Nav: Home

Energy drinks may increase risk of heart function abnormalities and blood pressure changes

May 29, 2019

DALLAS, May 29, 2019 -- Drinking 32 ounces of an energy drink in a short timespan may increase blood pressure and the risk of electrical disturbances in the heart, which affect heart rhythm, according to a small study published in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

The study enrolled 34 healthy volunteers between the ages of 18 and 40 years. Participants were randomly assigned to drink 32 ounces of one of two commercially available caffeinated energy drinks or a placebo drink on three separate days. The drinks were consumed within a 60-minute period but no faster than one 16-ounce bottle in 30 minutes.

Researchers measured the electrical activity of the volunteers' hearts by electrocardiogram, which records the way a heart is beating. They also recorded participant's blood pressure. All measurements were taken at the study's start and every 30 minutes for 4 hours after drink consumption.

Both energy beverages tested contained 304 to 320 milligrams of caffeine per 32 fluid ounces. Caffeine at doses under 400 milligrams is not expected to induce any electrocardiographic changes. Other common ingredients in the energy drinks in the study included taurine (an amino acid), glucuronolactone (found in plants and connective tissues) and B-vitamins. The placebo drink contained carbonated water, lime juice and cherry flavoring.

In participants who consumed either type of energy drink, researchers found that the QT interval was 6 milliseconds or 7.7 milliseconds higher at 4 hours compared to placebo drinkers. The QT interval is a measurement of the time it takes ventricles in the heart (the lower chambers) to prepare to generate a beat again. If this time interval is either too short or too long, it can cause the heart to beat abnormally. The resulting arrhythmia can be life-threatening.

The results of the study confirm previous findings and suggest that the QT interval changes are generally sustained over the four-hour monitoring period rather than being a short-lasting effect after consuming 32-ounces of an energy drink.

Researchers also found a statistically significant 4 to 5 mm Hg increase in systolic and diastolic blood pressure in participants who consumed the energy drinks.

"We found an association between consuming energy drinks and changes in QT intervals and blood pressure that cannot be attributed to caffeine. We urgently need to investigate the particular ingredient or combination of ingredients in different types of energy drinks that might explain the findings seen in our clinical trial," said lead author Sachin A. Shah, Pharm.D., professor of pharmacy practice at University of the Pacific, Thomas J. Long School of Pharmacy and Health Sciences in Stockton, California.

The study is the largest controlled study of the effects of energy drinks on the heart and blood pressure in young healthy volunteers. Estimates indicate that about 30% of teenagers between the ages of 12 through 17 years in the United States consume energy drinks on a regular basis, which have been linked to increased emergency room visits and death.

"Energy drinks are readily accessible and commonly consumed by a large number of teens and young adults, including college students. Understanding how these drinks affect the heart is extremely important," said study co-author Kate O'Dell, Pharm.D., professor of pharmacy and director of experiential programs at the Thomas J. Long School of Pharmacy and Health Sciences.

Among the study's limitations, it was designed to assess the effects of short-term consumption of an energy drink and does not provide insight into long-term effects nor the effects of routine energy drink consumption. Additionally, energy drink consumption was evaluated alone, and it is not uncommon for energy drinks to be consumed in combination with other substances such as alcohol. Finally, the study included only healthy individuals between the ages of 18 to 40 years and the results may be different in other populations.

"The public should be aware of the impact of energy drinks on their body especially if they have other underlying health conditions," Shah said. "Healthcare professionals should advise certain patient populations, for example, people with underlying congenital or acquired long QT syndrome or high blood pressure, to limit or monitor their consumption."
-end-
Other co-authors are Andy H. Szeto, Pharm.D.; Raechel Farewell, Pharm.D.; Allen Shek, Pharm.D.; Dorothy Fan, Pharm.D.; Kathy N. Quach, Pharm.D.; Mouchumi Bhattacharyya, Ph.D.; Jasmine Elmiari, B.A., Winny Chan; Nancy Nguyen, Pharm.D.; Tracey J. McGaughey, Pharm.D.; Javed M. Nasir, M.D.; and Sanjay Kaul, M.D. Author disclosures are on the manuscript.

The University of the Pacific supported the study.

Additional Resources:
  • After May 29, 2019 view the manuscript online.
  • Caffeine and Heart Disease.
  • Energy drinks linked to more heart, blood pressure changes than caffeinated drinks alone.
  • Follow AHA/ASA news on Twitter @HeartNews


American Heart Association

Related Blood Pressure Articles:

Children who take steroids at increased risk for diabetes, high blood pressure, blood clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.
High blood pressure treatment linked to less risk for drop in blood pressure upon standing
Treatment to lower blood pressure did not increase and may decrease the risk of extreme drops in blood pressure upon standing from a sitting position.
Changes in blood pressure control over 2 decades among US adults with high blood pressure
National survey data were used to examine how blood pressure control changed overall among U.S. adults with high blood pressure between 1999-2000 and 2017-2018 and by age, race, insurance type and access to health care.
Transient increase in blood pressure promotes some blood vessel growth
Blood vessels are the body's transportation system, carrying oxygen and nutrients to cells and whisking away waste.
Effect of reducing blood pressure medications on blood pressure control in older adults
Whether the amount of blood pressure medications taken by older adults could be reduced safely and without a significant change in short-term blood pressure control was the objective of this randomized clinical trial that included 534 adults 80 and older.
Brain blood flow sensor discovery could aid treatments for high blood pressure & dementia
A study led by researchers at UCL has discovered the mechanism that allows the brain to monitor its own blood supply, a finding in rats which may help to find new treatments for human conditions including hypertension (high blood pressure) and dementia.
Here's something that will raise your blood pressure
The apelin receptor (APJ) has been presumed to play an important role in the contraction of blood vessels involved in blood pressure regulation.
New strategy for treating high blood pressure
The key to treating blood pressure might lie in people who are 'resistant' to developing high blood pressure even when they eat high salt diets, shows new research published today in Experimental Physiology.
Arm cuff blood pressure measurements may fall short for predicting heart disease risk in some people with resistant high blood pressure
A measurement of central blood pressure in people with difficult-to-treat high blood pressure could help reduce risk of heart disease better than traditional arm cuff readings for some patients, according to preliminary research presented at the American Heart Association's Hypertension 2019 Scientific Sessions.
Heating pads may lower blood pressure in people with high blood pressure when lying down
In people with supine hypertension due to autonomic failure, a condition that increases blood pressure when lying down, overnight heat therapy significantly decreased systolic blood pressure compared to a placebo.
More Blood Pressure News and Blood Pressure Current Events

Trending Science News

Current Coronavirus (COVID-19) News

Top Science Podcasts

We have hand picked the top science podcasts of 2020.
Now Playing: TED Radio Hour

Listen Again: The Power Of Spaces
How do spaces shape the human experience? In what ways do our rooms, homes, and buildings give us meaning and purpose? This hour, TED speakers explore the power of the spaces we make and inhabit. Guests include architect Michael Murphy, musician David Byrne, artist Es Devlin, and architect Siamak Hariri.
Now Playing: Science for the People

#576 Science Communication in Creative Places
When you think of science communication, you might think of TED talks or museum talks or video talks, or... people giving lectures. It's a lot of people talking. But there's more to sci comm than that. This week host Bethany Brookshire talks to three people who have looked at science communication in places you might not expect it. We'll speak with Mauna Dasari, a graduate student at Notre Dame, about making mammals into a March Madness match. We'll talk with Sarah Garner, director of the Pathologists Assistant Program at Tulane University School of Medicine, who takes pathology instruction out of...
Now Playing: Radiolab

What If?
There's plenty of speculation about what Donald Trump might do in the wake of the election. Would he dispute the results if he loses? Would he simply refuse to leave office, or even try to use the military to maintain control? Last summer, Rosa Brooks got together a team of experts and political operatives from both sides of the aisle to ask a slightly different question. Rather than arguing about whether he'd do those things, they dug into what exactly would happen if he did. Part war game part choose your own adventure, Rosa's Transition Integrity Project doesn't give us any predictions, and it isn't a referendum on Trump. Instead, it's a deeply illuminating stress test on our laws, our institutions, and on the commitment to democracy written into the constitution. This episode was reported by Bethel Habte, with help from Tracie Hunte, and produced by Bethel Habte. Jeremy Bloom provided original music. Support Radiolab by becoming a member today at Radiolab.org/donate.     You can read The Transition Integrity Project's report here.