TMJ: Stem cell biology and engineering toward clinical translation

March 21, 2012

Tampa, Fla., USA - On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy. The symposium is co-sponsored by the Craniofacial Biology, Mineralized Tissue and Neuroscience Scientific Research Groups of the International Association for Dental Research. The presentations in this multidisciplinary symposium will represent broad and yet comprehensive approaches toward the understanding of the origin, homeostasis, differentiation, hormonal regulation and bioengineering of temporomandibular joint (TMJ) tissues.

TMJ disorders are a poorly understood cluster of diseases, ranging from neuromuscular pain to severe forms of arthritis. Recently, stem/progenitor cells have been identified in TMJ disc and condyle, with potential origin from neural crest cells in development. Putative TMJ stem/progenitor cells are subjected to local, hormonal and other systemic factors in homeostasis in multiple processes that warrant better elucidation. In parallel, there is an acute demand in the clinical community for the regeneration of various TMJ components, including the disc, condyle, synovium and the mandible.

This symposium will not only provide new aspects of a timely and under-studied subject of TMJ biology and therapeutics, but also use TMJ as a model for the study of other dental and craniofacial structures and diseases.
-end-
This is a summary of sequence #87 titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" which will feature abstracts to be presented by M. Embree, M. Detamore, A. Le and S. Kapila at the Annual Meeting of the American Association for Dental Research. This symposium will take place at 8 a.m. on Friday, March 23, 2012, in room 10 of the Tampa Convention Center.

About the American Association for Dental Research

The American Association for Dental Research (AADR), headquartered in Alexandria, Va., is a nonprofit organization with nearly 4,000 members in the United States. Its mission is: (1) to advance research and increase knowledge for the improvement of oral health; (2) to support and represent the oral health research community; and (3) to facilitate the communication and application of research findings. AADR is the largest Division of the International Association for Dental Research (IADR).

To learn more about the AADR, visit www.aadronline.org.

International & American Associations for Dental Research

Related Engineering Articles from Brightsurf:

Re-engineering antibodies for COVID-19
Catholic University of America researcher uses 'in silico' analysis to fast-track passive immunity

Next frontier in bacterial engineering
A new technique overcomes a serious hurdle in the field of bacterial design and engineering.

COVID-19 and the role of tissue engineering
Tissue engineering has a unique set of tools and technologies for developing preventive strategies, diagnostics, and treatments that can play an important role during the ongoing COVID-19 pandemic.

Engineering the meniscus
Damage to the meniscus is common, but there remains an unmet need for improved restorative therapies that can overcome poor healing in the avascular regions.

Artificially engineering the intestine
Short bowel syndrome is a debilitating condition with few treatment options, and these treatments have limited efficacy.

Reverse engineering the fireworks of life
An interdisciplinary team of Princeton researchers has successfully reverse engineered the components and sequence of events that lead to microtubule branching.

New method for engineering metabolic pathways
Two approaches provide a faster way to create enzymes and analyze their reactions, leading to the design of more complex molecules.

Engineering for high-speed devices
A research team from the University of Delaware has developed cutting-edge technology for photonics devices that could enable faster communications between phones and computers.

Breakthrough in blood vessel engineering
Growing functional blood vessel networks is no easy task. Previously, other groups have made networks that span millimeters in size.

Next-gen batteries possible with new engineering approach
Dramatically longer-lasting, faster-charging and safer lithium metal batteries may be possible, according to Penn State research, recently published in Nature Energy.

Read More: Engineering News and Engineering Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.