Nav: Home

Study details link between obesity, carbs and esophageal cancer

February 25, 2008

Cleveland, Ohio - February 25, 2008 - Cases of esophageal cancer (adenocarcinoma) in the U.S. have risen in recent decades from 300,000 cases in 1973 to 2.1 million in 2001 at age-adjusted rates. A new study published in The American Journal of Gastroenterology shows that these rates in the U.S. closely mirrored trends of increased carbohydrate intake and obesity from 1973-2001.

The study illustrates what may be a public heath concern as the composition of U.S. diets changes and total carbohydrate and refined carbohydrate intakes increase. Obesity is a risk factor for many types of cancer, and a diet that includes a high percentage of calories from refined carbohydrates is a common contributor to obesity. Carbohydrates were also unique in that no other studied nutrients were found to correlate with esophageal cancer rates.

The causes of esophageal cancer remain largely unknown. Despite recent advances in treatment, esophageal cancer has a poor prognosis. The five-year rate of survival for esophageal cancer remains below 20 percent and is the eighth-leading cause of cancer related death in American men.

"If we can reverse the trends in refined carbohydrate intake and obesity in the U.S., we may be able to reduce the incidence of esophageal cancer," says Dr. Li Li, senior author of the study.
-end-
This study is published in The American Journal of Gastroenterology. Media wishing to receive a PDF of this article may contact medicalnews@bos.blackwellpublishing.net.

Dr. Li Li is an Assistant Professor in the Department of Family Medicine and Case Comprehensive Cancer Center at Case Western Reserve University/University Hospitals Health System. Dr. Li can be reached for questions at lxl62@cwru.edu.

The American Journal of Gastroenterology is the official publication of the American College of Gastroenterology, and the #1 clinical journal in gastroenterology. The journal brings a broad-based, interdisciplinary approach to the study of gastroenterology, including articles reporting on current observations, research results, methods of treatment, drugs, epidemiology, and other topics relevant to clinical gastroenterology. For more information, please visit www.blackwellpublishing.com/ajg.

The American College of Gastroenterology (ACG) was founded in 1932 to advance the scientific study and medical practice of diseases of the gastrointestinal (GI) tract. The College promotes the highest standards in medical education and is guided by its commitment to meeting the individual and collective needs of clinical GI practitioners. For more information, please visit www.acg.gi.org.

Blackwell Publishing Ltd.

Related Obesity Articles:

Obesity is in the eye of the beholder
Doctors have a specific definition of what it means to be overweight or obese, but in the social world, gender, race and generation matter a lot for whether people are judged as 'thin enough' or 'too fat.'
Type 2 diabetes and obesity -- what do we really know?
Social and economic factors have led to a dramatic rise in type 2 diabetes and obesity around the world.
Three in 4 don't know obesity causes cancer
Three out of four (75 percent) people in the UK are unaware of the link between obesity and cancer, according to a new Cancer Research UK report published today.
Obesity on the rise in Indonesia
Obesity is on the rise in Indonesia, one of the largest studies of the double burden of malnutrition in children has revealed.
Obesity rates are not declining in US youth
A clear and significant increase in obesity continued from 1999 through 2014, according to an analysis of data on United States children and adolescents age 2 to 19 years.
How does the environment affect obesity?
Researchers will be examining how agricultural and food processing practices may affect brown fat activity directly or indirectly.
Obesity Day to highlight growing obesity epidemic in Europe
The growing obesity epidemic, which is predicted to affect more than half of all European citizens by 2030, will be the focus of European Obesity Day to be held on May 21.
Understanding obesity from the inside out
Researchers developed a new laboratory method that allowed them to identify GABA as a key player in the complex brain processes that control appetite and metabolism.
Epigenetic switch for obesity
Obesity can sometimes be shut down.
Immunological Aspects of Obesity
This FASEB Conference focuses on the interactions between obesity and immune cells, focusing in particular on how inflammation in various organs influences obesity and obesity-related complications.

Related Obesity Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Anthropomorphic
Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#SB2 2019 Science Birthday Minisode: Mary Golda Ross
Our second annual Science Birthday is here, and this year we celebrate the wonderful Mary Golda Ross, born 9 August 1908. She died in 2008 at age 99, but left a lasting mark on the science of rocketry and space exploration as an early woman in engineering, and one of the first Native Americans in engineering. Join Rachelle and Bethany for this very special birthday minisode celebrating Mary and her achievements. Thanks to our Patreons who make this show possible! Read more about Mary G. Ross: Interview with Mary Ross on Lash Publications International, by Laurel Sheppard Meet Mary Golda...