Nav: Home

Rotavirus vaccination in infants and young children

May 22, 2017

COLOGNE. Rotaviruses (RV) are the commonest cause of diarrhea in infants and young children worldwide. To protect against rotavirus infection, in 2013 the Standing Committee on Vaccination (STIKO, Ständige Impfkommission) in Germany recommended rotavirus vaccination for all infants. According to current studies, the efficacy of the vaccines in use may be regarded as very high.

Vaccinating babies and young children against rotaviruses is associated with a slight rise in the risk of intussusception. The risk exists for a period of up to a week after the first dose of vaccine has been given. "Intussusception" is the name given to the condition where one part of the intestine folds into another part. A child with an intussusception requires immediate diagnosis and treatment, which is usually conservative. However, the intussusception risk is much lower if the vaccination, which is carried out in a series of two or three doses, is started when the child is aged between 6 and 12 weeks, as recommended by STIKO. This is the conclusion reached by Judith Koch and her co-authors on the basis of a systematic literature review and meta-analysis in the current issue of Deutsches Ärzteblatt International (Dtsch Arztbl Int 2017; 114: 255-62).

Every year, around the world an estimated 453 000 children die before the age of 5 from the effects of a rotavirus infection. Before the introduction of vaccination, rotavirus-related gastroenteritis was the commonest notifiable disease of children in this age group in Germany. About half of these children needed hospital treatment.

In their review article in Deutsches Ärzteblatt International, the authors point out that if vaccination is carried out at the right time, the increase in intussusception risk is only marginal. Their analysis shows that without rotavirus vaccination, one child in 5208 will suffer intussusception during the first 3 months of life, whereas with vaccination the figure is one child in 4785. Parents should be informed of this slightly increased risk during their appointment with the doctor. However, currently as many as 11.2% of infants receive their first dose of vaccine when they are past the age of 3 months, which is associated with a somewhat greater risk of intussusception.

Deutsches Aerzteblatt International

Related Vaccination Articles:

Researchers develop microneedle patch for flu vaccination
A National Institutes of Health-funded study led by a team at the Georgia Institute of Technology and Emory University has shown that an influenza vaccine can produce robust immune responses and be administered safely with an experimental patch of dissolving microneedles.
Rotavirus vaccination in infants and young children
Rotaviruses (RV) are the commonest cause of diarrhea in infants and young children worldwide.
Industry and occupation affect flu vaccination coverage
Not surprisingly, healthcare workers are almost twice as likely to get flu vaccines as those in other occupations.
Child's vaccination data handily available via Kasvuseula service
Parents can now follow their tots' vaccinations via the Kasvuseula online service, which provides analytical data on the child's growth.
Foot-and-mouth crises to be averted with vaccination strategy
Future outbreaks of foot-and-mouth disease (FMD) can be controlled effectively and quickly with vaccinations -- saving millions of pounds and hundreds of thousands of livestock -- according to research by the University of Warwick.
HPV prevalence rates among US men, vaccination coverage
Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, as well as a cause of various cancers, and a new study published online by JAMA Oncology estimates the overall prevalence of genital HPV infection in men ages 18 to 59.
Anesthetic cream best for relieving vaccination pain in infants
For babies under age one year, lidocaine cream, combined with a small amount of sugar given by mouth and infant soothing, can help relieve pain from routine vaccinations, according to a study in Canadian Medical Association Journal.
Measles prevention -- how to pull the trigger for vaccination campaigns?
Routine vaccination has greatly reduced measles deaths in recent years, but very high vaccination coverage is needed to prevent disease outbreaks.
Using satellite images to better target vaccination
Vaccination campaigns can improve prevention and control of disease of outbreaks in the developing world by using satellite images to capture short-term changes in population size.
Maternal vaccination again influenza associated with protection for infants
How long does the protection from a mother's immunization against influenza during pregnancy last for infants after they are born?

Related Vaccination Reading:

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Digital Manipulation
Technology has reshaped our lives in amazing ways. But at what cost? This hour, TED speakers reveal how what we see, read, believe — even how we vote — can be manipulated by the technology we use. Guests include journalist Carole Cadwalladr, consumer advocate Finn Myrstad, writer and marketing professor Scott Galloway, behavioral designer Nir Eyal, and computer graphics researcher Doug Roble.
Now Playing: Science for the People

#530 Why Aren't We Dead Yet?
We only notice our immune systems when they aren't working properly, or when they're under attack. How does our immune system understand what bits of us are us, and what bits are invading germs and viruses? How different are human immune systems from the immune systems of other creatures? And is the immune system so often the target of sketchy medical advice? Those questions and more, this week in our conversation with author Idan Ben-Barak about his book "Why Aren't We Dead Yet?: The Survivor’s Guide to the Immune System".