MRI is better than PET for detecting small metastatic lesions in the liver

May 06, 2004

Contrast enhanced MRI should be the imaging method of choice for determining if patients with gastrointestinal cancer have disease that has spread into their liver, a new study shows.

The study compared FDG PET to MRI and found that both diagnosed cancer metastases, however, MRI was better able to detect more and smaller lesions in the patients, said Dushyant Sahani, MD, one of the authors of the study.

The study included 30 patients with 97 metastatic lesions. MRI detected 79 of the lesions, 33 of which were less than 1 cm. PET detected 65 of the 97 lesions, 12 of which measured less than 1 cm. The number of lesions and the size of lesions are critical, said Dr. Sahani, because that is what determines treatment. "Per lesion analysis showed that MRI had an accuracy rate of 75.5% compared to 64.1% for PET," said Dr. Sahani.

Dr. Sahani noted that the MRI contrast agent that was used in the study was specifically designed for imaging the liver. The contrast agent stayed in the liver for a couple of hours, allowing the radiologist to obtain a higher resolution image and thinner image slices, he said. The contrast agent that was used in the study is not currently available, however, there are other liver-specific agents, which are awaiting approval from the Food and Drug Administration, Dr. Sahani said.

The study will be presented on May 6 at the American Roentgen Ray Society Annual Meeting in Miami Beach, FL.
Jason Ocker 703-858-4304
Press Room 786-276-1351

American College of Radiology

Related MRI Articles from Brightsurf:

Does MRI have an environmental impact?
Researchers from Tokyo Metropolitan University have surveyed the amount of gadolinium found in river water in Tokyo.

MRI predict intelligence levels in children?
A group of researchers from the Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) took 4th place in the international MRI-based adolescent intelligence prediction competition.

7T MRI offers new insights into multiple sclerosis
Investigators from Brigham and Women's Hospital have completed a new study using 7 Tesla (7T) MRI -- a far more powerful imaging technology -- to further examine LME in MS patients

Magnetic eyelashes: A new source of MRI artifacts
American Journal of Roentgenology researchers used a phantom to show that magnetic eyelashes worn during MRI can cause substantial artifact and that detachment of the eyelashes from the phantom can occur.

High-strength MRI tracks MS progression
The development of scars, or lesions, in the brain's cortical gray matter is a powerful predictor of neurological disability for people with multiple sclerosis (MS), according to new study.

Non-contrast MRI is effective in monitoring MS patients
Brain MRI without contrast agent is just as effective as the contrast-enhanced approach for monitoring disease progression in patients with multiple sclerosis (MS), according to a new study.

Researchers use MRI to predict Alzheimer's disease
MRI brain scans perform better than common clinical tests at predicting which people will go on to develop Alzheimer's disease, according to a new study.

Monitoring electromagnetic signals in the brain with MRI
MIT engineers have devised a new technique to detect either electrical activity or optical signals in the brain, using a minimally invasive technique based on magnetic resonance imaging (MRI).

MRI 'glove' provides new look at hand anatomy
A new kind of MRI component in the shape of a glove delivers the first clear images of bones, tendons and ligaments moving together.

Why we need erasable MRI scans
Gas-filled protein structures could one day be used as 'erasable' contrast agents for MRI scans.

Read More: MRI News and MRI Current Events is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to