Nav: Home

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer

February 27, 2017

CANCER RESEARCH UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer.

The work will be carried out by scientists at Cancer Research UK's Drug Discovery Unit at The University of Manchester, after the new family of compounds was identified using HitGen's leading technology platform. This involved screening vast DNA encoded libraries, containing many hundreds of millions of small molecules with drug-like properties synthesized on chemically diverse scaffolds. A number of new small molecule leads for this important therapeutic target in lung cancer nominated by Cancer Research UK were revealed.

This is the first license taken through the ongoing collaboration between CRT, Cancer Research UK's Manchester Institute Drug Discovery Group and HitGen, who are eligible for milestone payments as the project progresses.

Dr Jin Li, CEO of HitGen, said: "We're delighted to announce this significant project milestone. We look forward to seeing the progress made by the Cancer Research UK Manchester Institute."

Dr Donald Ogilvie, head of drug discovery at the Cancer Research UK Manchester Institute at The University of Manchester, said: "We're very pleased to work with HitGen to find promising leads against these more difficult targets that may otherwise not be developed."

"As part of the Cancer Research UK Lung Cancer Centre of Excellence, we're determined to get new lung cancer treatments to patients quicker. Identifying this promising candidate drug offers the potential to help boost survival from this devastating disease."
-end-


Cancer Research UK

Related Lung Cancer Articles:

AI helps to fight against lung cancer
Lung cancer has been the leading cause of cancer-related deaths in 2015 in United States.
Free lung-cancer screening in the Augusta area finds more than double the cancer rate of previous screenings
The first year of free lung cancer screening in the Augusta, Ga., area found more than double the rate seen in a previous large, national study as well as a Massachusetts-based screening for this No.
Antioxidants and lung cancer risk
An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer.
Lung cancer may go undetected in kidney cancer patients
Could lung cancer be hiding in kidney cancer patients? Researchers with the Harold C.
Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer.
More Lung Cancer News and Lung Cancer Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Anthropomorphic
Do animals grieve? Do they have language or consciousness? For a long time, scientists resisted the urge to look for human qualities in animals. This hour, TED speakers explore how that is changing. Guests include biological anthropologist Barbara King, dolphin researcher Denise Herzing, primatologist Frans de Waal, and ecologist Carl Safina.
Now Playing: Science for the People

#534 Bacteria are Coming for Your OJ
What makes breakfast, breakfast? Well, according to every movie and TV show we've ever seen, a big glass of orange juice is basically required. But our morning grapefruit might be in danger. Why? Citrus greening, a bacteria carried by a bug, has infected 90% of the citrus groves in Florida. It's coming for your OJ. We'll talk with University of Maryland plant virologist Anne Simon about ways to stop the citrus killer, and with science writer and journalist Maryn McKenna about why throwing antibiotics at the problem is probably not the solution. Related links: A Review of the Citrus Greening...