Nav: Home

Chewing gums reveal the oldest Scandinavian human DNA

May 15, 2019

The first humans who settled in Scandinavia more than 10,000 years ago left their DNA behind in ancient chewing gums, which are masticated lumps made from birch bark pitch. This is shown in a new study conducted at Stockholm University and published in Communications Biology.

There are few human bones of this age, close to 10 000 years old, in Scandinavia, and not all of them have preserved enough DNA for archaeogenetic studies. In fact, the DNA from these newly examined chewing gums is the oldest human DNA sequenced from this area so far. The DNA derived from three individuals, two females and one male, creates an exciting link between material culture and human genetics.

Ancient chewing gums are as of now an alternative source for human DNA and possibly a good proxy for human bones in archaeogenetic studies. The investigated pieces come from Huseby-Klev, an early Mesolithic hunter-fisher site on the Swedish west coast. The sites excavation was done in the early 1990's, but at this time it was not possible to analyse ancient human DNA at all, let alone from non-human tissue. The masticates were made out of birch bark tar and used as glue in tool production and other types of technology during the Stone Age.

"When Per Persson and Mikael Maininen proposed to look for hunter-gatherer DNA in these chewing gums from Huseby Klev we were hesitant but really impressed that archaeologists took care during the excavations and preserved such fragile material", says Natalija Kashuba, who was affiliated to The Museum of Cultural History in Oslo when she performed the experiments in cooperation with Stockholm University.

"It took some work before the results overwhelmed us, as we understood that we stumbled into this almost 'forensic research', sequencing DNA from these mastic lumps, which were spat out at the site some 10 000 years ago!" says Natalija Kashuba. Today Natalija is a Ph.D. student at Uppsala University.

Exciting link between material culture and human genetics

The results show that, genetically, the individuals whose DNA was found share close genetic affinity to other hunter-gatherers in Sweden and to early Mesolithic populations from Ice Age Europe. However, the tools produced at the site were a part of lithic technology brought to Scandinavia from the East European Plain, modern day Russia. This scenario of a culture and genetic influx into Scandinavia from two routes was proposed in earlier studies, and these ancient chewing gums provides an exciting link directly between the tools and materials used and human genetics.

Emrah Kirdök at Stockholm University conducted the computational analyses of the DNA. "Demography analysis suggests that the genetic composition of Huseby Klev individuals show more similarity to western hunter-gatherer populations than eastern hunter-gatherers", he says.

"DNA from these ancient chewing gums have an enormous potential not only for tracing the origin and movement of peoples long time ago, but also for providing insights in their social relations, diseases and food.", says Per Persson at the Museum of Cultural History in Oslo. "Much of our history is visible in the DNA we carry with us, so we try to look for DNA where ever we believe we can find it", says Anders Götherström, at the Archaeological Research Laboratory at Stockholm University, where the work was conducted. The study is published in Communications Biology.
-end-
DOI: 10.1038/s42003-019-0399-1

Contact information: Natalija Kashuba, lead author of the study and Ph. D. student at Uppsala University: phone: +46702112406, mail: natalija.kashuba@arkeologi.uu.se

Per Persson, archaeologist at the Museum of Cultural History in Oslo: phone +4795170690, mail perap@khm.uio.no

Anders Götherström, Professor in Molecular Archaeology and director of the archaeogenetics at the Archaeological Research Laboratory at Stockholm University: phone +4673 992 78 64, mail

Stockholm University

Related Dna Articles:

A new spin on DNA
For decades, researchers have chased ways to study biological machines.
From face to DNA: New method aims to improve match between DNA sample and face database
Predicting what someone's face looks like based on a DNA sample remains a hard nut to crack for science.
Self-healing DNA nanostructures
DNA assembled into nanostructures such as tubes and origami-inspired shapes could someday find applications ranging from DNA computers to nanomedicine.
DNA design that anyone can do
Researchers at MIT and Arizona State University have designed a computer program that allows users to translate any free-form drawing into a two-dimensional, nanoscale structure made of DNA.
DNA find
A Queensland University of Technology-led collaboration with University of Adelaide reveals that Australia's pint-sized banded hare-wallaby is the closest living relative of the giant short-faced kangaroos which roamed the continent for millions of years, but died out about 40,000 years ago.
DNA structure impacts rate and accuracy of DNA synthesis
DNA sequences with the potential to form unusual conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.
Changes in mitochondrial DNA control how nuclear DNA mutations are expressed in cardiomyopathy
Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation.
Switching DNA and RNA on and off
DNA and RNA are naturally polarised molecules. Scientists believe that these molecules have an in-built polarity that can be reoriented or reversed fully or in part under an electric field.
New DNA synthesis technique promises rapid, high-fidelity DNA printing
Today, DNA is synthesized as an organic chemist would, using toxic chemicals and error-prone steps that limit accuracy and thus length to about 200 base pairs.
The changing shape of DNA
The shape of DNA can be changed with a range of triggers including copper and oxygen - according to new research from the University of East Anglia.
More Dna News and Dna Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Rethinking Anger
Anger is universal and complex: it can be quiet, festering, justified, vengeful, and destructive. This hour, TED speakers explore the many sides of anger, why we need it, and who's allowed to feel it. Guests include psychologists Ryan Martin and Russell Kolts, writer Soraya Chemaly, former talk radio host Lisa Fritsch, and business professor Dan Moshavi.
Now Playing: Science for the People

#538 Nobels and Astrophysics
This week we start with this year's physics Nobel Prize awarded to Jim Peebles, Michel Mayor, and Didier Queloz and finish with a discussion of the Nobel Prizes as a way to award and highlight important science. Are they still relevant? When science breakthroughs are built on the backs of hundreds -- and sometimes thousands -- of people's hard work, how do you pick just three to highlight? Join host Rachelle Saunders and astrophysicist, author, and science communicator Ethan Siegel for their chat about astrophysics and Nobel Prizes.