in healthy young adults, however, it was unknown whether the muscle deterioration which accompanies aging would preclude older adults from achieving similar exercise-induced benefits," explains David Allison, lead author on the study and a postdoctoral fellow in McMaster's Department of Kinesiology.

"This could have important implications concerning the use of exercise as a treatment or a preventative strategy for depression in seniors," he says.

Little is known about the relationship between skeletal muscle and mental health, or how exercise impacts this relationship.

Earlier research has shown that physical activity may help to 'turn on' genes within skeletal muscle which can then influence the key metabolic pathways that ultimately promote mood-enhancing chemicals, such as serotonin, within the brain.

Muscle loss is a common problem in the elderly which may restrict that pathway and therefore increase the risk for depression, says Allison.

For the study, a group of healthy men, aged 65 and over, followed a 12-week protocol of high-intensity interval training (HIIT) on a stationary bike once a week combined with bi-weekly strength training sessions.

Researchers analyzed blood samples and changes to muscle and determined that three months of exercise was enough to enhance gene expression within the skeletal muscle.

"Even individuals who are already metabolically healthy--with good weight, good blood pressure and blood sugar levels--need to prioritize regular physical activity to maintain or improve upon their mental health," says Allison. "We have shown such benefits are still achievable in old age and further emphasize the importance of maintaining an active lifestyle."

In the future, researchers hope to explore the relationship between mental health and exercise among the clinically depressed to see if similar biochemical changes can be achieved.
-end-


McMaster University

Related Depression Articles:

Why stress doesn't always cause depression
Rats susceptible to anhedonia, a core symptom of depression, possess more serotonin neurons after being exposed to chronic stress, but the effect can be reversed through amygdala activation, according to new research in JNeurosci.
Which comes first: Smartphone dependency or depression?
New research suggests a person's reliance on his or her smartphone predicts greater loneliness and depressive symptoms, as opposed to the other way around.
Depression breakthrough
Major depressive disorder -- referred to colloquially as the 'black dog' -- has been identified as a genetic cause for 20 distinct diseases, providing vital information to help detect and manage high rates of physical illnesses in people diagnosed with depression.
CPAP provides relief from depression
Researchers have found that continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA) can improve depression symptoms in patients suffering from cardiovascular diseases.
Post-natal depression in dads linked to depression in their teenage daughters
Fathers as well as mothers can experience post-natal depression -- and it is linked to emotional problems for their teenage daughters, new research has found.
Being overweight likely to cause depression, even without health complications
A largescale genomic analysis has found the strongest evidence yet that being overweight causes depression, even in the absence of other health problems.
Don't let depression keep you from exercising
Exercise may be just as crucial to a depression patient's good health as finding an effective antidepressant.
Having an abortion does not lead to depression
Having an abortion does not increase a woman's risk for depression, according to a new University of Maryland School of Public Health-led study of nearly 400,000 women.
Mother's depression might do the same to her child's IQ
Roughly one in 10 women in the United States will experience depression, according to the Centers for Disease Control and Prevention.
Teenage depression linked to father's depression
Adolescents whose fathers have depressive symptoms are more likely to experience symptoms of depression themselves, finds a new Lancet Psychiatry study led by UCL researchers.
More Depression News and Depression Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Teaching For Better Humans 2.0
More than test scores or good grades–what do kids need for the future? This hour, TED speakers explore how to help children grow into better humans, both during and after this time of crisis. Guests include educators Richard Culatta and Liz Kleinrock, psychologist Thomas Curran, and writer Jacqueline Woodson.
Now Playing: Science for the People

#556 The Power of Friendship
It's 2020 and times are tough. Maybe some of us are learning about social distancing the hard way. Maybe we just are all a little anxious. No matter what, we could probably use a friend. But what is a friend, exactly? And why do we need them so much? This week host Bethany Brookshire speaks with Lydia Denworth, author of the new book "Friendship: The Evolution, Biology, and Extraordinary Power of Life's Fundamental Bond". This episode is hosted by Bethany Brookshire, science writer from Science News.
Now Playing: Radiolab

Dispatch 3: Shared Immunity
More than a million people have caught Covid-19, and tens of thousands have died. But thousands more have survived and recovered. A week or so ago (aka, what feels like ten years in corona time) producer Molly Webster learned that many of those survivors possess a kind of superpower: antibodies trained to fight the virus. Not only that, they might be able to pass this power on to the people who are sick with corona, and still in the fight. Today we have the story of an experimental treatment that's popping up all over the country: convalescent plasma transfusion, a century-old procedure that some say may become one of our best weapons against this devastating, new disease.   If you have recovered from Covid-19 and want to donate plasma, national and local donation registries are gearing up to collect blood.  To sign up with the American Red Cross, a national organization that works in local communities, head here.  To find out more about the The National COVID-19 Convalescent Plasma Project, which we spoke about in our episode, including information on clinical trials or plasma donation projects in your community, go here.  And if you are in the greater New York City area, and want to donate convalescent plasma, head over to the New York Blood Center to sign up. Or, register with specific NYC hospitals here.   If you are sick with Covid-19, and are interested in participating in a clinical trial, or are looking for a plasma donor match, check in with your local hospital, university, or blood center for more; you can also find more information on trials at The National COVID-19 Convalescent Plasma Project. And lastly, Tatiana Prowell's tweet that tipped us off is here. This episode was reported by Molly Webster and produced by Pat Walters. Special thanks to Drs. Evan Bloch and Tim Byun, as well as the Albert Einstein College of Medicine.  Support Radiolab today at Radiolab.org/donate.