Heart Laser Surgery: An Alternative To Transplantation

April 17, 1998

HEART LASER SURGERY: AN ALTERNATIVE TO TRANSPLANTATION Researchers at Temple University Hospital are indicating that the use of heart laser surgery may replace transplantation in certain patients with severe coronary artery disease. Clinical results were reported today at the International Society For Heart and Lung Transplantation Meeting in Chicago, Illinois.

According to Valluvan Jeevanandam, M.D., Surgical Director of the Heart Transplantation Program at Temple University Hospital, "this promising new therapy offers an alternative for patients with severe chest pain who may need a heart transplant." This therapy, termed Transmyocardial Revascularization (TMR), uses a carbon dioxide laser to create upwards of 50 tiny holes in the left ventricle of the heart, which improves blood flow to oxygen-starved heart muscle

. TMR was developed to relieve debilitating chest pain, called angina, in patients who are not candidates for angioplasty or bypass surgery. After six months of follow-up, patients receiving TMR in this study showed a dramatic improvement in the amount of chest pain and quality of life. "We were able to preserve hear function while improving health status without the need for heart transplantation in TMR patients," says Dr. Jeevanandam.

Approximately 250,000 people suffer from end-stage coronary artery disease and that number is growing by an estimated 20% each year. Many of these individuals can not have bypass surgery and are potential heart transplant candidates.

According to Dr. Jeevanandam, "Due to the lack of sufficient numbers of donor hearts, TMR offers a cost-effective alternative to heart transplantation without the side effects of immunosuppression therapy."

Based upon scientific registry data from the United Network for Organ Sharing (UNOS), there are currently about 3,945 patients waiting for a heart transplant.

Using 1996 data, it is estimated that about 20 to 50% of these patients may die while waiting for a donor heart. Dr. Jeevanandam says, "Our survival rate was 85% which compares favorably with survival at 1 year post transplant. We don't know yet if TMR will help these patients live longer, but TMR patients are spared the mortality associated with waiting for a transplant."
-end-


Temple University Health System

Related Heart Transplant Articles from Brightsurf:

Does the new heart transplant allocation policy encourage gaming by providers?
A new national policy was created to make determining who receives a heart transplant more fair.

Tiny biological package gets drug right to the 'heart' of transplant rejection
For patients who receive a heart transplant in the near future, the old adage, 'Good things come in small packages,' may become words to live by.

Survival on heart transplant waiting list
Survival of patients on the heart transplant waiting list was examined in this observational study.

Double surgery improves chances for heart transplant in patients with obesity
Pairing bariatric surgery with LVAD heart surgery may be an effective bridge to heart transplant for obese patients.

Changes in US heart transplant waitlist activity, volume during COVID-19 pandemic
National and regional changes in waitlist inactivations and additions, donor recovery and heart transplant volume during the COVID-19 pandemic are described in this observational study.

Racial, gender disparities observed in heart transplant recipients with COVID-19 infection
Researchers suggest focusing on disparities to help identify which patients with a heart transplant may be at higher risk for a worse course of COVID-19 infection.

Characteristics, outcomes of heart transplant recipients with COVID-19
The characteristics, treatment and outcomes of heart transplant recipients who were infected with COVID-19 in New York City are described in this case series.

PET imaging offers new insights into post-transplant care for heart patients
Myocardial blood flow (MBF) and myocardial flow reserve (MFR) have been identified as accurate indicators for graft failure after cardiac transplantation, according to research published in The Journal of Nuclear Medicine.

Massachusetts General Hospital performs first-of-its-kind heart transplant in New England
Mass General Hospital recently performed the largest number of adult heart transplants in the country using what are known as Donation after Circulatory Death (DCD) donor hearts.

Air pollution may increase mortality risk after heart transplant
Heart transplant recipients who live in areas where particulate matter (PM2.5) air pollution levels reached above national limits for clean air had a 26% higher risk of mortality due to infection, according to a study published today in the Journal of the American College of Cardiology.

Read More: Heart Transplant News and Heart Transplant Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.