Nav: Home

Telemedicine helps improve participation in clinical trials

May 24, 2018

JACKSONVILLE, Fla. (May 24, 2018) - Videos and creative uses of other visuals provide a novel way to obtain informed consent during clinical trials to improve participants' understanding and retention of trial information, according to a study by Nemours Children's Health System presented at the American Thoracic Society (ATS) Annual Conference.

With funding from the National Institutes of Health, Nemours piloted a new clinical trial design to streamline and reduce the time demands and cost of clinical research with the use of technology through a step-by-step video to achieve informed consent, telemedicine appointments, online symptom diaries, and electronic fund transfers for trial compensation.

"Right now, 80 percent of clinical trials are delayed because too few people sign up to participate. Nemours is investigating how we can improve recruitment and participation in research," said Kathryn Blake, PharmD, BCPS, FCCP, director of Nemours' Center for Pharmacogenomics and Translational Research and the lead researcher of the study. "As a part of this project, we looked at new ways to obtain informed consent, by utilizing a 15-minute video that incorporates eLearning principles for a more visually engaging way for participants of all literacy and health literacy levels to digest the information."

In the study, researchers compared participants (children and their parents) who watched a 15-minute video presentation with accompanying tabs that viewers could click for more information, as well as multiple-choice questions to reaffirm what they learned, to participants who read through a traditional 13-page consent document. After completing the informed consent tasks, researchers assessed comprehension of both groups through a 17-item questionnaire. Participants performed similarly on the questionnaire, showing no difference between the two groups. However, five months later when the study was completed, comprehension questionnaires were given again. Caregivers of participants who watched the video presentation retained more information about the study design than those who completed the traditional consent forms.

"The idea of using videos for this process allows families to complete the consent task remotely, which is in line with Nemours' commitment to help families receive exactly the care they need and want, how and when they need and want it," said Blake.
-end-
Nemours is a pioneer in the use of telemedicine to improve pediatric research. In addition to this ongoing study, researchers are also using these tools to screen patients for other clinical trials. For example, Richard Finkel, MD, chief of neurology at Nemours Children's Hospital in Orlando, uses telemedicine to determine eligibility of children with Spinal Muscular Atrophy (SMA) to participate in the health system's research on the disease. This reduces the demands on families, especially those that may need to travel to participate in these studies.

About Nemours Children's Health System

Nemours Children's Health System is an internationally recognized children's health system that owns and operates the Nemours/Alfred I. duPont Hospital for Children in Wilmington, Del., and Nemours Children's Hospital in Orlando, along with major pediatric specialty clinics in Delaware, Florida, Pennsylvania and New Jersey. Established as The Nemours Foundation through the legacy and philanthropy of Alfred I. duPont, Nemours offers pediatric clinical care, research, education, advocacy, and prevention programs to all families in the communities it serves.

Nemours

Related Clinical Trials Articles:

Review evaluates how AI could boost the success of clinical trials
In a review publishing July 17, 2019 in the journal Trends in Pharmacological Sciences, researchers examined how artificial intelligence (AI) could affect drug development in the coming decade.
Kidney patients are neglected in clinical trials
The exclusion of patients with kidney diseases from clinical trials remains an unsolved problem that hinders optimal care of these patients.
Clinical trials beginning for possible preeclampsia treatment
For over 20 years, a team of researchers at Lund University has worked on developing a drug against preeclampsia -- a serious disorder which annually affects around 9 million pregnant women worldwide and is one of the main causes of death in both mothers and unborn babies.
Underenrollment in clinical trials: Patients not the problem
The authors of the study published this month in the Journal of Clinical Oncology investigated why many cancer clinical trials fail to enroll enough patients.
When designing clinical trials for huntington's disease, first ask the experts
Progress in understanding the genetic mutation responsible for Huntington's disease (HD) and at least some molecular underpinnings of the disease has resulted in a new era of clinical testing of potential treatments.
New ALS therapy in clinical trials
New research led by Washington University School of Medicine in St.
Telemedicine helps improve participation in clinical trials
Videos and creative uses of other visuals provide a novel way to obtain informed consent during clinical trials to improve participants' understanding and retention of trial information, according to a study by Nemours Children's Health System presented at the American Thoracic Society (ATS) Annual Conference.
Not enough women included in some heart disease clinical trials
Women are underrepresented in clinical trials for heart failure, coronary artery disease and acute coronary syndrome but proportionately or overrepresented in trials for hypertension, atrial fibrillation and pulmonary arterial hypertension, when compared to incidence or prevalence of women within each disease population, according to a study in the Journal of the American College of Cardiology.
BU: Obese patients underrepresented in cancer clinical trials
A new review by Boston University School of Public Health researchers found that less than one-fifth of participants in cancer-related clinical trials are obese.
Are women really under-represented in clinical trials?
Several studies have reported a lack of gender diversity in clinical trials, with trials including mostly adult males; however, a recent review of publicly available registration data of clinical trials at the US Food and Drug Administration for the most frequently prescribed drug classes found no evidence of any systemic significant under-representation of women.
More Clinical Trials News and Clinical Trials Current Events

Top Science Podcasts

We have hand picked the top science podcasts of 2019.
Now Playing: TED Radio Hour

Risk
Why do we revere risk-takers, even when their actions terrify us? Why are some better at taking risks than others? This hour, TED speakers explore the alluring, dangerous, and calculated sides of risk. Guests include professional rock climber Alex Honnold, economist Mariana Mazzucato, psychology researcher Kashfia Rahman, structural engineer and bridge designer Ian Firth, and risk intelligence expert Dylan Evans.
Now Playing: Science for the People

#540 Specialize? Or Generalize?
Ever been called a "jack of all trades, master of none"? The world loves to elevate specialists, people who drill deep into a single topic. Those people are great. But there's a place for generalists too, argues David Epstein. Jacks of all trades are often more successful than specialists. And he's got science to back it up. We talk with Epstein about his latest book, "Range: Why Generalists Triumph in a Specialized World".
Now Playing: Radiolab

Dolly Parton's America: Neon Moss
Today on Radiolab, we're bringing you the fourth episode of Jad's special series, Dolly Parton's America. In this episode, Jad goes back up the mountain to visit Dolly's actual Tennessee mountain home, where she tells stories about her first trips out of the holler. Back on the mountaintop, standing under the rain by the Little Pigeon River, the trip triggers memories of Jad's first visit to his father's childhood home, and opens the gateway to dizzying stories of music and migration. Support Radiolab today at Radiolab.org/donate.