Japanese women found to have lower recurrence of breast cancer

May 01, 2005

May 2, 2005 - Early-stage breast cancer patients of Japanese descent that are treated with a lumpectomy and radiation therapy are more likely to be cured of their cancer than women of other ancestries, according to a new study published in the May 2005 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.

The study, conducted on 896 patients treated at Kuakini Medical Center in Honolulu from 1990 to 2001, found that only six women (.67 percent) experienced a local recurrence of their breast cancer in the first six years after treatment. The patients in the study all had Tis, T1 or T2 tumors, considered early stage, with no spread to other organs or distant sites in the body. Seventy-four percent of the patients in this study were of Japanese heritage.

This figure is remarkable considering the local recurrence rates for women of all ethnicities with breast cancer published from academic centers all over the world range from two to 16 percent. Overall, the Kuakini Medical Center's survival data were superior to the National Cancer Data Base.

"This low rate of local relapse is extraordinary and unmatched by the published data results generally cited in the literature," said Mark Kanemori, M.D., lead author of the study and a radiation oncologist at Kuakini Medical Center. "This study suggests that there are biological factors that may be related to ethnicity. Hopefully, this will spark interest in the academic community to further research in this area. Identifying predictive factors of cancer biology may lead to improvements in our ability to properly select appropriate cancer treatments for our patients."
-end-
For more information on radiation therapy for breast cancer cancer, please visit www.astro.org/patient/treatment_information/ for a free brochure.

To arrange an interview with Dr. Kanemori or for a copy of the study "Results of Breast Conservation Therapy From a Single-Institution Community Hospital in Hawaii With a Predominantly Japanese Population," please contact Nick Lashinsky at nickl@astro.org or 1-800-962-7876.

ASTRO is the largest radiation oncology society in the world, with more than 8,000 members who specialize in treating patients with radiation therapies. As a leading organization in radiation oncology, biology and physics, the Society is dedicated to the advancement of the practice of radiation oncology by promoting excellence in patient care, providing opportunities for educational and professional development, promoting research and disseminating research results and representing radiation oncology in a rapidly evolving socioeconomic healthcare environment.

American Society for Radiation Oncology

Related Breast Cancer Articles from Brightsurf:

Oncotarget: IGF2 expression in breast cancer tumors and in breast cancer cells
The Oncotarget authors propose that methylation of DVDMR represents a novel epigenetic biomarker that determines the levels of IGF2 protein expression in breast cancer.

Breast cancer: AI predicts which pre-malignant breast lesions will progress to advanced cancer
New research at Case Western Reserve University in Cleveland, Ohio, could help better determine which patients diagnosed with the pre-malignant breast cancer commonly as stage 0 are likely to progress to invasive breast cancer and therefore might benefit from additional therapy over and above surgery alone.

Partial breast irradiation effective treatment option for low-risk breast cancer
Partial breast irradiation produces similar long-term survival rates and risk for recurrence compared with whole breast irradiation for many women with low-risk, early stage breast cancer, according to new clinical data from a national clinical trial involving researchers from The Ohio State University Comprehensive Cancer Center - Arthur G.

Breast screening linked to 60 per cent lower risk of breast cancer death in first 10 years
Women who take part in breast screening have a significantly greater benefit from treatments than those who are not screened, according to a study of more than 50,000 women.

More clues revealed in link between normal breast changes and invasive breast cancer
A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.

Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells
A highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report in Nature Communications that they have identified a novel pathway for connective tissue PTEN in breast cancer cell response to radiotherapy.

Computers equal radiologists in assessing breast density and associated breast cancer risk
Automated breast-density evaluation was just as accurate in predicting women's risk of breast cancer, found and not found by mammography, as subjective evaluation done by radiologists, in a study led by researchers at UC San Francisco and Mayo Clinic.

Blood test can effectively rule out breast cancer, regardless of breast density
A new study published in PLOS ONE demonstrates that Videssa® Breast, a multi-protein biomarker blood test for breast cancer, is unaffected by breast density and can reliably rule out breast cancer in women with both dense and non-dense breast tissue.

Study shows influence of surgeons on likelihood of removal of healthy breast after breast cancer dia
Attending surgeons can have a strong influence on whether a patient undergoes contralateral prophylactic mastectomy after a diagnosis of breast cancer, according to a study published by JAMA Surgery.

Young breast cancer patients undergoing breast conserving surgery see improved prognosis
A new analysis indicates that breast cancer prognoses have improved over time in young women treated with breast conserving surgery.

Read More: Breast Cancer News and Breast Cancer Current Events
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.