Nav: Home

Intensive blood pressure can reduce risk of harm to heart muscle

May 22, 2017

WINSTON-SALEM, N.C. - May 22, 2017 - A new study by researchers at Wake Forest Baptist Medical Center has shown that aggressive lowering of blood pressure in people with hypertension reduced the risk of left ventricular hypertrophy (LVH). This condition, the enlargement and thickening of the walls of the heart's main pumping chamber, is the most common complication of high blood pressure and greatly increases the risk of developing cardiovascular disease.

The study is published in the early online edition of the journal Circulation.

"We know that high blood pressure could lead to LVH and we know that lowering this pressure to the recommended levels improves it, but we didn't know if intensive lowering of blood pressure beyond recommended would lead to more improvement in heart muscle," said Elsayed z. Soliman, M.D., lead author of the study and director of the epidemiological cardiology research center at Wake Forest School of Medicine, a part of Wake Forest Baptist.

The objective of the study was to determine if lowering blood pressure below what is generally recommended would lead to more benefits to the heart muscle in terms of thickening (hypertrophy). And if so, would it also prevent other cardiovascular events.

The research team examined these questions through analysis of 8,164 participants from the National Institutes of Health's Systolic Blood Pressure Intervention (SPRINT) trial, which included patients with hypertension but not diabetes. Participants were randomized to the intensive blood pressure lowering group or the standard treatment group.

Study findings showed that lowering systolic blood pressure to less than120 mmHg compared to the standard recommendation of 140 mmHg prevented development of new LVH in those without it and caused regression of LVH in those who already had it.

"We thought that reducing heart muscle thickening would correlate with fewer heart incidents associated with intensive lowering of high blood pressure, but surprisingly that was not the case," Soliman said.

"However, this favorable impact on heart muscle did not explain most of the reduction in cardiovascular events associated with intensive blood pressure lowering. More research is needed to understand what factors determine which patients get the most benefits and less of the harm."

These findings provide further evidence of the benefits of the intensive blood pressure lowering in patients with hypertension, and suggest that these benefits go beyond reducing the pressure and stress on the heart structure.
-end-
Support for the study was provided by the National Institutes of Health (SPRINT) and the Department of Veterans Affairs.

Co-authors include: Walter T. Ambrosius, Ph.D., and Zhu-ming Zhang, M.D., of Wake Forest Baptist; William C. Cushman, M.D., Veterans Affairs Medical Center in Memphis; Jeffrey T. Bates, M.D., Michael E. DeBakey VAMC and Baylor College of Medicine; Javier A. Neyra, M.D., University of Kentucky; Thaddeus Y. Carson, M.D., Augusta University; Leonardo Tamariz, M.D., University of Miami; Lama Ghazi, M.D., University of Minnesota; Monique E. Cho, M.D., University of Utah; Brian P. Shapiro, M.D., Mayo Clinic, Jacksonville, Fla.; Jiang He, M.D., Ph.D., Tulane University School of Public Health and Tropical Medicine; Lawrence J. Fine, M.D., Dr.PH, National Heart, Lung, and Blood Institute; Cora E. Lewis, M.D., University of Alabama at Birmingham.

Wake Forest Baptist Medical Center

Related Blood Pressure Articles:

Do you really have high blood pressure?
A study by researchers at the University of Montreal Hospital Research Centre (CRCHUM) shows that more than half of family doctors in Canada are still using manual devices to measure blood pressure, a dated technology that often leads to misdiagnosis.
Why do we develop high blood pressure?
Abnormally high blood pressure, or hypertension, may be related to changes in brain activity and blood flow early in life.
For some, high blood pressure associated with better survival
Patients with both type 2 diabetes and acute heart failure face a significantly lower risk of death but a higher risk of heart failure-related hospitalizations if they had high systolic blood pressure on discharge from the hospital compared to those with normal blood pressure, according to a study scheduled for presentation at the American College of Cardiology's 66th Annual Scientific Session.
$9.4 million grant helps scientists explore how cell death from high blood pressure fuels even higher pressure
It's been known for decades that a bacterial infection can raise your blood pressure short term, but now scientists are putting together the pieces of how our own dying cells can fuel chronically high, destructive pressure.
Blood pressure diet improves gout blood marker
A diet rich in fruits, vegetables, low-fat dairy and reduced in fats and saturated fats (the DASH diet), designed decades ago to reduce high blood pressure, also appears to significantly lower uric acid, the causative agent of gout.
New tool to improve blood pressure measurement
Oxford University researchers have developed a prediction model that uses three separate blood pressure readings taken in a single consultation and basic patient characteristics to give an adjusted blood pressure reading that is significantly more accurate than existing models for identifying hypertension.
Blood vessels sprout under pressure
It is blood pressure that drives the opening of small capillaries during angiogenesis.
Better blood pressure control -- by mobile phone
An interactive web system with the help of your mobile phone can be an effective tool for better blood pressure control.
Time to reassess blood-pressure goals
High blood pressure or hypertension is a major health problem that affects more than 70 million people in the US, and over one billion worldwide.
With help from pharmacists, better blood pressure costs $22
A pharmacist-physician collaboration in primary-care offices effectively and inexpensively improved patients' high blood pressure.

Related Blood Pressure Reading:

Blood Pressure Down: The 10-Step Plan to Lower Your Blood Pressure in 4 Weeks--Without Prescription Drugs
by Janet Bond Brill PhD RD (Author)

For the nearly 78 million Americans with hypertension, a safe, effective lifestyle plan—incorporating the DASH diet principles and much more—for lowering blood pressure naturally

If you have high blood pressure, you're not alone: nearly a third of adult Americans have been diagnosed with hypertension, and another quarter are well on their way. Yet a whopping 56 percent of diagnosed patients do not have it under control. The good news? Hypertension is easily treatable (and preventable), and you can take action today to bring your blood pressure down in just four... View Details


The High Blood Pressure Hoax
by Sherry A. Rogers (Author)

Blood pressure drugs guarantee you will get worse, for they actually deplete the nutrients that cause high blood pressure, making sure you will need even more medications. They also shrink the brain and raise your risk of heart attack, senility and blindness. High blood pressure is not a deficiency of blood pressure-lowering drugs. But there are dozens of ways you can permanently cure your high blood pressure without drugs. And since healthy blood vessels determine the longevity of every organ in the entire body, you need this book even if you don't have high blood pressure, for vascular... View Details


Lower Your Blood Pressure: A 21-Day DASH Diet Meal Plan to Decrease Blood Pressure Naturally
by Jennifer Koslo PhD RDN CSSD (Author)

Make your healthy heart a habit with the diet and meal plan in Lower Your Blood Pressure.

As 54% of the 75 million Americans who suffer from hypertension know, leading a heart-healthy lifestyle is easier said than done. Recognizing both the rewards and challenges of dieting to lower your blood pressure, Jennifer Koslo, PhD, RD, CSSD, lays out an effective and easy to follow 21-day DASH diet meal plan to help you start and stick to healthy habits. Featuring over 75 low-sodium, high-potassium, and magnesium-filled recipes, Lower Your Blood Pressure is... View Details


Thirty Days to Natural Blood Pressure Control: The No Pressure Solution
by MPH, David DeRose MD (Author), MPH, Greg Steinke MD (Author), Trudie Li FNP (Author), Clifford Goldstein (Editor)

High Blood Pressure. Even if you haven’t received the diagnosis yet, as many as three-quarters of the Western world will have to contend with high blood pressure sometime in their lives. However you no longer need to be a victim. Drs. DeRose and Steinke along with Nurse Practitioner Li draw from cutting-edge medical research and their decades of clinical experience to guide you on an amazing 30-day journey. Learn simple natural strategies that have helped many people decrease or eliminate their dependence on medications. Other titles may promise fast results with natural blood pressure... View Details


The Magnesium Solution for High Blood Pressure (The Square One Health Guides)
by Jay S. Cohen (Author)

Written by health professionals who are well recognized in their respective fields, these concise, easy-to-read books focus on a wide range of important health concerns. From migraine headaches to high cholesterol, each title looks at a specific problem; each provides a clear explanation of the disorder, its causes, and its symptoms; and each offers natural solutions that can either greatly reduce or completely eliminate the problem. Some titles also focus on natural alternatives to drugs with serious side effects―alternatives that in many cases can be used in conjunction with prescription... View Details


Blood Pressure Solution: The Path to Naturally Lower and Control your Blood Pressure, Without Medication
by Margaret Schmitt (Author)

Do you have high blood pressure?
Do you want to find a solution to it?
Do you want to do it without medication and by using all natural remedies?
More than a billion people worldwide have hypertension. It is a leading cause of hundreds of thousands of deaths every year and most drugs only target the symptoms and are not designed to provide a long-term solution.

Now, with Blood Pressure Solution: The Path to Naturally Lower and Control your Blood Pressure, Without Medication, you have the ideal book to help you develop a comprehensive... View Details


Reversing Hypertension: A Vital New Program to Prevent, Treat, and Reduce High Blood Pressure
by Julian Whitaker (Author)

It Strikes One in Four Americans Without Warning... it triples your risk of dying from a heart attack...it increases your risk of stroke sevenfold...it can lead to kidney disease, diabetes, and blindness...and to fight it, you may be taking expensive-and dangerous-drugs. Now Dr. Julian Whitaker, a leading champion of nutritional medicine and the author of Reversing Diabetes and Reversing Heart Disease, unleashes a new weapon in the war against hypertension. His simple yet dramatically effective plan offers: * a comprehensive program of diet, exercise, nutritional supplements, and stress... View Details


Blood Pressure Log Book: Daily Personal Record and your health Monitor Tracking Numbers of Blood Pressure, Heart Rate, Weight, Temperature, Notes With ... Monitoring Health Diary Notebook) (Volume 1)
by Holly Journals (Author)

Daily Personal Record and Monitor Tracking Numbers About Heart Beats Diastolic Pressure, Systolic Pressure, Heart Rate (Pulse), Weight, Temperature, Notes Spiral Bound For 53 Weeks. With Blood Pressure Chart Sheets
Details
Blood pressure log for your daily measurements.
You can use this blood pressure log book send it directly to your doctor.
This blood pressure log is a spiral bound book with table to record - Date / Time / Blood pressure reading Systolic & Diastolic / Heart Rate (Pulse) / weight / Temperature / Notes etc.
Blood Pressure Chart by age.
Pocket... View Details


Blood Pressure: 40 Super-food that will naturally lower your blood pressure
by Arnold Yates (Author)

Use these powerful recipes and strategies to naturally lower your blood pressure! Greetings, My name is Arnold Yates and I am a Doctor and a bodybuilder. I have a PHD in exercise physiology. The reason I created this book is because I don't want people to go through what I went through. Decades of learning, trial and error is compressed into this book. My goal is to spread valuable information to the mass media so that people can improve their health & wellness. Get this book to cut your learning curve and get the body you want in a shorter amount of time. It is important for people with... View Details


Blood Pressure: Blood Pressure Solution: 54 Delicious Heart Healthy Recipes That Will Naturally Lower High Blood Pressure and Reduce Hypertension (Blood Pressure Series) (Volume 2)
by Mark Evans (Author)

Blood Pressure Series Book #2

Are you tired of hearing your doctor talk to you about your rising blood pressure levels? Do you moan inside when health professionals hand you pamphlets regarding information about hypertension? Does it seem like no matter what you eat or do on a regular basis you cannot seem to curb those levels to a reasonable number? If some or all of these apply to you, you have reached out to the right place!

The Blood Pressure Solution was written to bring to light one of the main medical ailments that plague many individuals and why they can be... View Details

Best Science Podcasts 2018

We have hand picked the best science podcasts for 2018. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

The Person You Become
Over the course of our lives, we shed parts of our old selves, embrace new ones, and redefine who we are. This hour, TED speakers explore ideas about the experiences that shape the person we become. Guests include aerobatics pilot and public speaker Janine Shepherd, writers Roxane Gay and Taiye Selasi, activist Jackson Bird, and fashion executive Kaustav Dey.
Now Playing: Science for the People

#478 She Has Her Mother's Laugh
What does heredity really mean? Carl Zimmer would argue it's more than your genes along. In "She Has Her Mother’s Laugh: The Power, Perversions, and Potential of Heredity", Zimmer covers the history of genetics and what kinship and heredity really mean when we're discovering how to alter our own DNA, and, potentially, the DNA of our children.