Have migraine? Bigger waistline may be linked

February 12, 2009

SEATTLE - Overweight people who are between the ages of 20 and 55 may have a higher risk of experiencing migraine headaches, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

For the study, abdominal obesity was measured by waist circumference or the total size around the waist. Total body obesity was also measured. This was calculated using the body mass index, a measurement related to weight and height. Researchers looked at 22,211 people who were asked to report whether they suffered from either migraine or severe headaches.

The study found that age, gender and the way that body fat is distributed affected the risk of migraine. Those who were 20 to 55 years of age and who had larger waistlines were more likely to have migraine attacks, on average, than people of the same age who had smaller waistlines. About 37 percent of women between the ages of 20󈞣 who had excess fat around the belly reported migraine, compared to 29 percent without excess belly fat.

In men 20 to 55 years old, 20 percent of those with abdominal obesity reported migraine as compared to 16 percent of those without abdominal obesity. However in women 20 to 55 years of age with excess belly fat, the odds of migraine went up 1.3 times after adjusting for heart disease risk factors and for total body obesity.

After the age of 55, total body obesity was not associated with migraine in men or women. However, in women older than 55 years with large waistlines the odds of migraine actually decreased.

"These results, while still in the early stages, suggest that losing weight in the stomach area may be beneficial for younger people who experience migraine and especially so for women," said study author B. Lee Peterlin, DO, of Drexel University College of Medicine in Philadelphia, PA, and a member of the American Academy of Neurology.

"Men and women have body tissue distributed in different ways. After puberty women show more fatty tissue deposits in the hip and thigh area while men predominantly have more fatty tissue in the belly region. After menopause, women show more fatty tissue in the belly area as well. For some diseases, including heart disease and diabetes, excess fat around the waistline appears to be a stronger risk factor than total body obesity," Peterlin said.
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The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as multiple sclerosis, restless legs syndrome, Alzheimer's disease, narcolepsy, and stroke.

For more information about the American Academy of Neurology, visit www.aan.com.

The AAN 61st Annual Meeting, the world's largest gathering of neurology professionals, takes place April 25 to May 2, 2009, in Seattle. Visit www.aan.com/am for more information.

Editor's Note: Study authors are available for interviews. Please contact Jenine Anderson, janderson@aan.com or Jay Mac Bride, jmacbride@aan.com.

To access 2009 AAN Annual Meeting abstracts available February 25, 2009, visit http://www.aan.com/go/science/abstracts.

Late-breaking abstracts will be featured in press release at the 2009 AAN Annual Meeting in Seattle.

Media Contacts:
Jenine Anderson, (651) 695-2789, janderson@aan.com
Jay Mac Bride, (651) 695-2795, jmacbride@aan.com

American Academy of Neurology

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