Lab tests of blu e-vapor show no evidence of damage to human lung cells

April 09, 2019

New peer reviewed research commissioned by Imperial Brands, and conducted by the contract research organisation MatTek, shows vaping blu produces a similar effect on human lung tissue as normal air.

The study, published this month, was conducted to investigate the potential adverse effects of blu vapour on human airway tissue, compared with conventional cigarette smoke.

For the study, researchers used a 3D model of lung tissue in parallel with a VITROCELL smoking/vaping robot to assess the potential toxicity of e-cigarette vapour to human cells.

Two blu nicotine-containing vape products (blu PLUS+ e-cigarette) were tested - with and without flavourings - on real human airway tissue, alongside a conventional 3R4F reference cigarette.

The results were in marked contrast:

Lukasz Czekala, In-Vitro Research Toxicologist at Imperial Brands and study author, commented: "Until now, there have been few in-vitro studies around the potential adverse effects of vapour. This organotypic study sought to closely mimic the exposure of both flavoured and unflavoured vapour and smoke on normal human lung tissue.

"The results we observed build our belief that blu offers compelling potential as a less harmful alternative to smoking. To date, blu has demonstrated its harm reduction potential in every test we've conducted."

Dr Grant O'Connell, Head of Scientific Affairs at Imperial Brands, added: "Our latest research study further evaluates the harm reduction potential of our vaping products.

"We consider it good scientific practice that any future laboratory studies should replicate human physiology as closely as possible before any clinical trials commence, rather than relying on non-realistic human exposures and extrapolated results - both of which are regrettably overly frequent in current vaping research."

"This study reinforces Imperial's commitment to investment in new in-vitro tools and assays which eliminate the need for animal testing, as we continue our progress in substantiating the harm reduction potential of our portfolio of next generation products."
-end-


Imperial Brands

Related Cigarette Articles from Brightsurf:

Examining e-cigarette use among current, former smokers
National survey data were used to look at how common electronic cigarette use is among US adults, if they were current or former smokers and used e-cigarettes to help quit smoking.

Study looks at encoding the odor of cigarette smoke
A recent publication in the Journal of Neuroscience by a group of researchers at the University of Kentucky looks at Encoding the Odor of Cigarette Smoke.

Is e-cigarette use associated with relapse among former smokers?
Whether use of electronic cigarettes among former cigarette smokers was associated with an increased risk of smoking relapse was examined with the use of nationally representative survey data.

New device tracks e-cigarette habits to help curtail usage
A new device that attaches to e-cigarettes can unobtrusively monitor inhalations -- yielding important information for research about when and where people vape, how deeply they inhale and how much nicotine they consume.

Native Americans and higher cigarette use: Stereotype goes up in smoke
University of Arizona Health Sciences study finds when whites and Native Americans in comparable income and education levels are compared, whites consume more cigarettes and are more nicotine dependent.

Cigarette smoke damages our mental health, too
The researchers found that students who smoked had rates of clinical depression that were twice to three times higher than did their non-smoking peers.

Novel respiratory cell changes identified from cigarette smoke exposure
Cigarette smoking changes the types of cells that are present in the respiratory track and some biological processes necessary for detoxification of cigarette smoke are restricted to specific types of cells.

New type of e-cigarette vaping injury described in CMAJ
A research case report describing lung injury related to e-cigarette use in a 17-year-old Canadian may be the first documented case of a new form of damage from vaping products.

Popular electronic cigarette may deliver nicotine more effectively than others
When it comes to nicotine delivery, not all electronic cigarettes are created equally, according to Penn State researchers.

E-cigarette flavors decrease perception of harm among youth
As more and more youth use electronic cigarettes, combined with research showing the health consequences of vaping -- including nicotine addiction -- researchers at the University of North Carolina-Chapel Hill found that non-menthol flavors attract youth and adults to use e-cigarettes and that the use of flavored e-cigarettes contributes to multiple pathways linked to higher e-cigarette use among youth.

Read More: Cigarette News and Cigarette Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.