Award lectures for ASBMB's 2007 Annual Meeting

April 23, 2007

BETHESDA - The 2007 annual meeting of the American Society for Biochemistry and Molecular Biology (ASBMB) will feature the latest news about cell biology, signaling pathways, and genome dynamics, with 156 presentations in over 50 sessions. The meeting will also include award lectures and sessions on educational and professional development, minority affairs studies, and the interplay between the biomedical sciences and public policy. The meeting will take place at the Washington Convention Center, 801 Mt. Vernon Place, NW, Washington, D.C., from April 28 to May 2.

The ASBMB meeting is part of a multi-society meeting called Experimental Biology 2007 (EB 2007), which also includes the annual meetings of the American Association of Anatomists, the American Physiological Society, the American Society for Investigative Pathology, the American Society for Nutrition, and the American Society for Pharmacology and Experimental Therapeutics.

Members of the media need to register during the meeting at the EB 2007 Press Room, located in the Convention Center East Registration Level 1.

Brief descriptions of the Award Lectures follow. The times indicated below may vary depending on the time taken by preceding presentations.


ASBMB Opening Lecture and Herbert Tabor/Journal of Biological Chemistry Lectureship - 6:05 p.m.-6:50 p.m., Ballroom C

"Tyrosine Phosphorylation: From Discovery to the Kinome and Beyond"
TONY HUNTER, American Cancer Society Professor of Molecular and Cell Biology at the Salk Institute for Biological Studies, La Jolla, Calif., will discuss the latest results on studies of the human kinome - a catalogue of genes that express key cellular proteins called protein kinases. Mutations in these genes have been found to cause various diseases, including cancer, which explains the current high interest in this topic.

ASBMB Opening Lecture and Herbert Tabor/Journal of Biological Chemistry Lectureship - 6:50 p.m.-7:30 p.m., Ballroom C
"Phosphotyrosine Signaling: A Prototype for Modular Protein-Protein Interactions"
TONY PAWSON, Senior Investigator at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital in Toronto, Canada, will discuss how proteins "talk" to each other. He will argue that such protein interactions allow biological functions to evolve and that when these interactions go awry, they can cause diseases.


Avanti Award in Lipids - 8:30 a.m.-9:30 a.m., Ballroom C

"Phosphoinositide Lipid Signaling in the Regulation of Membrane Trafficking and Organelle Identity"
SCOTT D. EMR, Investigator with the Howard Hughes Medical Institute and Professor of Cellular and Molecular Medicine in the School of Medicine at the University of California, San Diego, will present recent research on phosphoinositide lipids, which are molecules in cell membranes that regulate cell growth; the transport of molecules between or within cells; and the arrangement of the cell's cytoskeleton, a network of fibers throughout the cell's cytoplasm that helps the cell maintain its shape and gives it support.

ASBMB Award for Exemplary Contributions to Education - 12:30 p.m.-1:30 p.m., Room 201
"The Importance of Research in the Undergraduate Curriculum: Explorations in Genomics"
SARAH C. ELGIN, Professor of Biology, Genetics and Education at Washington University, St. Louis, Mo., will explain how students and scientists are working together on a research project that annotates and analyzes fruit fly chromosomes. Future projects will take advantage of the increasing amount of data on genomes, large and small, now available in public databases.

ASBMB-Merck Award - 2:15 p.m.-3:15 p.m., Ballroom C
"Quinoproteins and Cofactors: Expecting the Unexpected"
JUDITH P. KLINMAN, Professor of Chemistry at the University of California, Berkeley, will describe a new family of proteins called quino-enzymes. Most enzymes can interact with each other through small molecules called coenzymes that attach to the enzymes' surfaces, but quino-enzymes display coenzymes inside their structure. Klinman will describe some of the unexpected features of these quino-enzymes.


Fritz Lipmann Lectureship - 8:30 a.m.-9:30 a.m., Ballroom C

"PPARs: Running Around Obesity"
RONALD M. EVANS, Professor of Biology at the Salk Institute for Biological Studies, San Diego, Calif. will present the latest findings on the potential anti-obesity effects of a receptor located on cell nuclei called peroxisome proliferator-activated receptor delta (PPAR-delta). The receptor is already known to regulate inflammation, suggesting it may be an effective drug against heart disease. Evans and his team have shown that PPAR-delta helps the liver resume its normal function in obese mice. Evans will discuss how PPAR-delta activation in muscle can dramatically enhance running endurance, producing a strain of marathon mice.


Schering-Plough Research Institute Award - 8:30 a.m.-9:30 a.m., Ballroom C

"Towards an RNA Splicing Code"
CHRISTOPHER B. BURGE, Associate Professor of Biology at MIT, will discuss the latest results on how a messenger RNA is modified - by removing its non-coding portions - before being used to produce proteins. He will present some of the key players (proteins and RNA) that induce these changes and how they interact with each other.

Howard K. Schachman Public Service Award - 12:30 p.m.-1:30 p.m., Room 201
"Public Policy and Biomedical Research"
MARY WOOLLEY, President and CEO of Research!America, the nation's largest not-for-profit public education and advocacy alliance, will comment on the current public and political climate for medical research and discuss why and how researchers can become more involved in making research a much higher national priority.

ASBMB - Amgen Award - 2:15 p.m.-3:15 p.m., Ballroom C
"Causes and Consequences of Aneuploidy"
ANGELIKA AMON, Associate Professor of Biology at MIT, will present the latest research on what can go wrong during cell division and the consequences thereof. When cell division goes wrong, cells can either become cancerous or end up with an abnormal number of chromosomes - a condition called aneuploidy and involved in causing cancer. Amon will describe her work on how cells become aneuploid and how her findings may provide new hints into the genetic origins of cancer.


William C. Rose Award - 8:30 a.m.-9:30 a.m., Ballroom C

"Dynamics of Signaling by Protein Kinase A"
SUSAN S. TAYLOR, Professor of Chemistry and Biochemistry at the University of California, San Diego, will describe new findings on the structure of protein kinase A, a key enzyme that has several functions in mammalian cell, including regulation of glucose and lipid metabolism. She will explain the dynamic changes that are necessary to allow protein kinase A to become active. These changes have relevance for all members of the protein kinase superfamily.

American Society for Biochemistry and Molecular Biology

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