Classical subject underpins new biomedical advancesMarch 16, 2005
The ancient art of physiology -- the study of how the body works and how to repair it when things go wrong--has seen an upsurge in importance as it now plays a key role in the understanding of how genes work to support the human body.
At his inaugural lecture on Thursday (17 March), University of Edinburgh Professor Michael J. Shipston will say that our ability to isolate, manipulate and visualise gene products in cells and whole animals has revolutionized the understanding of the body and its functions. This in turn has caused a rise in demand for scientists with physiological training, to fully exploit these advances.
He will say: "This classical subject was described by Aristotle as the study of the whole organism and its component parts. It is now at the forefront of current biomedical advances as it seeks to understand how the catalogue of our genes, the human genome, is exploited to generate and maintain the human body."
Michael J. Shipston, Professor of Physiology and Director of the Centre for Integrative Physiology at the University, will discuss the importance of communication within and between cells of the body, in order to keep its 30kg of cells warm, fed and able to reproduce in 20 litres of water. To achieve this, cells need to overcome a major paradox -- the transfer of information, nutrients and waste products across fatty cell membranes which are designed to limit the transfer of these important molecules in order to keep the cell's environment separate from that of its neighbours.
He will say that art influences his approach to science, as by visualising the body's life processes, such as cells releasing hormones or single molecules in motion, he is able to obtain new insights into the basic processes which make the body work.
Physiology and the Art of Communication by Professor Michael Shipston, College of Medicine and Veterinary Medicine, University of Edinburgh: Thursday, 17 March 2005 in the Anatomy Lecture Theatre, Medical School, Teviot Place at 5.15pm
University of Edinburgh
Related Genes Articles:
An international team of researchers has found, for the first time, seven risk genes for insomnia.
By screening thousands of individuals, an international team led by researchers of the Max Planck Institute for Psycholinguistics, the University of Bristol, the Broad Institute and the iPSYCH consortium has provided new insights into the relationship between genes that confer risk for autism or schizophrenia and genes that influence our ability to communicate during the course of development.
The Neanderthals disappeared about 30,000 years ago, but little pieces of them live on in the form of DNA sequences scattered through the modern human genome.
Many of the characteristics that make up a person's face, such as nose size and face width, stem from specific genetic variations, reports John Shaffer of the University of Pittsburgh in Pennsylvania, and colleagues, in a study published on Aug.
Using rats carefully bred to either drink large amounts of alcohol or to spurn it, researchers at Indiana and Purdue universities have identified hundreds of genes that appear to play a role in increasing the desire to drink alcohol.
For a long time dismissed as 'junk DNA,' we now know that also the regions between the genes fulfill vital functions.
Research led by Dr. Keiji Tanimoto from the University of Tsukuba, Japan, has brought us closer to understanding the mechanisms underlying the phenomenon of genomic imprinting.
The DNA in our cells is folded into millions of small packets, like beads on a string, allowing our two-meter linear DNA genomes to fit into a nucleus of only about 0.01 mm in diameter.
A new approach developed by Harvard geneticist George Church, Ph.D., can help uncover how tandem gene circuits dictate life processes, such as the healthy development of tissue or the triggering of a particular disease, and can also be used for directing precision stem cell differentiation for regenerative medicine and growing organ transplants.
Researchers at Duke University have demonstrated a new way to activate genes with light, allowing precisely controlled and targeted genetic studies and applications.
Related Genes Reading:
The Gene: An Intimate History
by Siddhartha Mukherjee (Author)
THE #1 NEW YORK TIMES BESTSELLER
A New York Times Notable Book
A Washington Post and Seattle Times Best Book of the Year
From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle).
“Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for... View Details
Dirty Genes: A Breakthrough Program to Treat the Root Cause of Illness and Optimize Your Health
by Ben Lynch ND. (Author)
Instant National Bestseller
After suffering for years with unexplainable health issues, Dr. Ben Lynch discovered the root cause—“dirty” genes. Genes can be “born dirty” or merely “act dirty” in response to your environment, diet, or lifestyle—causing lifelong, life-threatening, and chronic health problems, including cardiovascular disease, autoimmune disorders, anxiety, depression, digestive issues, obesity, cancer, and diabetes.
Based on his own experience and successfully helping thousands of clients, Dr. Lynch shows you how to identify and... View Details
Lewin's GENES XII
by Jocelyn E. Krebs (Author), Elliott S. Goldstein (Author), Stephen T. Kilpatrick (Author)
Long considered the quintessential molecular biology textbook, for decades Lewin's GENES has provided the most modern presentation to this transformative and dynamic science. Now in its twelfth edition, this classic text continues to lead with new information and cutting-edge developments, covering gene structure, sequencing, organization, and expression. Leading scientists provide revisions and updates in their respective areas of study offering readers current research and relevant information on the rapidly changing subjects in molecular biology. No other text offers a broader... View Details
Genetics: From Genes to Genomes, 5th edition
by Leland H. Hartwell (Author), Michael L. Goldberg (Author), Janice A. Fischer (Author), Leroy Hood (Author), Charles F. Aquadro (Author)
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.
Users who purchase Connect Plus receive access to the full online ebook version of the textbook as well as SmartBook. View Details
Genes: A Very Short Introduction (Very Short Introductions)
by Jonathan Slack (Author)
In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime. Slack also explores issues such as the role of genetic heritability and IQ as well as the changes that... View Details
Dirty Genes Diet: 50 Meals For Positive Gene Expression-Turn Bad Genes Off And Good Genes On
by Paul Bergmann (Author)
50 Meals For Positive Gene Expression-Turn Bad Genes Off And Good Genes On You may think of your genetic code, your unique sequence of DNA that is passed down from your parents, as a predetermined lottery of whether you will be thin, smart, or develop diabetes. But more important than your genes in determining your health and how you age is how your genes interact with your dietary and other lifestyle choices. Even if you carry a “bad” gene, you can influence whether you turn that gene on or off. The interaction between your genes and nutrients, called nutrigenomics, is a two way street:... View Details
Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being
by Deepak Chopra M.D. (Author), Rudolph E. Tanzi Ph.D. (Author)
The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled.
"You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting."
Learning how to shape your gene activity is... View Details
Living with Our Genes: The Groundbreaking Book About the Science of Personality, Behavior, and Genetic Destiny
by Dean H. Hamer (Author), Peter Copeland (Author)
"A lucid, thought-provoking account of the case for 'nature' as a determinant of personality."—Peter D. Kramer, Author of Listening to Prozac and Should You Leave?
Nowhere is the nature-nurture controversy being more arduously tested than in the labs of world-renowned molecular scientist Dean Hamer, whose cutting-edge research has indisputably linked specific genes to behavioral traits, such as anxiety, thrill-seeking, and homosexuality. The culmination of that research is this provocative book, Living with Our Genes. In it, Dr. Hamer reveals that much of... View Details
Barefoot Gen, Vol. 1: A Cartoon Story of Hiroshima
by Keiji Nakazawa (Author)
This harrowing story of Hiroshima was one of the original Japanese manga series. New and unabridged, this is an all-new translation of the author's first-person experiences of Hiroshima and its aftermath, is a reminder of the suffering war brings to innocent people. Its emotions and experiences speak to children and adults everywhere. Volume one of this ten-part series details the events leading up to and immediately following the atomic bombing of Hiroshima. View Details
The Stranger in My Genes: A Memoir
by Bill Griffeth (Author)
Bill Griffeth, longtime genealogy buff, takes a DNA test that has an unexpected outcome: “If the results were correct, it meant that the family tree I had spent years documenting was not my own.” Bill undertakes a quest to solve the mystery of his origins, which shakes his sense of identity. As he takes us on his journey, we learn about choices made by his ancestors, parents, and others—and we see Bill measure and weigh his own difficult choices as he confronts the past. View Details