Men have a higher level of function before and after total knee replacement surgery

March 24, 2015

LAS VEGAS--While men and women have similar levels of improvement following total knee replacement (TKR) surgery, men have higher levels of function before and after TKR, according to new research presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

According to the Agency for Healthcare Research and Quality, more than 600,000 knee replacements are performed in the U.S. each year. In 2012, 393,345 women and 237,896 men underwent TKR, most often to alleviate the pain and immobility associated with late-stage arthritis. While research has looked at the anatomic differences between the knees of men and women, the higher levels of arthritis in women versus men, and the utilization of TKR among men and women, there has been little study on how gender influences the level of function before and after surgery.

In this study, researchers identified and studied 287 TKR patients at seven different institutions between 2005 and 2007. All of the patients were between the ages of 21 and 80 at the time of surgery and a body mass index <40 g>

At five years post-surgery, implant survival was 100 percent for men and 99.1 percent for women. Range of motion also was nearly identical between genders. Functional scores were consistently higher for the men versus women: preoperatively, 57.1 versus 51; postoperatively at six weeks, 63.7 versus 51.5; at three months, 83.1 versus 74.3; at two years, 90 vs. 81.6; at five years, 90.1 vs. 82.9; and at seven years, 96 vs. 79.5. Men also recovered faster within the six week recovery time after surgery; however, both genders had almost identical improvement in mean knee score function (improvement from presurgical levels) at five years.

"Our data supports that while both genders benefit from TKR, men have higher levels of function and activity both prior to and after TKR compared to women," said lead study authors Jeffrey J. Cherian, DO and Michael A. Mont, MD. "These functional outcome differences are most likely due to many factors (including biologic/genetic) and highlight the need for further research related to the role of gender of both the patient and the surgeon in the decision making process of TKR, sex-based biological differences in functional recovery capacity, and whether sex/gender based pre- and postoperative rehabilitation protocols are warranted."
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