Nav: Home

Could targeting oxtyocin help treat opioid addiction?

April 05, 2017

A new review of published research indicates that the oxytocin system -- a key player in social reward and stress regulation--is profoundly affected by opioid use. Therefore, it may be an important target for developing medications to treat opioid addiction and to prevent relapse.

"Social withdrawal is one of the key factors that can predispose people to heroin addiction but is also a consequence of drug use," said Dr. Alexis Bailey, senior author of the British Journal of Pharmacology review. "Given the benefits that social support programs like Alcoholics Anonymous and Narcotics Anonymous have in keeping addicts abstinent, current findings in the review suggest the use of the prosocial hormone oxytocin as a novel effective 'psycho-biological therapy' for the prevention of relapse to drug-use in drug dependent individuals. Therefore clinical studies assessing the efficacy of oxytocin-based pharmacotherapies in opioid addiction are warranted."
-end-


Wiley

Related Opioid Articles:

Length of time in US associated with immigrants' opioid use
The more time first-generation immigrants spend in the United States the more likely it appears they will use prescription opioids.
Opioid use disorder in pregnancy: 5 things to know
Opioid use is increasing in pregnancy as well as the general population.
Opioid treatment for teens? Medications can help
Teens who misuse prescription or illicit opioids might benefit from opioid treatment medications, according to a new study led by a Yale researcher.
The 'inflammation' of opioid use
New research correlates inflammation in the brain and gut to negative emotional state during opioid withdrawal.
What we don't know about prenatal opioid exposure
'Will the baby be OK?' In cases of prenatal opioid exposure, the answer is unclear.
Does opioid maintenance treatment during pregnancy harm newborns?
A new Pharmacology Research & Perspectives study found no harm to newborns from opioid maintenance treatment (OMT) during pregnancy compared with no treatment.
Opioid prescribing patterns in children after tonsillectomy
National private insurance claims data were used to examine opioid prescribing patterns in children after tonsillectomy and return visits for complications.
Marijuana legalization reduces opioid deaths
A new Economic Inquiry study finds that marijuana access leads to reductions in opioid-related deaths.
New data indicate rise in opioid use for migraine treatment
An increasing number of Americans are using opioids to treat their migraine headaches, despite the fact that opioids are not the recommended first-line therapy for migraine in most cases.
Opioid use after vaginal or cesarean delivery among US women
This study used national insurance claims data for about 988,000 women to look at the association between an opioid prescription after a vaginal or cesarean delivery and rates of new persistent opioid use among US women.
More Opioid News and Opioid Current Events

Top Science Podcasts

We have hand picked the top science podcasts of 2019.
Now Playing: TED Radio Hour

Risk
Why do we revere risk-takers, even when their actions terrify us? Why are some better at taking risks than others? This hour, TED speakers explore the alluring, dangerous, and calculated sides of risk. Guests include professional rock climber Alex Honnold, economist Mariana Mazzucato, psychology researcher Kashfia Rahman, structural engineer and bridge designer Ian Firth, and risk intelligence expert Dylan Evans.
Now Playing: Science for the People

#540 Specialize? Or Generalize?
Ever been called a "jack of all trades, master of none"? The world loves to elevate specialists, people who drill deep into a single topic. Those people are great. But there's a place for generalists too, argues David Epstein. Jacks of all trades are often more successful than specialists. And he's got science to back it up. We talk with Epstein about his latest book, "Range: Why Generalists Triumph in a Specialized World".
Now Playing: Radiolab

Dolly Parton's America: Neon Moss
Today on Radiolab, we're bringing you the fourth episode of Jad's special series, Dolly Parton's America. In this episode, Jad goes back up the mountain to visit Dolly's actual Tennessee mountain home, where she tells stories about her first trips out of the holler. Back on the mountaintop, standing under the rain by the Little Pigeon River, the trip triggers memories of Jad's first visit to his father's childhood home, and opens the gateway to dizzying stories of music and migration. Support Radiolab today at Radiolab.org/donate.