Nav: Home

Patients with chagas disease are often infected with an intestinal parasite

February 14, 2018

Chagas Disease (caused by the parasite Trypanosoma cruzi) and strongyloidiasis (caused by the helminth S. stercoralis) are neglected tropical diseases that share a similar epidemiological burden and result in chronic infections with high morbidity and mortality.

In this retrospective study, the authors evaluated the association between Trypanosoma cruzi infection and strongyloidiasis in a cohort of Latin American migrants screened for both infections in the Hospital Clinic at Barcelona between January 2013 and April 2015. The results obtained with 361 individuals show that 14% of them were positive for strongyloidiasis and 49% were positive for T. cruzi. Factors associated with T. cruzi infection included being of Bolivian origin, coming from a a rural area and having lived in an adobe house. A higher percentage of patients with strongyloidiasis was infected by T. cruzi, and viceversa. The statistical analysis shows that T. cruzi infection was associated with a two-fold increase in the odds of strongyloidiasis in Latin American migrants attending a tropical diseases unit, even after adjusting for other epidemiological variables.

"Both diseases are strongly influenced by socioeconomic factors and poor healthcare systems" says Jose Muñoz, ISGlobal researcher and coordinator of the study.

"We have already demonstrated the cost-benefit of performing systemic Chagas screening in asymptomatic Latino American adults living in Europe" explains Joaquim Gascon. Given the high prevalence of strongyloidiasis in T. cruzi infected patients, the authors recommend implementing a combined screening program for both infections among Latin American adults living in Europe.
-end-


Barcelona Institute for Global Health (ISGlobal)

Related Chagas Disease Articles:

Deaths from Chagas disease under-reported
Chagas disease, affecting millions of people in Central and South America, is classified as one of the 17 most important neglected diseases by the World Health Organization.
First large-scale survey of Chagas disease in the United States confirms that the 'silent killer' is a major public health challenge for the country
A study of almost 5,000 Latin American-born residents of Los Angeles County found that 1.24 percent tested positive for Chagas disease, a parasitic infection that can cause life-threatening heart damage if not treated early.
Findings support role of vascular disease in development of Alzheimer's disease
Among adults who entered a study more than 25 years ago, an increasing number of midlife vascular risk factors, such as obesity, high blood pressure, diabetes, high cholesterol and smoking, were associated with elevated levels of brain amyloid (protein fragments linked to Alzheimer's disease) later in life, according to a study published by JAMA.
Dietary factors associated with substantial proportion of deaths from heart disease, stroke, and disease
Nearly half of all deaths due to heart disease, stroke, and type 2 diabetes in the US in 2012 were associated with suboptimal consumption of certain dietary factors, according to a study appearing in the March 7 issue of JAMA.
Study links changes in oral microbiome with metabolic disease/risk for dental disease
A team of scientists from The Forsyth Institute and the Dasman Diabetes Institute in Kuwait have found that metabolic diseases, which are characterized by high blood pressure, high blood sugar, and obesity -- leads to changes in oral bacteria and puts people with the disease at a greater risk for poor oral health.
Targets and patented drugs for chemotherapy of Chagas disease
Chagas disease is a parasitic infection typically spread by triatomine vectors, affecting millions of people all over Latin America.
IDRI contributes to first point-of-care Chagas disease diagnostic for US
With Chagas disease becoming more prevalent in the United States, a diagnostic to quickly and easily detect infection is needed.
Seroprevalence and disease burden of chagas disease in south Texas
A paper published in PLOS Neglected Diseases led by researchers at the National School of Tropical Medicine at Baylor College of Medicine suggests that the disease burden in southern Texas is much higher than previously thought.
Fatty liver disease contributes to cardiovascular disease and vice versa
For the first time, researchers have shown that a bi-directional relationship exists between fatty liver disease and cardiovascular disease.
Resveratrol reverses heart damage in mice with Chagas disease
Resveratrol is the antioxidant found in red wine and famous as a food supplement capable of mimicking the effects of exercise and low calorie diets in the heart.

Related Chagas Disease Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Jumpstarting Creativity
Our greatest breakthroughs and triumphs have one thing in common: creativity. But how do you ignite it? And how do you rekindle it? This hour, TED speakers explore ideas on jumpstarting creativity. Guests include economist Tim Harford, producer Helen Marriage, artificial intelligence researcher Steve Engels, and behavioral scientist Marily Oppezzo.
Now Playing: Science for the People

#524 The Human Network
What does a network of humans look like and how does it work? How does information spread? How do decisions and opinions spread? What gets distorted as it moves through the network and why? This week we dig into the ins and outs of human networks with Matthew Jackson, Professor of Economics at Stanford University and author of the book "The Human Network: How Your Social Position Determines Your Power, Beliefs, and Behaviours".