Sonoporation: Underlying mechanisms and applications in cellular regulation

February 09, 2021

Announcing a new article publication for BIO Integration journal. In this review article the authors Yue Li, Zhiyi Chen and Shuping Ge from First Affiliated Hospital of University of South China, Hengyang, China and Tower Health and Drexel University, Philadelphia, PA, USA summarize current state of the art applications of microbubble-cell interactions and sonoporation effects to cellular functions.

Ultrasound combined with microbubble-mediated sonoporation has been applied to enhance drug or gene intracellular delivery. Sonoporation leads to the formation of openings in the cell membrane, triggered by ultrasound-mediated oscillations and destruction of microbubbles. Multiple mechanisms are involved in the occurrence of sonoporation, including ultrasonic parameters, microbubbles size, and the distance of microbubbles to cells. Recent advances are beginning to extend applications through the assistance of contrast agents, which allow ultrasound to connect directly to cellular functions such as gene expression, cellular apoptosis, differentiation, and even epigenetic reprogramming.
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Article reference: Yue Li, Zhiyi Chen and Shuping Ge, Sonoporation: Underlying Mechanisms and Applications in Cellular Regulation. BIO Integration, 2021, https://doi.org/10.15212/bioi-2020-0028

BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.

As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at: https://mc04.manuscriptcentral.com/bioi

Please visit http://www.bio-integration.org to learn more about the journal.

Editorial Board: https://bio-integration.org/editorial-board/

Please visit http://www.bio-integration.org to learn more about the journal.

Editorial Board: https://bio-integration.org/editorial-board/

BIOI is available on the IngentaConnect platform and at the BIO Integrationwebsite .

Submissions may be made using ScholarOne .

There are no author submission or article processing fees.

Follow BIOI on Twitter @JournalBio; Facebook and LinkedIn .

ISSN 2712-0074
eISSN 2712-0082Keywords: Microbubble, multidisciplinary, reprogramming, sonoporation, ultrasound

Compuscript Ltd

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