Nav: Home

Efforts are needed to tap into the potential of nutraceuticals

February 13, 2018

A growing demand exists for nutraceuticals, which seem to reside in the grey area between pharmaceuticals and food. The products are thought to provide medical or health benefits "beyond the diet, but before the drugs". A new review published in the British Journal of Clinical Pharmacology looks at the potential of nutraceuticals, stressing the need for a proper definition of nutraceuticals and clear regulations to ensure their safety.

In the review article, a team led by Ettore Novellino, PhD and Antonello Santini, PhD, of the University of Napoli Federico II in Italy, states that nutraceuticals with proven efficacy and health benefits substantiated by clinical data could be used as powerful tools to prevent and treat medical conditions, especially in individuals who may not yet be eligible for conventional pharmaceutical drugs. Therefore, it is of utmost importance to have a proper and unequivocal definition of nutraceuticals, to conduct clinical studies on their safety and efficacy, and to have standardized regulations for their use. In addition, nutraceuticals require a specific classification apart from food supplements and pharmaceuticals.

The authors propose the following definition for nutraceuticals: the phytocomplex of a vegetable or the pool of secondary metabolites from an animal. Both are concentrated and administered in a pharmaceutical form and are capable of providing beneficial health effects, including the prevention and/or treatment of a disease.

"Nutraceuticals, in the collective imagination of the consumer, tend to be confused and wrongly identified with many other products available on the market on the basis of potential health benefits," said Dr. Novellino. "An evaluation of the safety, the mechanism of action, and the effectiveness of nutraceuticals--and substantiating this with clinical data--is the central point that differentiates nutraceuticals from food supplements."

Dr. Santini added that the growing demand and interest in nutraceuticals justifies the need for a restructuring of the entire regulatory framework that differentiates nutraceuticals from food supplements. "We propose a regulatory system that is similar to the one used for drugs, which is more rigorous and more complex than the one commonly accepted for food supplements," he said. "It is important for consumer protection that national authorities and regulatory agencies require manufacturers to provide data to support any claim in the labels of products when the term nutraceutical is used."
-end-
Full citation: "Nutraceuticals: opening the debate for a regulatory framework." Antonello Santini, Silvia Miriam Cammarata, Giacomo Capone, Angela Ianaro, Giancarlo Tenore, Luca Pani, and Ettore Novellino. British Journal of Clinical Pharmacology. Published Online: February 13, 2018, DOI: 10.1111/bcp.13496.

URL Upon Publication: http://doi.wiley.com/10.1111/bcp.13496

Author Contact: To arrange an interview with the author, please contact Prof. Antonello Santini at asantini@unina.it or 0039 81 2539317.

About the Journal: The British Journal of Clinical Pharmacology has the primary goal of publishing high quality research papers on all aspects of drug action in humans. The journal has a wide readership, bridging the medical profession, clinical research and the pharmaceutical industry, and is published monthly. It is owned by the British Pharmacological Society and published by Wiley. The journal's current Impact Factor is 3.83 (Thomson Reuters Science Citation Index).

About The British Pharmacological Society

The British Pharmacological Society is a charity with a mission to promote and advance the whole spectrum of pharmacology. Founded in 1931, it is now a global community at the heart of pharmacology, with over 3,500 members from more than 60 countries worldwide. The Society leads the way in the research and application of pharmacology around the world through its scientific meetings, educational resources and peer-reviewed journals: the British Journal of Clinical Pharmacology, Pharmacology Research & Perspectives, and the British Journal of Pharmacology, which includes the Concise Guide to PHARMACOLOGY, featuring open access overviews of the key properties of over 1,700 human therapeutic targets and their drugs, and links to http://www.guidetopharmacology.org.

Press Office: T. +44 (0) 207 239 0180 E. nick.courtney@bps.ac.uk

About Wiley

Wiley, a global research and learning company, helps people and organizations develop the skills and knowledge they need to succeed. Our online scientific, technical, medical, and scholarly journals, combined with our digital learning, assessment and certification solutions help universities, learned societies, businesses, governments and individuals increase the academic and professional impact of their work. For more than 210 years, we have delivered consistent performance to our stakeholders. The company's website can be accessed at http://www.wiley.com.

Wiley

Related Drugs Articles:

Using drugs for different diseases than initially intended for
Thousands of drugs have the potential to be effective against other diseases than they were developed for.
Virtual development of real drugs
systemsDock is a new, free on-line resource that makes screening for drugs faster and more accurate.
Migraine drugs underused
New research shows that more migraines could be safely treated with drugs that are known to constrict blood vessels.
Why cancer drugs can't take the pressure
A major reason why cancer drugs fail is that they cannot penetrate the high-pressure environment of solid tumors.
Designing better drugs
A new strategy for engineering protein fusions -- to make specific cell-targeted drugs without side effects -- could enable a safer, more potent class of protein drugs.
Why synthetic drugs are as scary as you think (video)
Synthetic drugs such as 'bath salts,' 'K2' or 'Spice' have made unsettling headlines lately, with reports of violent, erratic behavior and deaths after people have used the substances.
Using old drugs to treat new viruses
A group of drugs already in everyday use to treat psychosis or depression may also be used to defeat deadly and emerging viruses, according to new research led by the University of Leeds.
'Metal' drugs to fight cancer
What is the mechanism of action of metal-based chemotherapy drugs (the most widely used for treating common cancers like testicular or ovarian cancer)?
Using superlatives in the media for cancer drugs
The use of superlatives to describe cancer drugs in news articles as 'breakthrough,' 'revolutionary,' 'miracle' or in other grandiose terms was common even when drugs were not yet approved, had no clinical data or not yet shown overall survival benefits, according to an article published online by JAMA Oncology.
Seeking a better way to design drugs
With a three-year, $346,000 award from the National Institutes of Health, a research team at Worcester Polytechnic Institute.

Related Drugs Reading:

Buzzed: The Straight Facts About the Most Used and Abused Drugs from Alcohol to Ecstasy (Fully Revised and Updated Fourth Edition)
by Cynthia Kuhn Ph.D. (Author), Scott Swartzwelder Ph.D. (Author), Wilkie Wilson Ph.D. (Author), Jeremy Foster (Foreword), Leigh Heather Wilson (Foreword)

The fourth edition of the essential, accessible source for understanding how drugs work and their effects on body and behavior.

A bestseller in its three previous editions, Buzzed is now revised and updated with the most recent discoveries about drugs. It includes new information about biological and behavioral changes in addiction, the prescription-drug abuse epidemic, distinctive drug effects on the adolescent brain, and trends from synthetic cannabinoids to e-cigarettes. “Lively, highly informative, unbiased, [and] thorough” (Addiction Research &... View Details


Nursing2019 Drug Handbook (Nursing Drug Handbook)
by Lippincott (Author)

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product.

THE #1 Drug Guide for nurses & other clinicians…always dependable, always up to date!
  
Look for these outstanding featuresCompletely updated nursing-focused drug monographs featuring over 3,650 generic, brand-name, and combination drugs in an easy A-to-Z format37 brand-new FDA-approved drugs in this edition, including 33 complete monographs—tabbed and... View Details


Davis's Drug Guide for Nurses
by April Hazard Vallerand PhD RN FAAN (Author), Cynthia A. Sanoski BS PharmD FCCP BCPS (Author)

SAFETY FIRST!


Davis’s Drug Guide for Nurses®, Fifteenth Edition delivers all of the information you need to administer medications safely across the lifespan—well-organized monographs for hundreds of generic and thousands of trade-name drugs.


BONUS!

FREE DIGITAL ACCESS


www.DrugGuide.com


SAFETY FIRST!


Davis’s Drug Guide for Nurses®, Sixteenth Edition delivers all of the information you need to administer medications safely across the lifespan—well-organized monographs for hundreds of generic and thousands of trade-name drugs.


BONUS!

FREE DIGITAL ACCESS


www.DrugGuide.com


View Details


2018 Lippincott Pocket Drug Guide for Nurses
by Amy M. Karch MSN RN (Author)

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product.

The 2018 Lippincott Pocket Drug Guide for Nurses provides current, vital drug information “in a nutshell.” Based on the popular Lippincott Nursing Drug Guide by Amy Karch, this handy pocket guide by the same author gives essential information on over 2,000 medications in an easy-access A-to-Z format. The “mini” drug monographs include generic and trade names,... View Details


Drugs: From Discovery to Approval
by Rick Ng (Author)

The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. 

Concise and easy to read, Drugs: From Discovery to Approval, Third Edition quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. The... View Details


Illegal Drugs: A Complete Guide to their History, Chemistry, Use, and Abuse
by Paul Gahlinger (Author)

Does Ecstasy cause brain damage? Why is crack more addictive than cocaine? What questions regarding drugs are legal to ask in a job interview? When does marijuana possession carry a greater prison sentence than murder?

Illegal Drugs is the first comprehensive reference to offer timely, pertinent information on every drug currently prohibited by law in the United States.  It includes their histories, chemical properties and effects, medical uses and recreational abuses, and associated health problems, as well as addiction and treatment information.

Additional survey chapters... View Details


Drug Information Handbook Dentistry
by Richard L., Ed. Wynn (Author)

View Details

Best Science Podcasts 2018

We have hand picked the best science podcasts for 2018. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Attention Please
In an age of constant information and infinite distractions, how can we pay more attention to our ... attention? This hour, TED speakers explore the battle for our awareness during the digital age. Guests include sociologist Zeynep Tufekci, podcast host Manoush Zomorodi, neuroscientist Amishi Jha, designer Tristan Harris, and computer scientist Jaron Lanier.
Now Playing: Science for the People

#475 Mother Nature is Trying to Kill You (Rebroadcast)
This week, we're learning how deadly and delightful our planet and its ecosystem can be. We're joined by biologist Dan Riskin, co-host of Discovery Canada's Daily Planet, to talk about his book "Mother Nature Is Trying to Kill You: a Lively Tour Through the Dark Side of the Natural World." And we'll talk to astronomer and author Phil Plait about Science Getaways, his company that offers educational vacation experiences for science lovers.