Nav: Home

Can blood donation programs identify donors with genetic disorder for high cholesterol, coronary artery disease?

May 22, 2019

Bottom Line: This study examined whether a blood donation program could help identify individuals with the often undiagnosed genetic disorder familial hypercholesterolemia, which results in high cholesterol and premature coronary artery disease. Blood donation programs already screen for infectious diseases and may be able to screen for other conditions. This analysis included data from about 1.2 million donors who made a total of 3 million blood donations; total cholesterol levels were determined for these donations. The authors report that of these donors, 3,473 (1 of every 339) met the criteria for familial hypercholesterolemia, similar to estimates in the general population, which suggests blood donation programs may be a method for detecting and notifying donors with this disorder. A limitation of the study was the inability to determine whether there were other causes of hypercholesterolemia.
-end-
Author: Amit Khera, M.D., M.Sc., University of Texas Southwestern Medical Center, Dallas, and coauthors

(doi:10.1001/jamacardio.2019.1518)

Editor's Note: The article contains conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time: https://jamanetwork.com/journals/jamacardiology/fullarticle/2733135?guestAccessKey=55331a28-fe61-453c-9bb7-038ef98848e2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052219

JAMA Cardiology

Related Infectious Diseases Articles:

Certain antidepressants could provide treatment for multiple infectious diseases
Some antidepressants could potentially be used to treat a wide range of diseases caused by bacteria living within cells, according to work by researchers in the Virginia Commonwealth University School of Medicine and collaborators at other institutions.
Opioid epidemic is increasing rates of some infectious diseases
The US faces a public health crisis as the opioid epidemic fuels growing rates of certain infectious diseases, including HIV/AIDS, hepatitis, heart infections, and skin and soft tissue infections.
Infectious diseases could be diagnosed with smartphones in sub-Saharan Africa
A new Imperial-led review has outlined how health workers could use existing phones to predict and curb the spread of infectious diseases.
The Lancet Infectious Diseases: Experts warn of a surge in vector-borne diseases as humanitarian crisis in Venezuela worsens
The ongoing humanitarian crisis in Venezuela is accelerating the re-emergence of vector-borne diseases such as malaria, Chagas disease, dengue, and Zika virus, and threatens to jeopardize public health gains in the country over the past two decades, warn leading public health experts.
Glow-in-the-dark paper as a rapid test for infectious diseases
Researchers from Eindhoven University of Technology (The Netherlands) and Keio University (Japan) present a practicable and reliable way to test for infectious diseases.
More Infectious Diseases News and Infectious Diseases Current Events

Best Science Podcasts 2019

We have hand picked the best science podcasts for 2019. Sit back and enjoy new science podcasts updated daily from your favorite science news services and scientists.
Now Playing: TED Radio Hour

Erasing The Stigma
Many of us either cope with mental illness or know someone who does. But we still have a hard time talking about it. This hour, TED speakers explore ways to push past — and even erase — the stigma. Guests include musician and comedian Jordan Raskopoulos, neuroscientist and psychiatrist Thomas Insel, psychiatrist Dixon Chibanda, anxiety and depression researcher Olivia Remes, and entrepreneur Sangu Delle.
Now Playing: Science for the People

#537 Science Journalism, Hold the Hype
Everyone's seen a piece of science getting over-exaggerated in the media. Most people would be quick to blame journalists and big media for getting in wrong. In many cases, you'd be right. But there's other sources of hype in science journalism. and one of them can be found in the humble, and little-known press release. We're talking with Chris Chambers about doing science about science journalism, and where the hype creeps in. Related links: The association between exaggeration in health related science news and academic press releases: retrospective observational study Claims of causality in health news: a randomised trial This...