Nav: Home

Ontario rotavirus hospitalizations drop >70 percent after launch of infant vaccine program

May 12, 2016

Hospitalization for rotavirus infections decreased by > 70% following the introduction of a vaccine program in Ontario, Canada, according to a study published May 11, 2016 in the open-access journal PLOS ONE by Sarah Wilson from Public Health Ontario and the Institute for Clinical Evaluative Sciences, Canada, and colleagues.

Rotavirus infection may cause acute gastroenteritis, including vomiting, diarrhea, fever, and abdominal pain, and may lead to severe dehydration. Previous research found that for Canadian children infected with rotavirus, one third see a doctor, 15% visit the emergency department, and 7% require hospitalization. The virus is highly infectious and may easily spread to other family members and caregivers of a sick child. In 2011, Ontario became one of the first Canadian provinces to implement a universal, publicly funded rotavirus immunization program for babies at 2 and 4 months of age. With data spanning eight years, the authors of this study analyzed > 860,000 hospitalization and emergency department records for rotavirus infection and acute gastroenteritis, both before and after the introduction of the program.

While data from only one complete rotavirus season was included in the analysis, the authors found that the number of children and adults showing up at Ontario hospitals with acute gastroenteritis dropped considerably after the introduction of the rotavirus vaccine program. Since seasonal oscillations can be observed in rotavirus infection rates, the authors intend to extend their analyses in the future to confirm their findings.

"We were very excited to see the significant impact of the rotavirus vaccine program. Hospitalizations in Ontario due to rotavirus infection were reduced by 71%, and emergency department visits dropped by 68%," says Dr. Sarah Wilson, lead author of the study. "We expected to see a drop for babies and toddlers who were vaccinated under this program. What's particularly interesting is we saw the drop even in older kids who were too old to receive the publicly funded rotavirus vaccine, which means that protecting babies against illness also benefited older children."
-end-
Adapted by PLOS ONE from release provided by the author

In your coverage please use this URL to provide access to the freely available paper: http://dx.plos.org/10.1371/journal.pone.0154340

Citation: Wilson SE, Rosella LC, Wang J, Le Saux N, Crowcroft NS, Harris T, et al. (2016) Population-Level Impact of Ontario's Infant Rotavirus Immunization Program: Evidence of Direct and Indirect Effects. PLoS ONE 11(5): e0154340. doi:10.1371/journal.pone.0154340

Funding: This project was funded by Public Health Ontario (http://www.publichealthontario.ca) and conducted at the Institute for Clinical Evaluative Sciences (ICES), which is funded by an annual grant from the Ontario Ministry of Health and Long-Term Care. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

PLOS

Related Emergency Department Articles:

Patient race & gender are important in predicting heart attack in the emergency department
Researchers at the George Washington University published research finding that certain symptoms are more and less predictive of patients' risk for acute coronary syndrome, which includes heart attack, in patients of different gender and race.
What are trends in emergency department utilization, costs for shingles?
A new article published by JAMA Dermatology uses a nationwide database of emergency department (ED) visits to examine herpes zoster (HZ, shingles)-related ED utilization and costs.
Many cancer patients' Emergency Department visits appear preventable
As many as 53 percent of cancer patients' Emergency Department visits that do not require admission could be avoided with better symptom management and greater availability of outpatient care tailored to their needs, according to a new study from Fred Hutchinson Cancer Research Center.
Lawn mower injuries send 13 children to the emergency department every day
A recent study from the Center for Injury Research and Policy at Nationwide Children's Hospital published in the American Journal of Emergency Medicine shows that, while there has been a decrease in the number of children injured by lawn mowers over the last few decades, this cause of serious injury continues to be a concern.
Cotton tip applicators are sending 34 kids to the emergency department each day
A study conducted by Nationwide Children's Hospital researchers found that over a 21-year period from 1990 through 2010, an estimated 263,000 children younger than 18 years of age were treated in US hospital emergency departments for cotton tip applicator related ear injuries -- that's about 12,500 annually, or about 34 injuries every day.
Regions with stronger gun laws have fewer gun-related pediatric emergency department visits
Regions of the United States with the strictest gun laws also have the fewest emergency department visits for pediatric firearm-related injuries, according to a new study by Children's National Health System researchers.
Intervention reduced suicide attempts among at-risk emergency department patients
Among suicidal patients, an intervention that included brief post-discharge phone calls significantly reduced the likelihood of a future suicide attempt, according to a clinical trial conducted at eight hospitals.
Study examines emergency department visits for patients injured by law enforcement in the US
From 2006 to 2012, there were approximately 51,000 emergency department visits per year for patients injured by law enforcement in the United States, with this number stable over this time period, according to a study published by JAMA Surgery.
Predicting a patient's future firearm violence risk in the emergency department
A new study, from researchers at Michigan Medicine, sought to provide emergency department physicians with a new clinical risk index tool to gauge firearm violence risk among urban youth.
Adolescents with autism four times more likely to visit emergency department
Adolescents with autism spectrum disorder (ASD) use emergency-department services four times as often as their peers without autism, according to Penn State College of Medicine researchers.

Related Emergency Department Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Climate Crisis
There's no greater threat to humanity than climate change. What can we do to stop the worst consequences? This hour, TED speakers explore how we can save our planet and whether we can do it in time. Guests include climate activist Greta Thunberg, chemical engineer Jennifer Wilcox, research scientist Sean Davis, food innovator Bruce Friedrich, and psychologist Per Espen Stoknes.
Now Playing: Science for the People

#527 Honey I CRISPR'd the Kids
This week we're coming to you from Awesome Con in Washington, D.C. There, host Bethany Brookshire led a panel of three amazing guests to talk about the promise and perils of CRISPR, and what happens now that CRISPR babies have (maybe?) been born. Featuring science writer Tina Saey, molecular biologist Anne Simon, and bioethicist Alan Regenberg. A Nobel Prize winner argues banning CRISPR babies won’t work Geneticists push for a 5-year global ban on gene-edited babies A CRISPR spin-off causes unintended typos in DNA News of the first gene-edited babies ignited a firestorm The researcher who created CRISPR twins defends...