Experts define global criteria for hospital programs to tackle antimicrobial resistance

April 02, 2018

Basel, Switzerland, 03 April 2018 - Infection specialists at hospitals are introducing so-called antimicrobial stewardship (AMS) programmes to use antimicrobial drug therapies more responsibly. Such programmes include a coherent set of actions which promote using antimicrobials in ways that ensure sustainable access to effective therapy for all who need them. A group of international experts, led by researchers from the Center for Disease Dynamics, Economics & Policy (CDDEP) in India and the Université de Lorraine in France, has now for the first time defined a standardized set of actions that are relevant for all hospitals around the world to preserve the effectiveness of antimicrobials and limit the emergence of antimicrobial resistance.

The group of international experts selected seven core elements and 29 related checklist items that describe the essential and minimum standards for hospital-based AMS programmes applicable in both high and low-to-middle income countries. The core elements include senior hospital management leadership towards antimicrobial stewardship, accountability and responsibilities, available expertise on infection management, education and practical training. They also include other actions aiming at responsible antimicrobial use, monitoring and surveillance as well as reporting and feedback on a continuous basis.

The current absence of a universal definition for AMS impedes the implementation of such AMS programmes globally, especially in low- and middle-income countries, explains Prof. Céline Pulcini, a professor of infectious diseases in Nancy University Hospital and University of Lorraine, France, who is also secretary of the European Society of Clinical Microbiology and Infectious Diseases' (ESCMID) Study Group for Antimicrobial Stewardship (ESGAP).

"We hope this work will be useful to those who develop national stewardship guidelines in their respective countries," Prof. Pulcini said, adding "that such core elements can also help effectively monitor the implementation of antimicrobial stewardship programmes in hospitals. This is a consensus that is applicable around the world and not just in high-income countries. Antimicrobial resistance is a global problem that needs global solutions, for the benefit of the patients and the greater good. All hospitals should be able to implement a set of essential AMS strategies."

While the resulting list resembles that of the Centers of Diseases Control and Prevention (CDC) of the United States in some points, this new consensus document is more comprehensive and more generic, and is relevant to hospital settings in low and middle-income countries. In addition, the list can be further modified and used for certification, benchmarking, or performance purposes.

The expert panel involved in this work consisted of an international group of 15 specialists from 13 countries on six continents. They include researchers from Argentina, Australia, Belgium, Brazil, China, India, Kenya, Netherlands, South Africa, Switzerland, Thailand, United Kingdom, and the United States, all with hands-on experience of AMS in low and middle-income countries.
-end-
Further information:

Céline Pulcini
University of Lorraine; Nancy University Hospital
Service de Maladies Infectieuses
celine.pulcini@univ-lorraine.fr
Telephone: +33 3 83 15 40 97

Reference:

Céline Pulcini et al., Consensus paper: Developing core elements and checklist items for global hospital antimicrobial stewardship programmes: a consensus approach, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2018.03.033

About ESCMID

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) is a non-profit organisation dedicated to improving the diagnosis, treatment and prevention of infectious diseases. The society promotes and supports research, education, training and good medical practice in infection-related disciplines with a special focus on antimicrobial resistance to build capacity throughout the world. ESGAP is one of ESCMID's study groups working on antimicrobial stewardship. http://www.escmid.org

European Society of Clinical Microbiology and Infectious Diseases

Related Antimicrobial Resistance Articles from Brightsurf:

Treating COVID-19 could lead to increased antimicrobial resistance
Research led by the University of Plymouth suggests the increased use of antibiotics in the treatment of COVID-19 patients could be placing an additional burden on waste water treatment works, particularly those serving large or emergency hospitals

To prevent antimicrobial resistance, vaccinate the world's kids
Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis led by researchers University of California, Berkeley.

Aquaculture at the crossroads of global warming and antimicrobial resistance
Antimicrobial resistance is responsible for some 700 000 deaths each year worldwide.

NHS could save £89 million and further fight against antimicrobial resistance
The NHS could save up to £89 million a year on unnecessary prescriptions for antibiotics, and further its efforts in the fight against antimicrobial resistance -- if it was to comprehensively introduce already available and accurate point-of-care (POCTs) diagnostic tests.

Who will lead the global surveillance of antimicrobial resistance via sewage?
In the journal Science, a DTU professor calls for someone to carry on a global surveillance of antimicrobial resistance and infectious diseases via sewage.

Sequencing sewage for antimicrobial resistance surveillance
In this Policy Forum, Frank Aarestrup and Mark Woolhouse advocate for the immediate establishment of a global antimicrobial resistance surveillance system based on the metagenomic sequencing of human sewage.

Novel composite antimicrobial film could take a bite out of foodborne illnesses
A novel composite film -- created by the bonding of an antimicrobial layer to conventional, clear polyethylene plastic typically used to vacuum-package foods such as meat and fish -- could help to decrease foodborne illness outbreaks, according to researchers in Penn State's College of Agricultural Sciences.

Squid pigments have antimicrobial properties
Ommochromes, the pigments that color the skin of squids and other invertebrates, could be used in the food and health sectors for their antioxidant and antimicrobial properties.

Antimicrobial resistance poses significant risk to people, the economy
CCA expert panel study provides new data on potential impact of antimicrobial resistance in Canada.

Antimicrobial resistance is drastically rising
An international team of researchers led by ETH has shown that antimicrobial-resistant infections are rapidly increasing in animals in low and middle income countries.

Read More: Antimicrobial Resistance News and Antimicrobial Resistance Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.