Effect of 18F-FDG PET/CT in esophageal cancer patients with early recurrence lesions

April 18, 2009

In the initial staging of esophageal cancer, preoperative PET scan may be useful in detecting additional cases of metastatic disease before costly and toxic definitive therapy. Currently, 18F-FDG PET and PET/CT also seem to be the best available tools for neoadjuvant therapy response assessment in esophageal cancer. However, the utility and limitation of 18F-FDG PET/CT in patients with esophageal cancer treated by surgical resection and post operation radiation is not clear.

A research article to be published on April 21, 2009 in the World Journal of Gastroenterology addresses this question. The research carried out by Professor Wu from Minnan PET Center and department of nuclear medicine aimed to evaluate the clinical usefulness of 18F-FDG PET/CT in the restaging of esophageal cancer after surgical resection and radiotherapy. Their initial results suggested 18F-FDG PET/CT is might be a highly sensitive diagnosis and accurate whole-body staging of asymptomatic and symptomatic recurrent esophageal cancer. 18F-FDG PET/CT guided- salvage treatment to the early recurrence lesion might improve patient survival in a considerable proportion of patients.
Reference: Sun L, Su XH, Guan YS, Pan WM, Luo ZM, Wei JH, Zhao L,Wu H. Clinical usefulness of 18F-FDG PET/CT in the restaging of esophageal cancer after surgical resection and radiotherapy.World J Gastroenterol 2009; 15(15): 1836-1842


Correspondence to: Hua Wu, Minnan PET Center and Department of Nuclear Medicine, the First Hospital of Xiamen, Fujian Medical University, Xiamen 316003, Fujian Province, China. wuhua1025@163.com

Telephone: +86-592-2139527 Fax: +86-592-2139527

World Journal of Gastroenterology

Related Esophageal Cancer Articles from Brightsurf:

Pathological regression of lymph nodes better predicts esophageal cancer survival
A team of researchers led by Osaka University established a new pathological grading system to evaluate the therapeutic effect of neoadjuvant chemotherapy (NAC) for metastatic lymph nodes (LNs) removed in esophageal cancer (EC) surgery, demonstrating that the system predicts recurrence and prognosis in EC patients better than conventional systems.

Racial disparities in surgery rates for esophageal cancer
Black patients with esophageal cancer are less likely to receive life-saving surgery for early-stage disease than white patients.

Portable 'electronic nose' can accurately pick up esophageal cancer precursor
A portable 'electronic nose' can accurately pick up the precursor condition to food pipe (esophageal) cancer, known as Barrett's esophagus, indicates a proof of principle study, published online in the journal Gut.

A new machine learning approach detects esophageal cancer better than current methods
Dartmouth scientists have proposed a new machine learning model for identification of esophageal cancer that could open new avenues for applying deep learning to digital pathology.

Lymph nodes can predict survival in patients with esophageal cancer
It is difficult for physicians to estimate recurrence and survival in patients with esophageal cancer.

New model improves staging and risk predictions for esophageal cancer patients
A new nomogram for assessing metastatic risk in esophageal cancer patients shows promise for more accurate risk-stratification, which is particularly relevant for stage T2 patients.

Combo of virotherapy and radiotherapy shows early promise in patients with esophageal cancer
The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3.

Drinking hot tea linked with elevated risk of esophageal cancer
Previous studies have revealed a link between hot tea drinking and risk of esophageal cancer, but until now, no study has examined this association using prospectively and objectively measured tea drinking temperature.

Test for esophageal cancer could save millions of lives
Cancer of the esophagus claims more than 400,000 lives around the world each year.

Genome offers clues to esophageal cancer disparity
A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

Read More: Esophageal Cancer News and Esophageal Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.