Compounds from apples may boost brain function

February 11, 2021

Natural compounds found in apples and other fruits may help stimulate the production of new brain cells, which may have implications for learning and memory, according to a .

Chemical substances found in plants, so-called phytonutrients, such as resveratrol in red grapes or epigallo-catechin-3-gallate (EGCG) in green tea, can have positive effects on different parts of the body including the brain. Researchers
Tara Louise Walker, University of Queensland, Brisbane, Australia and Gerd Kempermann, German Center for Neurodegenerative Diseases, Dresden, Germany, and colleagues found that high concentrations of phytonutrients from apples stimulate the generation of new neurons, a process called neurogenesis. The study showed that laboratory-grown stem cells from adult mouse brains generated more neurons and were protected from cell death when quercetin or dihydroxybezoic acid (DHBA), phytonutrients commonly found in apples, were added to the cultures. Subsequent tests in mice showed that in distinct structures of the adult brain associated with learning and memory, stem cells multiplied and generated more neurons when the mice were given high doses of quercetin or DHBA. The effects on neurogenesis were comparable to effects seen after physical exercise, a known stimulus for neurogenesis. This study suggests that natural compounds in fruits, such as quercetin, DHBA and potentially others, may act in synergy to promote neurogenesis and brain function when given in high concentrations. Future studies will be required to determine if these and other phytonutrients can enhance learning and cognitive function in animal models and in humans.
-end-


International Society for Stem Cell Research

Related Memory Articles from Brightsurf:

Memory of the Venus flytrap
In a study to be published in Nature Plants, a graduate student Mr.

Memory protein
When UC Santa Barbara materials scientist Omar Saleh and graduate student Ian Morgan sought to understand the mechanical behaviors of disordered proteins in the lab, they expected that after being stretched, one particular model protein would snap back instantaneously, like a rubber band.

Previously claimed memory boosting font 'Sans Forgetica' does not actually boost memory
It was previously claimed that the font Sans Forgetica could enhance people's memory for information, however researchers from the University of Warwick and the University of Waikato, New Zealand, have found after carrying out numerous experiments that the font does not enhance memory.

Memory boost with just one look
HRL Laboratories, LLC, researchers have published results showing that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by 20% after only one viewing of the episode, compared to controls.

VR is not suited to visual memory?!
Toyohashi university of technology researcher and a research team at Tokyo Denki University have found that virtual reality (VR) may interfere with visual memory.

The genetic signature of memory
Despite their importance in memory, the human cortex and subcortex display a distinct collection of 'gene signatures.' The work recently published in eNeuro increases our understanding of how the brain creates memories and identifies potential genes for further investigation.

How long does memory last? For shape memory alloys, the longer the better
Scientists captured live action details of the phase transitions of shape memory alloys, giving them a better idea how to improve their properties for applications.

A NEAT discovery about memory
UAB researchers say over expression of NEAT1, an noncoding RNA, appears to diminish the ability of older brains to form memories.

Molecular memory can be used to increase the memory capacity of hard disks
Researchers at the University of Jyväskylä have taken part in an international British-Finnish-Chinese collaboration where the first molecule capable of remembering the direction of a magnetic above liquid nitrogen temperatures has been prepared and characterized.

Memory transferred between snails
Memories can be transferred between organisms by extracting ribonucleic acid (RNA) from a trained animal and injecting it into an untrained animal, as demonstrated in a study of sea snails published in eNeuro.

Read More: Memory News and Memory Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.