Characterizing two sisters, examples of exceptional longevity

May 01, 2020

New Rochelle, NY, May 1, 2020--A new study provides a detailed characterization of two sisters - one a supercentenarian and one a semi-supercentenarian--aimed at providing new insights into what allowed them to live such long lives. The authors conclude that supercentenarians have a relatively increased resistance to age-related diseases and can approach the limits of the functional human reserve to avoid the acute causes of death. The article is published in Rejuvenation Research, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Click Rejuvenation Research website through June 1, 2020.

The article is entitled

The sisters never smoked and slept 5-6 hours per night. They did not show a close adherence to the Mediterranean Diet. Based on the phenotypic and genotypic characterization, the researchers believe that inflammation and oxidative stress predict centenarian mortality.

"The study of those who attain exceptional longevity is among the most impactful areas of biomedical gerontology, especially because it generally arises from staying healthy until an exceptional age. This unique case of two sisters reaching such extreme ages offers a remarkable chance to unearth secrets to maintaining health, and Dr. Caruso's team have done the field a great service with this study," says Editor-in-Chief Aubrey D.N.J. de Grey, SENS Research Foundation, Mountain View, CA.
About the Journal

Aubrey D.N.J. de Grey, PhD, SENS Foundation, Mountain View, CA, the Journal provides key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence. Rejuvenation Research is the Official Journal of the European Society of Preventive, Regenerative and Anti-Aging Medicine (ESAAM) and the World Federation & World Virtual Institute of Preventive & Regenerative Medicine (PYRAMED). Complete tables of content and a sample issue may be viewed on the website.

About the Publisher

Mary Ann Liebert, Inc./Genetic Engineering News

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