Nav: Home

New brain reading technology could help the development of brainwave-controlled devices

March 20, 2020

A new method to accurately record brain activity at scale has been developed by researchers at the Crick, Stanford University and UCL. The technique could lead to new medical devices to help amputees, people with paralysis or people with neurological conditions such as motor neurone disease.

The research in mice, published in Science Advances, developed an accurate and scalable method to record brain activity across large areas, including on the surface and in deeper regions simultaneously.

Using the latest in electronics and engineering techniques, the new device combines silicon chip technology with super-slim microwires, up to 15-times thinner than a human hair. The wires are so thin they can be placed deep in the brain without causing significant damage. Alongside its ability to accurately monitor brain activity, the device could also be used to inject electrical signals into precise areas of the brain.

"This technology provides the basis for lots of exciting future developments beyond neuroscience research. It could lead to tech that can pass a signal from the brain to a machine, for example helping those with amputations to control a prosthetic limb to shake a hand or stand up. It could also be used to create electrical signals in the brain when neurons are damaged and aren't firing themselves, such as in motor neurone disease," says Andreas Schaefer, group leader in the neurophysiology of behaviour laboratory at the Crick and professor of neuroscience at UCL.

When the device is connected to a brain, electrical signals from active neurons travel up the nearby microwires to a silicon chip, where the data is processed and analysed showing which areas of the brain are active.

The researchers ensured the design of the device allows it to be easily scaled depending on the size of the animal, with a few hundred wires for a mouse to over 100,000 for larger mammals. This is a key feature of the device as it means it holds potential, in the future, to be scaled for use with humans.

Mihaly Kollo, co-lead author, postdoc at the Crick's neurophysiology of behaviour laboratory and senior research associate at UCL, says: "One of the great challenges in recording brain activity, especially in deeper regions, is how to get the wires, called electrodes, in position without causing a lot of tissue damage or bleeding. Our method overcomes this by using electrodes that are sufficiently thin.

"Another challenge is recording the activity of many neurons that are that are distributed in layers with complex shapes in the three-dimensional space. Again, our method provides a solution as the wires can be readily arranged into any 3D shape."

The technology described in the study is also the basis for a fully integrated brain computer interface system that is being developed by Paradromics, a company founded by Matthew Angle, one of the authors of this paper. The Texas-based company is working to develop a medical device platform that will improve the lives of people with critical diseases, including paralysis, sensory impairment and drug resistant neuropsychiatric diseases.
-end-


The Francis Crick Institute

Related Neurons Articles:

The first 3D map of the heart's neurons
An interdisciplinary research team establishes a new technological pipeline to build a 3D map of the neurons in the heart, revealing foundational insight into their role in heart attacks and other cardiac conditions.
Mapping the neurons of the rat heart in 3D
A team of researchers has developed a virtual 3D heart, digitally showcasing the heart's unique network of neurons for the first time.
How to put neurons into cages
Football-shaped microscale cages have been created using special laser technologies.
A molecule that directs neurons
A research team coordinated by the University of Trento studied a mass of brain cells, the habenula, linked to disorders like autism, schizophrenia and depression.
Shaping the social networks of neurons
Identification of a protein complex that attracts or repels nerve cells during development.
With these neurons, extinguishing fear is its own reward
The same neurons responsible for encoding reward also form new memories to suppress fearful ones, according to new research by scientists at The Picower Institute for Learning and Memory at MIT.
How do we get so many different types of neurons in our brain?
SMU (Southern Methodist University) researchers have discovered another layer of complexity in gene expression, which could help explain how we're able to have so many billions of neurons in our brain.
These neurons affect how much you do, or don't, want to eat
University of Arizona researchers have identified a network of neurons that coordinate with other brain regions to influence eating behaviors.
Mood neurons mature during adolescence
Researchers have discovered a mysterious group of neurons in the amygdala -- a key center for emotional processing in the brain -- that stay in an immature, prenatal developmental state throughout childhood.
Connecting neurons in the brain
Leuven researchers uncover new mechanisms of brain development that determine when, where and how strongly distinct brain cells interconnect.
More Neurons News and Neurons Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Our Relationship With Water
We need water to live. But with rising seas and so many lacking clean water – water is in crisis and so are we. This hour, TED speakers explore ideas around restoring our relationship with water. Guests on the show include legal scholar Kelsey Leonard, artist LaToya Ruby Frazier, and community organizer Colette Pichon Battle.
Now Playing: Science for the People

#569 Facing Fear
What do you fear? I mean really fear? Well, ok, maybe right now that's tough. We're living in a new age and definition of fear. But what do we do about it? Eva Holland has faced her fears, including trauma and phobia. She lived to tell the tale and write a book: "Nerve: Adventures in the Science of Fear".
Now Playing: Radiolab

Uncounted
First things first: our very own Latif Nasser has an exciting new show on Netflix. He talks to Jad about the hidden forces of the world that connect us all. Then, with an eye on the upcoming election, we take a look back: at two pieces from More Perfect Season 3 about Constitutional amendments that determine who gets to vote. Former Radiolab producer Julia Longoria takes us to Washington, D.C. The capital is at the heart of our democracy, but it's not a state, and it wasn't until the 23rd Amendment that its people got the right to vote for president. But that still left DC without full representation in Congress; D.C. sends a "non-voting delegate" to the House. Julia profiles that delegate, Congresswoman Eleanor Holmes Norton, and her unique approach to fighting for power in a virtually powerless role. Second, Radiolab producer Sarah Qari looks at a current fight to lower the US voting age to 16 that harkens back to the fight for the 26th Amendment in the 1960s. Eighteen-year-olds at the time argued that if they were old enough to be drafted to fight in the War, they were old enough to have a voice in our democracy. But what about today, when even younger Americans are finding themselves at the center of national political debates? Does it mean we should lower the voting age even further? This episode was reported and produced by Julia Longoria and Sarah Qari. Check out Latif Nasser's new Netflix show Connected here. Support Radiolab today at Radiolab.org/donate.