Nav: Home

Management of radial scars diagnosed on core biopsy during transition to tomosynthesis

May 08, 2019

Leesburg, VA, May 8, 2019--It may be safe to follow-up pure radial scars (RSs) diagnosed on core needle biopsy (CNB) instead of surgical excision, according to a study to be presented at the ARRS 2019 Annual Meeting, set for May 5-10 in Honolulu, HI.

The study, to be presented by Dr. Ingolf Karst of Northwestern Medicine in Chicago, was conducted to determine if the greater conspicuity of findings such as architectural distortion on digital breast tomosynthesis (DBT) versus full-field digital mammography (FFDM) would increase the detection and upgrade (UG) rate of RSs, and to identify factors informing the decision to excise surgically or observe.

The retrospective study analyzed screening and diagnostic exams during a 33-month period of transition to DBT (December 2014 to August 2017) to map the frequency of RS found on CNB and their UG rates over time in monthly increments. A 12-month (December 2014 to November 2015) pretransition timeframe (TF) was compared with a 12-month TF after transition (September 2016 to August 2017) for RSs found, UG rates, and influencing factors. The study reviewed 131,918 exams in total, consisting of 115,430 screening followed by 16,488 diagnostic mammographic exams.

Analysis of the data revealed an 82.5% relative increase in the number of RSs found after transition to DBT, and a relative decrease in UG rate compared to the pretransition TF of 54.4%. There were no upgrades to invasive cancer of all 108 diagnosed radial scars. Seventy-eight of 108 RSs were pure RSs, none of which were upgraded on excision.

UG rates for RSs diagnosed on CNB decreased after transitioning from FFDM to DBT. With no upgrades to invasive cancer or ductal carcinoma in situ (DCIS) found for pure RS, results suggest it may be safe to follow-up pure RS diagnosed on CNB.

"Interdisciplinary collaboration and use of our proprietary database deepened our knowledge of imaging findings and related pathology, such as architectural distortion and radial scar, and supports us in management changes during times of technological shifts, such as transition from FFDM to DBT, to benefit our patients" Dr. Karst stated.
-end-
With educational activities representing the entire spectrum of radiology, ARRS will host leading radiologists from around the world at the ARRS 2019 Annual Meeting, May 5-10, at the Hawaii Convention Center in Honolulu, Hawaii. For more information, visit: http://www.arrs.org/am19.

American Roentgen Ray Society

Related Invasive Cancer Articles:

Study shows link between precipitation, climate zone and invasive cancer rates in the US
In a new study, researchers provide conclusive evidence of a statistical relationship between the incidence rates of invasive cancer in a given area in the US and the amount of precipitation and climate type (which combines the temperature and moisture level in an area).
Blood test can replace invasive biopsy for more patients with lung cancer
A growing number of patients with advanced lung cancer could soon be offered a blood test to help to decide the best treatment for them instead of having to get a tumour sample for analysis.
Semen miRNAs could be non-invasive biomarkers for prostate cancer
Researchers of the Human Molecular Genetics group at the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr.
New blood test for prostate cancer is highly-accurate and avoids invasive biopsies
A new and simple blood test has been found to efficiently and accurately detect the presence of aggressive prostate cancer, according to research by Queen Mary University of London.
Non-invasive imaging method spots cancer at the molecular level
Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or the use of a contrast dye.
Raman spectroscopy poised to make thyroid cancer diagnosis less invasive
Researchers have demonstrated that an optical technique known as Raman spectroscopy can be used to differentiate between benign and cancerous thyroid cells.
Lung cancer: Less invasive surgery for faster recovery
Every day, 78 Canadians receive a diagnosis of lung cancer, the most deadly form of cancer.
Six factors may predict invasive breast cancer recurrence after DCIS diagnosis
Six factors were associated with invasive recurrence of breast cancer after a diagnosis of ductal carcinoma in situ (DCIS), according to data from a meta-analysis.
Researchers develop accurate, non-invasive method to detect bladder cancer
A research team has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder.
A protein that makes skin cancer cells more invasive
Loss of a protein called TRIM29 promotes cancer cell invasion in a common type of skin cancer, suggesting a novel diagnostic marker and a possible therapeutic target.
More Invasive Cancer News and Invasive Cancer Current Events

Top Science Podcasts

We have hand picked the top science podcasts of 2019.
Now Playing: TED Radio Hour

In & Out Of Love
We think of love as a mysterious, unknowable force. Something that happens to us. But what if we could control it? This hour, TED speakers on whether we can decide to fall in — and out of — love. Guests include writer Mandy Len Catron, biological anthropologist Helen Fisher, musician Dessa, One Love CEO Katie Hood, and psychologist Guy Winch.
Now Playing: Science for the People

#543 Give a Nerd a Gift
Yup, you guessed it... it's Science for the People's annual holiday episode that helps you figure out what sciency books and gifts to get that special nerd on your list. Or maybe you're looking to build up your reading list for the holiday break and a geeky Christmas sweater to wear to an upcoming party. Returning are pop-science power-readers John Dupuis and Joanne Manaster to dish on the best science books they read this past year. And Rachelle Saunders and Bethany Brookshire squee in delight over some truly delightful science-themed non-book objects for those whose bookshelves are already full. Since...
Now Playing: Radiolab

An Announcement from Radiolab