Nav: Home

FASEB Science Research Conference: Mechanism and Regulation of Prokaryotic Transcription

February 28, 2017

This SRC will focus on the process of transcription in prokaryotes, from structure/function investigations to transcription networks and system level regulation. In all organisms, controlling the process of transcription is fundamental to gene expression, gene regulation, and development. RNA polymerase, which transcribes genomic DNA into RNA, is the complex protein machine that performs transcription. Additional factors that alter initiation, elongation, or termination of transcription program an amazing variety of developmental pathways. Biochemical and genetic investigations of transcription regulation have a long history of revealing the myriad ways that gene expression can be controlled. In recent years this work has been augmented by the availability of atomic-level structures of prokaryotic and eukaryotic RNA polymerases and transcription factors in combination with systems-wide profiling of gene regulatory events. Together this work has revealed that many similar structure-function relationships underlie the workings of the transcriptional machinery from the simplest bacterium to a human cell. Attendees can expect exciting sessions on RNA polymerase structural biology, mechanisms that control initiation, elongation, and termination, regulation of transcription in pathogens, RNA-based control, transcriptional networks, and connections between cell topology and gene expression.

Since its inception in 1991, this SRC has been held biannually at the Vermont Academy in Saxtons River, VT. It is now considered to be the premier meeting in the field of prokaryotic transcription, and we are very proud of the fact that there is so much collegiality and a broad age range at this conference. Approximately half of the speakers are chosen from submitted abstracts and the lively poster sessions are always well-attended by all participants. There will be many opportunities for participants to meet new friends and foster new collaborations.
-end-


Federation of American Societies for Experimental Biology

Related Rna Articles:

How RNA formed at the origins of life
A single process for how a group of molecules called nucleotides were made on the early Earth, before life began, has been suggested by a UCL-led team of researchers.
RNA and longevity: Discovering the mechanisms behind aging
Korean researchers suggests that NMD-mediated RNA quality control is critical for longevity in the roundworm called C. elegans, a popularly used animal for aging research.
Don't kill the messenger RNA
Success of new protein-making therapy for hemophilia opens door for treating many other diseases.
RNA modification important for brain function
Researchers at the Institute of Molecular Biology (IMB) and Johannes Gutenberg University Mainz (JGU) have shown that a new way of regulating genes is vital for the activity of the nervous system.
Atlas of the RNA universe takes shape
In the last few years, small snippets of RNA, which may have played a key role in the planet's earliest flickering of life, have been uncovered and examined in great detail.
Punching cancer with RNA knuckles
Researchers achieved an unexpected eye-popping reduction of ovarian cancer during successful tests of targeted nanohydrogel delivery in vivo in mice.
Gatekeeping proteins to aberrant RNA: You shall not pass
Berkeley Lab researchers found that aberrant strands of genetic code have telltale signs that enable gateway proteins to recognize and block them from exiting the nucleus.
Short RNA molecules mapped in single cell
Researchers at Karolinska Institutet have measured the absolute numbers of short, non-coding, RNA sequences in individual embryonic stem cells.
Watching RNA fold
New technology takes a nucleotide-resolution snapshot of RNA as it is folding, which could lead to discoveries in biology, gene expression, and disease.
Bacteria: Third RNA binding protein identified
Pathogenic bacteria use small RNA molecules to adapt to their environment.

Related Rna Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Bias And Perception
How does bias distort our thinking, our listening, our beliefs... and even our search results? How can we fight it? This hour, TED speakers explore ideas about the unconscious biases that shape us. Guests include writer and broadcaster Yassmin Abdel-Magied, climatologist J. Marshall Shepherd, journalist Andreas Ekström, and experimental psychologist Tony Salvador.
Now Playing: Science for the People

#513 Dinosaur Tails
This week: dinosaurs! We're discussing dinosaur tails, bipedalism, paleontology public outreach, dinosaur MOOCs, and other neat dinosaur related things with Dr. Scott Persons from the University of Alberta, who is also the author of the book "Dinosaurs of the Alberta Badlands".