Fifteenth Anniversary Of The Multicenter AIDS Cohort Study

March 17, 1999

The Multicenter AIDS Cohort (MACS), a four-institution, 15-year research project that has tracked the occurrence and consequences of human immunodefiency virus (HIV) in the lives of a group of 5,000 homosexual and bisexual men since the early nineteen-eighties, will celebrate its fifteenth anniversary on March 31, 1999. Because AIDS in the early eighties was found largely in homosexual men, the MACS was set up to gather epidemiological evidence and to try and understand the full spectrum of the AIDS related diseases. More than 5,000 volunteers came forward to join the study.

Of the cohort in Baltimore, 109 have come to every clinic visit for the past 15 years. More than 600 articles have been generated from the MACS research ranging from the role of CD4 lymphocyte counts and viral load in predicting AIDS, to average incubation time, to the genetics of AIDS - why some people handle the virus so much better than others. Over the years the MACS has provided critical data about early events in the course of HIV infection and about conversion to AIDS. The study also looked at factors that might be involved in transmitting the infection and helped identify the most important ones. Finally, the MACS has built up a large repository of biologic specimens with detailed epidemiologic data for investigators, which have been used in a wide variety of studies by AIDS researchers nationwide.

The MACS sites are the Johns Hopkins School of Public Health in Baltimore, Maryland; Northwestern University Medical School in Chicago, Illinois; University of California Schools of Public Health and Medicine in Los Angeles; and University of Pittsburgh Graduate School of Public Health in Pittsburgh, Pennsylvania.

Please contact the public affairs office at the Johns Hopkins School of Public Health if you would like to talk to study volunteers or researchers. Our phone number is 410-955-6878 or email to kwojciec@jhsph.edu.
-end-


Johns Hopkins University Bloomberg School of Public Health

Related HIV Articles from Brightsurf:

BEAT-HIV Delaney collaboratory issues recommendations measuring persistent HIV reservoirs
Spearheaded by Wistar scientists, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

The Lancet HIV: Study suggests a second patient has been cured of HIV
A study of the second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene, finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy, according to a case report published in The Lancet HIV journal and presented at CROI (Conference on Retroviruses and Opportunistic Infections).

Children with HIV score below HIV-negative peers in cognitive, motor function tests
Children who acquired HIV in utero or during birth or breastfeeding did not perform as well as their peers who do not have HIV on tests measuring cognitive ability, motor function and attention, according to a report published online today in Clinical Infectious Diseases.

Efforts to end the HIV epidemic must not ignore people already living with HIV
Efforts to prevent new HIV transmissions in the US must be accompanied by addressing HIV-associated comorbidities to improve the health of people already living with HIV, NIH experts assert in the third of a series of JAMA commentaries.

The Lancet HIV: Severe anti-LGBT legislations associated with lower testing and awareness of HIV in African countries
This first systematic review to investigate HIV testing, treatment and viral suppression in men who have sex with men in Africa finds that among the most recent studies (conducted after 2011) only half of men have been tested for HIV in the past 12 months.

The Lancet HIV: Tenfold increase in number of adolescents on HIV treatment in South Africa since 2010, but many still untreated
A new study of more than 700,000 one to 19-year olds being treated for HIV infection suggests a ten-fold increase in the number of adolescents aged 15 to 19 receiving HIV treatment in South Africa, according to results published in The Lancet HIV journal.

Starting HIV treatment in ERs may be key to ending HIV spread worldwide
In a follow-up study conducted in South Africa, Johns Hopkins Medicine researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.

NIH HIV experts prioritize research to achieve sustained ART-free HIV remission
Achieving sustained remission of HIV without life-long antiretroviral therapy (ART) is a top HIV research priority, according to a new commentary in JAMA by experts at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

The Lancet HIV: PrEP implementation is associated with a rapid decline in new HIV infections
Study from Australia is the first to evaluate a population-level roll-out of pre-exposure prophylaxis (PrEP) in men who have sex with men.

Researchers date 'hibernating' HIV strains, advancing BC's leadership in HIV cure research
Researchers have developed a novel way for dating 'hibernating' HIV strains, in an advancement for HIV cure research.

Read More: HIV News and HIV Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.