Nav: Home

Despite reductions in infectious disease mortality in US, diarrheal disease deaths on the rise

March 27, 2018

SEATTLE - Deaths from infectious diseases have declined overall in the United States over the past three decades. However, the rates of decline varied significantly by counties, according to a new scientific study.

The number of deaths attributed to diarrheal diseases has increased substantially as well. While that number is relatively small (about 8,000), diarrhea-related deaths increased in nearly all counties from 1980 to 2014 and were ranked the second-leading cause of all infectious disease mortality behind lower respiratory infections (LRIs) such as pneumonia and bronchitis.

The full study, published today in JAMA, can be found here:

http://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2018.2089

More detailed study findings are available in interactive data visualization tools at https://vizhub.healthdata.org/subnational/usa

LRI-related deaths accounted for more than three-quarters of all infectious disease deaths in 2014. A substantial proportion of those is likely due to the effects of an aging population.

"Our findings are relevant in examining local differences, which often are masked by national or state-level averages," said Dr. Charbel El Bcheraoui, lead author on the study and Assistant Professor at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. "These large disparities are due to variation in risk factors such as alcohol, drugs, or smoking, as well as socioeconomic factors and access to quality medical care. They underscore the need to monitor the transmission of infectious diseases carefully and to help prevent outbreaks."

Numerous countries within a corridor of states between Missouri and Maine were among the highest in the nation in 2014 for diarrhea-related deaths, with rates nearly 4 per 100,000 people.

Nationally, the death rate from infectious diseases decreased about 19%, from 42 to 34 deaths per 100,000 people, from 1980 to 2014.

Six major infectious disease groups were included in this analysis and each accounted for at least 1% of all deaths from infectious diseases nationally from 1980 to 2014. In addition to LRI, diarrheal diseases, and HIV/AIDS, these groups were hepatitis, meningitis, and tuberculosis. Deaths from chronic hepatitis B and chronic hepatitis C were excluded from the hepatitis grouping.

MORTALITY RATES PER 100,000 PEOPLE IN 2014
"Worst" county / "Best" county / US overall

    Lower respiratory infections: East Feliciana Parish, LA (87.7) / Collier County, FL (7.2) / US (26.9)

    Diarrheal diseases: Ross County, OH (6.1) / Kalawao County, HI, and Maui County, HI (both 0.5) / US (2.4)

    HIV/AIDS: Union County, FL (54.9) / Saint Croix, WI (0.2) / US (2.4)

    Meningitis: Oglala Lakota County, SD (1.2) / Marin County, CA (0.2) / US (0.4)

    Hepatitis: Union County, FL (5.2) / Steel County, ND, and Waukesha County WI (both 0.1) / US (0.3)

    Tuberculosis: Oglala Lakota County, SD (3.5) / Rich County, UT, and Hinsdale County, CO (both 0.1) / US (0.3)

-end-
Media contacts:

IHME


Kelly Bienhoff, +1-206-897-2884 (office); +1-913-302-3817 (mobile); kbien@uw.edu

Dean R. Owen, +1-206-897-2858 (office); +1-206-434-5630 (mobile); dean1227@uw.eduJAMA

JAMA Network Media Relations, +1-312-464-JAMA (5262); mediarelations@jamanetwork.org

About the Institute for Health Metrics and Evaluation

The Institute for Health Metrics and Evaluation (IHME) is an independent global health research organization at the University of Washington that provides rigorous and comparable measurement of the world's most important health problems and evaluates the strategies used to address them. IHME makes this information widely available so that policymakers have the evidence they need to make informed decisions about how to allocate resources to improve population health.

Institute for Health Metrics and Evaluation

Related Tuberculosis Articles:

Blocking the iron transport could stop tuberculosis
The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply.
Tuberculosis: New insights into the pathogen
Researchers at the University of Würzburg and the Spanish Cancer Research Centre have gained new insights into the pathogen that causes tuberculosis.
Unmasking the hidden burden of tuberculosis in Mozambique
The real burden of tuberculosis is probably higher than estimated, according to a study on samples from autopsies performed in a Mozambican hospital.
HIV/tuberculosis co-infection: Tunneling towards better diagnosis
1.2 million people in the world are co-infected by the bacteria which causes tuberculosis and AIDS.
Reducing the burden of tuberculosis treatment
A research team led by MIT has developed a device that can lodge in the stomach and deliver antibiotics to treat tuberculosis, which they hope will make it easier to cure more patients and reduce health care costs.
Tuberculosis: Commandeering a bacterial 'suicide' mechanism
The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein.
A copper bullet for tuberculosis
Tuberculosis is a sneaky disease, and the number one cause of death from infectious disease worldwide.
How damaging immune cells develop during tuberculosis
Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues.
How many people die from tuberculosis every year?
The estimates for global tuberculosis deaths by the World Health Organisation (WHO) and the Institute for Health Metrics and Evaluation (IHME) differ considerably for a dozen countries, according to a study led by ISGlobal.
Beyond killing tuberculosis
Historically, our view of host defense against infection was that we must eliminate pathogens to eradicate disease.
More Tuberculosis News and Tuberculosis Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Making Amends
What makes a true apology? What does it mean to make amends for past mistakes? This hour, TED speakers explore how repairing the wrongs of the past is the first step toward healing for the future. Guests include historian and preservationist Brent Leggs, law professor Martha Minow, librarian Dawn Wacek, and playwright V (formerly Eve Ensler).
Now Playing: Science for the People

#566 Is Your Gut Leaking?
This week we're busting the human gut wide open with Dr. Alessio Fasano from the Center for Celiac Research and Treatment at Massachusetts General Hospital. Join host Anika Hazra for our discussion separating fact from fiction on the controversial topic of leaky gut syndrome. We cover everything from what causes a leaky gut to interpreting the results of a gut microbiome test! Related links: Center for Celiac Research and Treatment website and their YouTube channel
Now Playing: Radiolab

The Flag and the Fury
How do you actually make change in the world? For 126 years, Mississippi has had the Confederate battle flag on their state flag, and they were the last state in the nation where that emblem remained "officially" flying.  A few days ago, that flag came down. A few days before that, it coming down would have seemed impossible. We dive into the story behind this de-flagging: a journey involving a clash of histories, designs, families, and even cheerleading. This show is a collaboration with OSM Audio. Kiese Laymon's memoir Heavy is here. And the Hospitality Flag webpage is here.